Results 231 to 240 of about 121,280 (344)

Revised therapeutic window for vancomycin in pediatric patients: evidence from a retrospective therapeutic drug monitoring study. [PDF]

BMC Pharmacol Toxicol
Zhang T, Yi J, Cheng H, Han X, Wang Y, Xie J, Yang Q, Hu S, Dong Y.   +8 more
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Advancing transcriptomics-based mechanistic assessment of nephrotoxicity in vitro using the human RPTEC/TERT1 TXG-MAPr gene co-expression network. [PDF]

Toxicol Sci
van Kessel HW, Kunnen SJ, Callegaro G, van de Water B.   +3 more
europepmc   +1 more source

Risk Factors for Vancomycin Nephrotoxicity

, 2014
Verônica T. Costa e Silva, Lia Marçal, Emmanuel A. Burdmann   +2 more
openalex   +1 more source

FB23‐2 and Cisplatin Synergize to Inhibit Head and Neck Squamous Cell Carcinoma by Targeting the XPF/ERCC1 Complex

Cancer Science, EarlyView.
FB23‐2 potentiates cisplatin's antitumor efficacy in head and neck squamous cell carcinoma by disrupting XPF/ERCC1 complex assembly and nuclear translocation, thereby suppressing DNA damage repair machinery and amplifying platinum‐induced tumor cell death.
Yaoqi Jiang, Hongshi Cai, Yue Zhu, Jianfeng Liang, Hongyu Li, Fan Song, Ziyi Wang, Jinsong Hou   +7 more
wiley   +1 more source

Retraction: Potassium bromate-induced nephrotoxicity and potential curative role of metformin loaded on gold nanoparticles. [PDF]

Sci Prog
europepmc   +1 more source

Advances in Pediatric Therapeutic Drug Monitoring. [PDF]

Pediatrics
Coggins SA, Wade KC, Downes KJ.
europepmc   +1 more source

A UK key opinion leader perspective: Navigating the immunological and logistical transformation brought by stem cell‐derived islets for the treatment of type 1 diabetes

Diabetic Medicine, EarlyView.
Abstract Aims To explore UK key‐opinion leader perspectives on the future role of stem cell‐derived islets (sc‐islets) in islet transplantation for people with type 1 diabetes (T1D). Methods Four UK‐based key‐opinion leaders evaluated current limitations of donor islet transplantation and reviewed emerging evidence, clinical pathways and logistical ...
Thomas Strakosch, Shareen Forbes
wiley   +1 more source

State-of-the-Art Research and New Pharmacological Perspectives on Renal Involvement in Duchenne Muscular Dystrophy: A Narrative Review. [PDF]

Biomedicines
Bellis M, Imbrici P, Lenti R, Liantonio A, De Luca A.   +4 more
europepmc   +1 more source

Efficacy, Safety, and Cost-Effectiveness of N-Acetylcysteine in Preventing Amphotericin B Nephrotoxicity in Egyptian Patients with Hematological Malignancies: A Randomized Controlled Trial

Abdel‐Hameed Ibrahim Mohamed Ebid, Haydi Sayed Mohamed, Yusuf Mohammed, Sara Mohamed Mohamed Abdel Motaleb   +3 more
openalex   +2 more sources