Results 51 to 60 of about 14,084 (155)

Mortality Patterns and Phenotypic Clusters in Trisomy 13: A Population‐Based Study From Japan

American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 329-338, February 2026.
ABSTRACT Trisomy 13, the third most common autosomal trisomy after trisomy 21 and trisomy 18, is associated with a significantly high infant mortality rate. However, large‐scale studies examining causes of death in trisomy 13 remain scarce. Therefore, we aimed to better understand the mortality patterns.
Narumi Kato, Naho Morisaki, Akinori Moriichi   +2 more
wiley   +1 more source

Significant haematuria caused by a pseudo-aneurysm in nephroblastoma

Journal of Pediatric Surgery Case Reports, 2019
A 7-year-old boy presented with a nephroblastoma, frank haematuria and hypovolemic shock. The haemorrhage was controlled with embolization of the right renal artery and followed by a nephrectomy.
Jaques van Heerden, Hansraj Mangray, Fernando Ghimenton, Deneys Reitz   +3 more
doaj   +1 more source

EGR1 Nuclear Condensates Promote Renal Cyst Development in Polycystic Kidney Disease

Exploration, Volume 6, Issue 1, February 2026.
ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is marked by aberrant cell proliferation driven by cAMP‐PKA and MAPK signaling pathways. EGR1, a transcription factor directly activated by the above two pathways, is critical in the over‐proliferation of tumor cells, which share similarities with cystic epithelial cells in ADPKD. This study
Chaoqun Ren, Zhaoxu Wu, Min Li, Yaqin Du, Hong Zhou, Yazhu Quan, Mengyao Xiong, Yiming Wang, Zhiwei Qiu, Shuai Zhu, Xiaowei Li, Jinzhao He, Cai Gao, Hui Cai, Tingting Li, Baoxue Yang   +15 more
wiley   +1 more source

Efficacy of Anti‐Adhesive Barriers on Outcomes Following Pediatric Abdominal Surgery: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims The efficacy of anti‐adhesive barriers in preventing clinically significant adhesional small bowel obstruction (ASBO) in the pediatric population is poorly defined. This review seeks to evaluate the utility of anti‐adhesive barriers in pediatric populations undergoing abdominopelvic surgery.
Khang Duy Ricky Le, Shasha Haycock, Annie Jiao Wang   +2 more
wiley   +1 more source

Genomic Profiling of Pediatric Solid Tumors With a Dual DNA/RNA Panel: JCCG‐TOP2 Study

Cancer Science, Volume 117, Issue 2, Page 522-535, February 2026.
In the JCCG‐TOP2 nationwide pediatric cancer genomic profiling study, 204 patients' tumors and peripheral blood from 50 institutions across Japan were successfully analyzed using a dual DNA/RNA panel. A total of 147 (72%) had potentially actionable findings, including diagnostic, prognostic, and therapeutic findings in 111 (54%), 61 (30%), and 64 (31%),
Kayoko Tao, Takako Yoshioka, Miho Kato, Kazuyuki Komatsu, Shinichi Tsujimoto, Kenichi Sakamoto, Kazuki Tanimura, Minako Sugiyama, Masahiro Sekiguchi, Yoshiko Nakano, Yoshihiro Otani, Yasushi Yatabe, Akihiko Yoshida, Hajime Okita, Junko Hirato, Kenichi Kohashi, Yukichi Tanaka, Shinji Kohsaka, Takashi Kubo, Kuniko Sunami, Makoto Hirata, Shuichi Tsutsumi, Hiroyuki Aburatani, Katsuyoshi Koh, Masahiro Hirayama, Shuhei Karakawa, Yukayo Terashita, Hiroyuki Fujisaki, Takeshi Yagi, Akihiro Yoneda, Shinji Mochizuki, Hiroyuki Shichino, Tatsuya Suzuki, Tetsuya Takimoto, Koichi Ichimura, Chitose Ogawa, Kimikazu Matsumoto, Hitoshi Ichikawa, Motohiro Kato   +38 more
wiley   +1 more source

Safety and Efficacy of Nephron‐Sparing Surgery in Bilateral Wilms Tumors: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Bilateral Wilms tumor (BWT) presents a significant challenge in pediatric oncology, necessitating a delicate balance between achieving oncological control and preserving renal function. While nephron‐sparing surgery (NSS) has emerged as a promising alternative to radical nephrectomy, its overall safety and efficacy profile ...
Menna Sarhan, Yasmine Adel Mohammed, Ayah Abdulgadir, Ibrahim Moqbel, Yehia Nabil Abdalla, Salma Allam, Ahmad Alkheder, Khaled Alsayed Abualkhair   +7 more
wiley   +1 more source

The Standardized Histogram Shift of T2 Magnetic Resonance Image (MRI) Signal Intensities of Nephroblastoma Does Not Predict Histopathological Diagnostic Information

Cancer Informatics, 2015
The objective of this study is to assess standardized histograms of signal intensities of T2-weighted magnetic resonance image (MRI) modality before and after preoperative chemotherapy for nephroblastoma (Wilms’ tumor). All analyzed patients are enrolled
Sabine Müller, Ruslan David, Kostas Marias, Norbert Graf   +3 more
doaj   +1 more source

Endoscopic bile duct stenting as preliminary treatment of complicated choledochal malformation before definitive surgery

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 1, Page 175-183, January 2026.
Left picture: ERCP before stent placement. Right picture: ERCP after placement of two stents. Abstract Objectives Acute pancreatitis or obstruction is considered an indication for urgent surgery in patients with choledochal malformation. However, in this inflammatory stage, surgery can be challenging.
Johannes Weidner, Joachim Friedrich Kuebler, Andrea Schneider, Jens Dingemann, Ulrich Baumann, Eva‐Doreen Pfister, Nagoud Schukfeh   +6 more
wiley   +1 more source

Nephroblastoma in a 51-year-old Male

Philippine Journal of Pathology
Nephroblastoma is an uncommon renal malignancy primarily observed in the pediatric population, with its occurrence in adults being exceedingly infrequent.
Eldimson Bermudo, Jon Paolo Tan, Al-Zamzam Abubakar   +2 more
doaj   +1 more source

Exploring Wilms Tumour: A Series of Four Cases [PDF]

National Journal of Laboratory Medicine
Wilms tumour, or nephroblastoma, is a common neoplasm in children, with a mean age of incidence between 2-5 years and no sex predilection. The incidence accounts for approximately 7.8 cases per million children, with bilaterality occurring in 5-10% of ...
R Aiswarya, K Chandramouleeswari, M Dougul Regis   +2 more
doaj   +1 more source