Results 61 to 70 of about 3,743 (224)

The Current and Potential Therapeutic Use of Metformin—The Good Old Drug

Pharmaceuticals, 2021
Metformin, one of the oldest oral antidiabetic agents and still recommended by almost all current guidelines as the first-line treatment for type 2 diabetes mellitus (T2DM), has become the medication with steadily increasing potential therapeutic ...
Józef Drzewoski, Markolf Hanefeld
doaj   +1 more source

Designing the Healthcare System for the Fulfilment of Patient Goals: A Patient‐Centric Exploration in the Home Dialysis Context

The International Journal of Health Planning and Management, Volume 41, Issue 1, Page 171-181, January 2026.
ABSTRACT This study investigates patients' goal‐oriented experiences in the context of home dialysis for chronic kidney disease (CKD). The aim is to understand how the home care context can be designed to support chronic patients in achieving their goals. Drawing on goal‐oriented experience theory, we explore how patients' motivations, desired outcomes,
Frederic Ponsignon, Marie‐Julie Catoir Brisson, Susana Paixão‐Barradas, Corinne Grenier, Corinne Isnard Bagnis   +4 more
wiley   +1 more source

Angiotensin II type 1 receptor antagonists and ACE inhibitors in the regulation of hemodynamics and renin-angiotensin-aldosterone system activity: focus on the organ protection

Кардиоваскулярная терапия и профилактика, 2010
Chronic activation of renin-angiotensin-aldosterone system (RAAS) is characterised by vasoconstriction, increased total peripheral vascular resistance, organ and tissue hypoperfusion, fluid detention, increased circulatory volume, increased myocardial ...
M. L. Maksimov, O. V. Dralova, A. K. Starodubtsev   +2 more
doaj  

Effect of Statin Use on Mortality in Individuals With Cardiovascular–Kidney–Metabolic Syndrome: A Retrospective Propensity Score‐Matched Cohort Study

Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Background The present study is aimed at investigating the effects of statins on all‐cause and cardiovascular mortalities in individuals with cardiovascular–kidney–metabolic syndrome (CKMS). Methods Using data from the National Health and Nutrition Examination Survey (NHANES) 1999–2018, we identified individuals with CKMS and categorized them into ...
Cheng Yuan, Yuguo Ge, Wenqi Ge, Huaxue Wang, Ximing Deng, Jinmeng Chen, Kaixuan Niu, Jinhui Xiong, Yang Xu, Kun Lu, Arquimedes Gasparotto Junior   +10 more
wiley   +1 more source

Diagnóstico y tratamiento de la enfermedad de Fabry [PDF]

, 2017
El texto en español se encuentra disponibe en http://doi.org/10.1016/j.medcli.2016.09.047This work was supported by FIS PI13/00047, PI15/00298, CP14/00133, FEDER funds ISCIII-RETIC REDinREN RD12/0021 and RD16/0009, Sociedad Española de Nefrología ...
Ortiz, Alberto, Sánchez-Niño, María Dolores   +1 more
core   +2 more sources

Cardio-renal interrelation: modern view

Кардиоваскулярная терапия и профилактика, 2010
The paper discusses the definition and classification of cardio-renal syndrome (CRS) — a pathological process in heart or kidneys, characterised by acute or chronic dysfunction of one organ which results in acute or chronic failure of the other organ ...
Zh. D. Kobalava, S. V. Villewalde, M. A. Efremovtseva, V. S. Moiseev   +3 more
doaj  

ANGIOTENSIN II RECEPTOR ANTAGONISTS AND NEPHROPROTECTION: PLACE OF OLMESARTAN

Кардиоваскулярная терапия и профилактика, 2013
The paper presents the results of experimental studies and clinical trials which demonstrate nephroprotective effects of olmesartan.
V. V. Fomin
doaj   +1 more source

Clinical Utility of Urinary Cystatin C in Early Screening and Staging of Diabetic Kidney Disease in Type 2 Diabetes

International Journal of Endocrinology, Volume 2026, Issue 1, 2026.
Objectives Diabetic kidney disease (DKD) is a major complication of Type 2 diabetes mellitus (T2DM). Early detection is critical to prevent renal function decline and improve outcomes, but conventional biomarkers (e.g., urinary albumin‐to‐creatinine ratio [UACR] and estimated glomerular filtration rate [eGFR]) have limited sensitivity for early‐stage ...
Shanshan Ji, Fanghao Shang, Bingbing Chen, Wentao Tang, Hua Fang, Jinbao Huang, Yizhong Hu, Suraiya Saleem   +7 more
wiley   +1 more source

Isoliquiritigenin Prevents the Development of Nephropathy by an HFD in Rats Through the Induction of Antioxidant Production and Inhibition of the MD-2/TLR4/NF-κB Pathway

Biology
This study tested the ISL against renal damage induced by a high-fat diet (HFD) and explored its underlying mechanisms. Adult male rats were assigned to four groups: (1) control on a standard diet (STD), (2) ISL on STD (30 mg/kg), (3) HFD, and (4) HFD ...
Mohammed Abdo Yahya, Ghedeir M. Alshammari, Magdi A. Osman, Laila Naif Al-Harbi, Setah Naif Alotaibi   +4 more
doaj   +1 more source

Chrono‐Synergistic Nutrition: Gut Microbiota–Targeted Diets and Circadian‐Aligned First Meal Timing Confer Robust Protection Against Kidney Stone Formation

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
This study reveals that higher Dietary Index for Gut Microbiota (DI‐GM ≥ 6) significantly reduces kidney stone risk by 22.7%. Early breakfast timing (00:00–09:00) provides additional protection. Combining optimal dietary quality with circadian‐aligned meal timing yields synergistic effects, reducing risk by 32% compared to a poor diet with delayed ...
Tianxiang Fu, Xuanhao Zhou, Zhihong Chen, Zhuoyan Huang, Jingxian Li, Qiuyang Li, Wenqi Wu, Yiming Tang   +7 more
wiley   +1 more source