Results 251 to 260 of about 72,055 (308)
Inflammation: The Pathological Axis of Cisplatin-Induced Renal Injury. [PDF]
J Inflamm ResTian P +5 more
europepmc +1 more source
Probiotics-enhanced kynurenic acid mitigates cisplatin-induced nephrotoxicity in mice. [PDF]
iScienceLi K +8 more
europepmc +1 more source
Perspective: Taxonomy of Kidney Diseases and Disorders Related to Nephrotoxic Drug Exposure in Hospitalized Patients. [PDF]
Mayo Clin ProcKane-Gill SL +8 more
europepmc +1 more source
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Transplantation Proceedings, 2004
The polypeptide immunosuppressant cyclosporine is a prodrug that binds an intracellular immunophilin. The complex cyclosporine-cyclophilin binds and inhibits the phosphatase activity of calcineurin interfering with the dephosphorilation of members of the nuclear factor of activated T cells, which is involved in the regulation of genes encoding many ...
J M, Grinyó, J M, Cruzado
+7 more sources
The polypeptide immunosuppressant cyclosporine is a prodrug that binds an intracellular immunophilin. The complex cyclosporine-cyclophilin binds and inhibits the phosphatase activity of calcineurin interfering with the dephosphorilation of members of the nuclear factor of activated T cells, which is involved in the regulation of genes encoding many ...
J M, Grinyó, J M, Cruzado
+7 more sources
NeoReviews, 2021
Acute kidney injury (AKI) is classified based on prerenal, intrinsic, and postrenal causes. In the newborn, AKI can occur after an insult during the prenatal, perinatal, or postnatal period. AKI is usually an underrecognized condition and its true incidence is unknown.
Henrique, Soares +13 more
openaire +2 more sources
Acute kidney injury (AKI) is classified based on prerenal, intrinsic, and postrenal causes. In the newborn, AKI can occur after an insult during the prenatal, perinatal, or postnatal period. AKI is usually an underrecognized condition and its true incidence is unknown.
Henrique, Soares +13 more
openaire +2 more sources
Mechanisms of Cisplatin Nephrotoxicity [PDF]
Toxins, 2010 Cisplatin is a widely used and highly effective cancer chemotherapeutic agent. One of the limiting side effects of cisplatin use is nephrotoxicity. Research over the past 10 years has uncovered many of the cellular mechanisms which underlie cisplatin ...
William Reeves +2 more
exaly +2 more sources
Current Drug Target -Infectious Disorders, 2004
The main constraints to the administration of aminoglycosides (AG) are risks of nephrotoxicity and ototoxicity, which can lead to renal and vestibular failure. AG accumulation in the kidney may be related to the dosing schedule. As a result, administration of larger doses on a less frequent basis may reduce the drug accumulation in the renal cortex ...
Rougier, F. +3 more
openaire +3 more sources
The main constraints to the administration of aminoglycosides (AG) are risks of nephrotoxicity and ototoxicity, which can lead to renal and vestibular failure. AG accumulation in the kidney may be related to the dosing schedule. As a result, administration of larger doses on a less frequent basis may reduce the drug accumulation in the renal cortex ...
Rougier, F. +3 more
openaire +3 more sources
Clinica Chimica Acta, 1995
Nephrotoxicity can be grouped by the xenobiotics place of action, by the clinical presentation or by the generic toxic effect. The latter can be dose related, indirect, idiosyncratic or allergic. Nephrotoxicity of lithium, demeclocycline, aminoglycosides, cyclosporine, mercuric ion, nonsteroidal anti-inflammatory drugs, methoxyflurane, ethylene glycol,
M, Werner +3 more
openaire +2 more sources
Nephrotoxicity can be grouped by the xenobiotics place of action, by the clinical presentation or by the generic toxic effect. The latter can be dose related, indirect, idiosyncratic or allergic. Nephrotoxicity of lithium, demeclocycline, aminoglycosides, cyclosporine, mercuric ion, nonsteroidal anti-inflammatory drugs, methoxyflurane, ethylene glycol,
M, Werner +3 more
openaire +2 more sources