Results 171 to 180 of about 367,294 (339)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley +1 more source
Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng +6 more
wiley +1 more source
IgA nephropathy: a review of existing and emerging therapies [PDF]
, 2023 Sahibzadi Mahrukh Noor +5 more
openalex +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Diabetic retinopathy (DR) is a leading cause of vision impairment in patients diagnosed with Type 2 diabetes mellitus (T2DM). Awareness of risk factors is necessary to reduce or prevent harmful effects of DR such as irreversible vision loss, and to help ensure early treatment.
Yu‐Chi Sung +8 more
wiley +1 more source
Metabolic Dysfunction‐Associated Steatotic Liver Disease After Hepatitis C Virus Cure
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Hepatitis C virus (HCV) infection is an infectious disease carrying a high risk of metabolic disorders. Chronic HCV (CHC) patients can possess extrahepatic manifestations such as diabetes, steatotic liver disease (SLD), and other metabolic alterations.
Chung‐Feng Huang +3 more
wiley +1 more source
The causal role between circulating immune cells and diabetic nephropathy: a bidirectional Mendelian randomization with mediating insights [PDF]
Ning Shen +10 more
openalex +1 more source
Exenatide prevents diabetic nephropathy in a rat model of type 2 diabetes mellitus (fat-fed and streptozotocin-treated rats) [PDF]
, 2017 Tarek K. Motawi +3 more
openalex +1 more source
Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury
Med Research, EarlyView.ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang +13 more
wiley +1 more source