Results 121 to 130 of about 20,710 (242)

Inpatient Cardiac Resynchronization Therapy During Heart Failure Hospitalization: A Distinct High‐Risk Phenotype

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background The role of cardiac resynchronization therapy (CRT) during hospitalization for heart failure (HFH) is uncertain, because hospitalized patients were routinely excluded from landmark CRT trials. Despite this, CRT implantation during HFH is common.
Oliver Rees, James Dargan, Jemima Weir, Robin Ray, Giuseppe Rosano, Fadi Johura   +5 more
wiley   +1 more source

Auswirkungen der Angiotensin-Renin-Neprilysin-Inhibition bezogen auf die zentrale Schlafapnoe bei chronischer Herzinsuffizienz

AUSWIRKUNGEN DER ANGIOTENSIN-RENIN-NEPRILYSIN-INHIBITION BEZOGEN AUF DIE ZENTRALE SCHLAFAPNOE BEI CHRONISCHER HERZINSUFFIZIENZ Auswirkungen der Angiotensin-Renin-Neprilysin-Inhibition bezogen auf die zentrale Schlafapnoe bei chronischer Herzinsuffizienz
Fernandes Branco, Roberto
core  

Consequences of Amyloid‐β Deficiency for the Liver

Advanced Science
The hepatic content of amyloid beta (Aβ) decreases drastically in human and rodent cirrhosis highlighting the importance of understanding the consequences of Aβ deficiency in the liver.
Gayane Hrachia Buniatian, Ute Schwinghammer, Roman Tremmel, Holger Cynis, Thomas S. Weiss, Ralf Weiskirchen, Volker M. Lauschke, Sonia Youhanna, Isbaal Ramos, Maria Valcarcel, Torgom Seferyan, Jens‐Ulrich Rahfeld, Vera Rieckmann, Kathrin Klein, Marine Buadze, Victoria Weber, Valentina Kolak, Rolf Gebhardt, Scott L. Friedman, Ulrike C. Müller, Matthias Schwab, Lusine Danielyan   +21 more
doaj   +1 more source

Bowel Obstruction/Ileus Associated With the Use of Glucagon‐Like Peptide‐1 Receptor Agonists: A Nationwide Database Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9941-9954, November 2026.
ABSTRACT Aims The association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and the development of bowel obstruction/ileus remains unclear, and evidence for specific bowel obstruction/ileus subtypes remains limited. We examined the association between GLP‐1RA use and the incidence of bowel obstruction/ileus subtypes across different ...
Yuichiro Matsuo, Akira Okada, Takashi Sakamoto, Hideo Yasunaga   +3 more
wiley   +1 more source

Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Gyuzel Y. Mitronova, Vladimir N. Belov, Constanze Schmidt, Stephan E. Lehnart   +3 more
wiley   +1 more source

Biomarker profiles in late‐life depression and Alzheimer's disease across and beyond the A/T/N framework: A scoping review

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract Depression and Alzheimer's disease (AD) frequently overlap clinically, and depressive symptoms may signal major depressive disorder, a risk factor for AD, or an early manifestation of neurodegeneration. This scoping review mapped biomarker evidence differentiating depression and AD within and beyond the amyloid/tau/neurodegeneration (A/T/N ...
Yiqi Zhu, Nikitha Damera, Ramkrishna K. Singh, Semere Bekena, Laura Kelble, Katherine McGuire, Yikun Hu, Eden Mersiehazen, Gagan Vijay, Arya Nazif, Ramana Kolady, Liwei Xiang, Xian Liu, Shaney Flores, Kaitlyn Dombrowski, Subrata Pal, Angela Hardi, Kaylin Taylor, Jean‐Francois Trani, Beau M. Ances, Eric J. Lenze, Prashanthi Vemuri, Clifford R. Jack Jr., Ronald C. Petersen, Ganesh M. Babulal   +24 more
wiley   +1 more source

Prognostic Significance and Factors Associated With Worsening LV Dilatation in Heart Failure

Clinical Cardiology, Volume 49, Issue 10, October 2026.
Among patients with a hospitalization or ED visit for HF and at least two echocardiograms at least 6 months apart, failure to decrease LVESD by at least 3.13% or an increase in LVEDD of 1.33% were associated with the composite of all‐cause death, HF hospitalization, and ED visits for HF. Figure created using Canva and Servier Medical Art. ED, emergency
Tauben Averbuch, Robert J. H. Miller, Justin Ezekowitz, Jonathan G. Howlett, Finlay A. McAlister, Erik Youngson, Nowell M. Fine   +6 more
wiley   +1 more source

Trends in Angiotensin Receptor-Neprilysin Inhibitor Prescribing Across Australia

Trends in Angiotensin Receptor-Neprilysin Inhibitor Prescribing Across ...
A Hutchison (13320606), J Amerena (13358346), A Narendren (21398702), Chin Hiew (13063968)   +3 more
core  

Beyond the Heart‐Lung Axis: A Review of the Crosstalk Between the Hemodynamic, Neurohormonal, and Immune Systems in Pulmonary Hypertension

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Pulmonary hypertension is driven by dynamic crosstalk beyond the physical connection between the heart and lung, involving neurohormonal systems, immune pathways, and peripheral organs. This review highlights how multisystem signaling contributes to disease progression and may reveal new diagnostic and therapeutic targets.
Alejandro A. Vega, Juliet M. Alfaro, David S. Pinto, Maryam Emamimeybodi, Soban Umar   +4 more
wiley   +1 more source

Angiotensin Receptor and Neprilysin Inhibitors in CKD

: Combined inhibition of neprilysin and the angiotensin II receptor through Angiotensin Receptor-Neprilysin inhibitors (ARNI) has transformed heart failure management and is garnering increasing attention in nephrology.
Cianciolo, Giuseppe, Massimo Iacoviello, Gaetano La Manna, Tomassetti, Alessandro, Fucili, Alessandro, Alessandro Fucili, Antonio De Pascalis, Alessandro Tomassetti, De Pascalis, Antonio, Edoardo Tringali, Vetrano, Daniele, Giuseppe Cianciolo, La Manna, Gaetano, Iacoviello, Massimo, Stefania Marazia, Tringali, Edoardo, Daniele Vetrano, Marazia, Stefania   +17 more
core   +1 more source