The Journal of Clinical Hypertension, Volume 28, Issue 6, June 2026.ABSTRACT Hypertension is a major modifiable risk factor for chronic kidney disease (CKD), accelerating renal injury by promoting arterial stiffness. Estimated pulse wave velocity (ePWV), an indicator of arterial stiffness, is associated with CKD progression, but its relationship with urinary albumin‐to‐creatinine ratio (UACR) in non‐diabetic ...
Kamila Kamili +8 more
wiley +1 more source
Mechanistic Review of Topical Therapies Targeting Dermal Fibroblasts in Skin Aging and Rejuvenation
Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.ABSTRACT Background Skin aging appears in multiple forms, including wrinkles, sagging, scarring, atrophy, and photoaging. Although each phenotype has distinct biological features, all are rooted in dermal fibroblast dysfunction. This review examines the molecular pathways underlying these conditions and evaluates topical interventions designed to ...
Seyedeh Melika Akaberi +2 more
wiley +1 more source
Neuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.Graphical summary of post‐mortem brain tissue findings that differ between symptomatic and asymptomatic AD. Current evidence suggests reduced accumulation of Aβ and p‐tau oligomers, particularly at synapses, preserved neuronal and synaptic integrity and metabolic activity and a dynamic profile of glial and immune responses in ASYMAD.
Thiago Guilherme Rêgo Barros +6 more
wiley +1 more source
Physiological Reports, Volume 14, Issue 11, June 2026.Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists elicit cardiovascular and renal protection. In humans, GLP‐1 reduces plasma angiotensin II (ANGII) and increases renal perfusion, leading to increased natriuresis. The mechanisms underlying suppression of ANGII remain unclear but may involve ACE2 activation and/or a decrease in angiotensinogen.
Ali Asmar +4 more
wiley +1 more source
The Cellular Response Capacity as Diagnostic Head Start in Neutrophil Endotoxemia Sensing
The FASEB Journal, Volume 40, Issue 10, 31 May 2026.This study introduces the neutrophil cellular response capacity (CRC), a flow‐cytometry‐based approach for detecting prior endotoxin exposure across the inflammatory continuum in human whole blood. By comparing baseline and ex vivo restimulated neutrophil marker expression, the CRC identified low‐dose LPS exposure with greater analytical sensitivity ...
David Alexander Christian Messerer +13 more
wiley +1 more source
Neprilysin and Hypertension: Cause, Consequence, or Marker? [PDF]
J Clin Hypertens (Greenwich)Qaseem M, Ali S.
europepmc +1 more source
Clinical outcomes of heart failure with improved ejection fraction in patients treated with angiotensin receptor-neprilysin inhibitor. [PDF]
Korean J Intern MedKim DE +13 more
europepmc +1 more source
Effect of Post-Ablational Angiotensin Receptor-Neprilysin Inhibitor on Atrial Fibrillation Recurrence: A Systematic Review and Meta-Analysis in Asian Population. [PDF]
Clin CardiolWang Y +5 more
europepmc +1 more source
Incidence of Hypotension and Clinical Characteristics After the Introduction of Angiotensin Receptor-Neprilysin Inhibitors in Patients With Acute Decompensated Heart Failure: Effects on Cardiac Rehabilitation. [PDF]
Circ RepAndo K +4 more
europepmc +1 more source