Results 71 to 80 of about 173,599 (327)

Predictive factors of clinical evolution in hospitalized patients with lupus nephritis [PDF]

, 2022
Lis Faviola Rondelli Martínez, Dora Montiel-Jarolín, Hugo Javier Figueredo Martínez, Luis Enrique Duarte Arévalos, Edis Fabiola Olmedo Mercado, Elvis Javier Ibáñez Franco, Fabiola De Jesús Giménez Vázquez, Alma María Carmelita Fretes Ovelar   +7 more
openalex   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Dr. Hans Kohn and the political takeover of the Berlin Medical Society by the National Socialist regime in 1933

The Anatomical Record, EarlyView.
Abstract To solidify their power over society, totalitarian regimes will usually eliminate any dissent, any perceived threats early on. These threats include not only political enemies but also educated and independent segments of society, such as professional associations.
Michael Hortsch
wiley   +1 more source

Single cell RNA sequencing to dissect the molecular heterogeneity in lupus nephritis.

JCI Insight, 2017
Lupus nephritis is a leading cause of mortality among systemic lupus erythematosus (SLE) patients, and its heterogeneous nature poses a significant challenge to the development of effective diagnostics and treatments.
E. Der, Saritha Ranabothu, H. Suryawanshi, K. Akat, R. Clancy, Pavel Morozov, Manjunath Kustagi, Mareike Czuppa, P. Izmirly, H. M. Belmont, Tao Wang, N. Jordan, Nicole Bornkamp, Janet Nwaukoni, J. Martínez, B. Goilav, J. Buyon, T. Tuschl, C. Putterman   +18 more
semanticscholar   +1 more source

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

Arthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Avaliação de 100 pacientes com nefrite lúpica acompanhados por dois anos Analysis of 100 patients with lupus nephritis followed up for 2 years

Revista Brasileira de Reumatologia, 2009
OBJETIVOS: Determinar a frequência de remissão total e parcial no tratamento da nefrite lúpica aos 12 e 24 meses de seguimento. Comparar esses subgrupos aos 12 meses, correlacionando as variáveis renais iniciais com a resposta ao tratamento.
Ana Karla Guedes de Melo, Alessandra Barbosa Avelar, Flávia Kamy Marciel Maegawa, Branca Dias Batista de Souza   +3 more
doaj   +1 more source

Lupus nephritis: challenges and progress.

Current Opinion in Rheumatology, 2019
PURPOSE OF REVIEW The management of lupus nephritis remains unsatisfactory due to insufficiently effective treatment regimens and the dearth of reliable predictors of disease onset or progression to guide individualized therapeutic decisions. This review
A. Davidson, C. Aranow, M. Mackay
semanticscholar   +1 more source

Reactive Oxygen Species–Induced Modifications of Fibrin Clots as a Link Between Immune Responses and Atherothrombosis in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Cardiovascular events are major determinants of morbidity and mortality in systemic lupus erythematosus (SLE), particularly in patients with renal involvement. Although oxidative stress has been implicated in driving vascular and renal damage in SLE, the specific mechanisms remain unclear.
Matteo Becatti, Giacomo Emmi, Alessandra Bettiol, Amanda Mannucci, Flavia Rita Argento, Eleonora Fini, Serena Borghi, Francesca Nencini, Maria Nicastro, Irene Mattioli, Elena Silvestri, Augusto Vaglio, Domenico Prisco, Claudia Fiorillo   +13 more
wiley   +1 more source

Nephroprotective Effect of Aged Black Garlic Extract as a Functional Flock Medicinal on Sodium Benzoate-Induced Chronic Kidney Disease in Albino Rats

Life
Sodium benzoate, a common food preservative, has been linked to oxidative stress, inflammation, and potential damage to various organs, including the kidneys.
Marwa A. Sheir, Ameerah M. Almaski, Manal A. Almughamisi, Suha H. Abduljawad, Essam M. Elsebaie, Rania A. Ahmed   +5 more
doaj   +1 more source

Obesity is associated with Henoch-Schönlein Purpura Nephritis and development of end-stage renal disease in children

Renal Failure, 2019
Objectives: To explore the association of obesity with the occurrence of Henoch-Schönlein Purpura Nephritis (HSPN) and development of end-stage renal disease (ESRD) in children with Henoch-Schönlein Purpura (HSP).
Xin Zheng, Qiaobin Chen, Lang Chen
doaj   +1 more source