Results 171 to 180 of about 165,276 (249)

Total Nephron Number: A Novel Predictor of Disease Progression in IgA Nephropathy. [PDF]

Kidney360
Miyasato Y, Yokoi H.
europepmc   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, EarlyView.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source

Immunoglobulin A Nephropathy With Associated Thrombotic Microangiopathy: Biopsy and Clinical Case Series. [PDF]

Clin Med Insights Case Rep
Fekrat R, Demirci AN, Gee C, Kharabaf S, Tadros M, Nguyen M, Le D, Vadpey O, Zuckerman J, Hanna R.   +9 more
europepmc   +1 more source

TREM2 in Macrophages Promotes Renal Fibrosis via Activation of β‐Catenin Signalling Pathway in Obstructive Nephropathy

Cell Proliferation, EarlyView.
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) promotes obstructive nephropathy progression by activating the β‐catenin signalling pathway, driving M2 macrophage polarisation, migration and fibrogenic gene expression. targeted inhibition of TREM2 thus represents a promising novel strategy against renal fibrosis.
Jia Wei, Zixia Li, Gengyu Du, Ting Chen, Min Yang, Zhen Yuan, Yidan Zheng, Xiang Yan   +7 more
wiley   +1 more source

Picture living with diabetes: A photovoice study of young adults' efforts in making diabetes care fit into their lives

Diabetic Medicine, EarlyView.
Abstract Aim This study aimed to identify what young adults with type 1 diabetes (T1D) do to make diabetes care fit in their lives and the impact of diabetes and diabetes care on living. Methods Dutch young adults with T1D (18–30 years old) submitted photographed real‐life situations of efforts to make care fit and of the impact of care on their lives.
Anka Van Gastel, Matthijs Graner‐Baars, Eelco J. P. De Koning, Victor M. Montori, Viet‐Thi Tran, Sean F. Dinneen, Jessica Mesman, Joris Swaak, Henk‐Jan Aanstoot, Anne M. Stiggelbout, Marleen Kunneman   +10 more
wiley   +1 more source

A call to action: A consensus statement on knowledge gaps and research priorities on the management of women with early onset type 2 diabetes in the preconception, pregnancy and postnatal periods

Diabetic Medicine, EarlyView.
Abstract Aims Research to inform, co‐develop and evaluate optimal care for women with early‐onset type 2 diabetes (EOT2D) before, during and after pregnancy is lacking. Informed by patient perspectives and the results of the James Lind Alliance priority‐setting partnership in diabetes in pregnancy, we aimed to develop a consensus statement to guide ...
Sara L. White, Danielle Schoenaker, Sharon Mackin, Rita Forde, Angela C. Flynn, Eleanor Dyer, Nicola Heslehurst, Robert Lindsay, Claire L. Meek   +8 more
wiley   +1 more source

Systemic Lupus Erythematosus With IgA Nephropathy: Challenges in Diagnosis and Management. [PDF]

Am J Case Rep
Shah M, Malik F, Shah M, Patel MD, Pathakjee R, Pandya S.   +5 more
europepmc   +1 more source

High prevalence of maturity‐onset diabetes of the young in the Czech Republic: A 25‐year nationwide registry‐based study

Diabetic Medicine, EarlyView.
Abstract Aims Maturity‐Onset Diabetes of the Young (MODY) results from a single‐gene defect. This study aimed to determine the minimal prevalence, screening indicators, as well as clinical characteristics of MODY in the Czech Republic based on data from 25 years of the nationwide registry.
Petra Dusatkova, Marketa Pavlikova, Michaela Cermakova, Klara Vesela, Katerina Kolarova, Lenka Elblova, Zdenek Sumnik, Jan Lebl, Stepanka Pruhova   +8 more
wiley   +1 more source

Principles for Optimal Drug Selection in IgA Nephropathy-Time for Integrating Pathogenesis and Clinical Markers to Guide Therapy. [PDF]

Nephrology (Carlton)
Suzuki Y.
europepmc   +1 more source

Colorectal cancer outcomes show relationships with the type and extent of vascular complications in individuals with diabetes: A population‐based study

Diabetic Medicine, EarlyView.
Abstract Aims Diabetes is associated with poorer prognosis and treatment‐related outcomes in patients with cancer. Major surgical resection is the mainstay of potentially curative treatment for colorectal cancer (CRC). This study aimed to assess whether the risk of adverse outcomes for individuals with diabetes and CRC varies by diabetes status and ...
Rebecca J. Birch, John C. Taylor, Amy Downing, Philip Quirke, Paul Finan, Katie Spencer, Eva J. A. Morris, Simon Howell, Ramzi A. Ajjan   +8 more
wiley   +1 more source