Results 201 to 210 of about 452,381 (401)

Synergistic inhibition of α‐glucosidase and α‐amylase by phenolic compounds isolated from olive oil by‐products

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The inhibition of carbohydrate‐digesting enzymes, α‐glucosidase and α‐amylase, is a key strategy in managing postprandial hyperglycemia in type 2 diabetes. Natural phenolic compounds isolated from olive mill by‐product (alperujo), such as hydroxytyrosol (HT) and trans‐p‐coumaroyl secologanoside (comselogoside, COM), have shown ...
Fátima Rubio‐Senent   +4 more
wiley   +1 more source

Nephropathy in Diabetes [PDF]

open access: yesExperimental and Clinical Endocrinology & Diabetes, 2021
Martina Guthoff   +4 more
openaire   +3 more sources

Mechanistic Insights Into hsa_circ_0005654‐Induced Ferroptosis in Diabetic Foot Ulcers Through IGF2BP2 Interaction

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the molecular mechanism by which hsa_circ_0005654 aggravates diabetic foot ulcers (DFUs) by promoting ferroptosis. A DFU rat model was established, and lentiviral vectors interfering with circ_0005654 and IGF2BP2 expression were injected into DFU rats by tail vein.
Chun‐Meng Li   +4 more
wiley   +1 more source

Angiogenesis as a Therapeutic Target of (Poly)phenols: Tackling Cancer and Vascular‐Related Complications

open access: yesMolecular Nutrition &Food Research, EarlyView.
(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez   +5 more
wiley   +1 more source

Protein Kinase C β Inhibitor LY333531 Attenuates Intercellular Adhesion Molecule-1 and Monocyte Chemotactic Protein-1 Expression in the Kidney in Diabetic Rats

open access: yesJournal of Pharmacological Sciences, 2006
.: In vitro studies have shown that activation of protein kinase C (PKC) is a key mediator of intercellular adhesion molecule-1 (ICAM-1) and monocyte chemoattractant protein-1 (MCP-1) in a range of cell types and in response to high glucose, however, its
Wu Yonggui   +6 more
doaj  

Evolving nutrition therapy in cystic fibrosis: Adapting to the CFTR modulator era

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Cystic fibrosis transmembrane regulator (CFTR)–directed therapies, such as modulators, have transformed the medical management of people with CF, resulting in better lung function, weight, and body mass index in recent years. With improved nutrition status in people on CFTR modulators, the emphasis on a high‐energy, high‐fat diet (the legacy ...
Kay Vavrina   +5 more
wiley   +1 more source

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