Results 201 to 210 of about 14,163 (275)

In heart failure, echocardiographic parameters of right ventricular function are powerful tools to predict renal failure

ESC Heart Failure, Volume 12, Issue 3, Page 2310-2320, June 2025.
Abstract Background Chronic kidney disease (CKD) has a high prevalence in patients with heart failure (HF) and is associated with prolonged hospitalization, increased need for intensive care and mortality. There is an urgent need to identify factors that influence the interaction between heart and kidney disorders, often described as cardiorenal ...
Alexander Reinecke, Paulina Dißmann, Norbert Frey, Oliver J. Müller, Hatim Seoudy, Johanne Frank, Derk Frank, Martina E. Spehlmann   +7 more
wiley   +1 more source

Mitral valve transcatheter edge‐to‐edge repair in the elderly—A safe and effective therapy

ESC Heart Failure, Volume 12, Issue 3, Page 1663-1675, June 2025.
Mitral valve transcatheter edge‐to‐edge repair in elderly patients is safe and offers comparable mitral valve regurgitation reduction and symptom relief to younger patients. At 3 years, increased all‐cause mortality is observed in elderly patients with advanced heart failure and elevated EuroSCORE II.
Dominik Felbel, Michael Paukovitsch, Matthias Gröger, Sinisa Markovic, Leonhard Schneider, Wolfgang Rottbauer, Mirjam Keßler   +6 more
wiley   +1 more source

Long‐term outcomes of apixaban as main anticoagulant in patients with HeartMate 3 left ventricular assist devices

ESC Heart Failure, Volume 12, Issue 3, Page 1714-1718, June 2025.
Abstract Aims HeartMate 3 (HM3) left ventricular assist devices (LVADs) offer improved haemocompatibility‐related outcomes for end‐stage heart failure patients, facilitating the exploration of alternative anticoagulation therapies beyond warfarin.
Jennifer Jdaidani, Mahmoud Shadi, Nnedi Asogwa, Jennifer Winik, Dora Rossi, Christina Saikus, Maria D. Avila, Geurys R. Rojas‐Marte   +7 more
wiley   +1 more source

Baseline kidney function and the effects of dapagliflozin on health status in heart failure in DEFINE‐HF and PRESERVED‐HF

ESC Heart Failure, Volume 12, Issue 3, Page 1676-1681, June 2025.
Abstract Aims Sodium–glucose co‐transporter‐2 (SGLT2) inhibitors improve health status and outcomes in the setting of heart failure (HF) across the range of ejection fraction (EF). Baseline kidney disease is common in HF, complicates HF management and is strongly linked to worse health status. This study aimed to assess whether the treatment effects of
Andrew P. Ambrosy, Andrew J. Sauer, Shachi Patel, Sheryl L. Windsor, Barry A. Borlaug, Mansoor Husain, Silvio E. Inzucchi, Dalane W. Kitzman, Darren K. McGuire, Sanjiv J. Shah, Kavita Sharma, Guillermo Umpierrez, Mikhail N. Kosiborod   +12 more
wiley   +1 more source

Real‐world outcomes in cardiac resynchronization therapy patients: Primary results of the SMART registry

ESC Heart Failure, Volume 12, Issue 3, Page 1832-1847, June 2025.
Abstract Aims Cardiac resynchronization therapy (CRT) is guideline recommended for the treatment of symptomatic heart failure (HF) with reduced left ventricular ejection fraction and prolonged QRS. However, patients with common comorbidities, such as persistent/permanent atrial fibrillation (AF), are often under‐represented in clinical trials.
Ignacio García‐Bolao, Roy S. Gardner, Daniel Gras, Antonio D'Onofrio, George Mark, Devi Nair, Nicolas Lellouche, Miroslav Novak, Ronald Lo, Engwooi Chew, David Wright, Andrew Kaplan, Matteo Bertini, Sara Veraghtert, Michelle M. Harbin, Elizabeth Matznick, Patrick Yong, Kenneth M. Stein   +17 more
wiley   +1 more source

The ADESTE trial: A phase 2 study of enibarcimab, a monoclonal antibody targeting adrenomedullin, in acute heart failure

ESC Heart Failure, Volume 12, Issue 3, Page 1848-1860, June 2025.
Abstract Aims This study aimed to conduct a phase 2 proof‐of‐concept and safety study to evaluate the effect of ENIBARCIMAB (EN), a non‐neutralizing humanized monoclonal antibody targeting the N‐terminus of adrenomedullin (ADM), administered immediately after stabilization with standard of care (SoC) treatment, in patients hospitalized for acute heart ...
Anggoro Budi Hartopo, Arinal Chairul Achyar, Hendry Purnasidha Bagaswoto, Firandi Saputra, Hasanah Mumpuni, Dyah Adhi Kusumastuti, Teguh Triyono, Usi Sukorini, Metalia Puspitasari, Budi Yuli Setianto, Mohammad Saifur Rohman, Muhammad Anshory, Yoga Waranugraha, Putri Annisa Kamila, Agustin Iskandar, Hani Susianti, Andreas Bergman, Claudia Knothe, Paola Antonini, Salvatore Di Somma   +19 more
wiley   +1 more source

Guideline‐directed medical therapy rates in heart failure patients with reduced ejection fraction in a diverse cohort

ESC Heart Failure, Volume 12, Issue 3, Page 1861-1871, June 2025.
Abstract Aims Guideline‐directed medical therapy (GDMT) is recommended for all patients with heart failure with reduced ejection fraction (HFrEF). Despite this, little data exist describing GDMT use in diverse, real‐world populations including the use of vasodilators, prescribed primarily to Black populations.
Natalia C. Berry, Yi‐Shin Sheu, Karen Chesbrough, R. Clayton Bishop, Suma Vupputuri   +4 more
wiley   +1 more source

Sacubitril/Valsartan: Neprilysin Inhibition 5 Years After PARADIGM-HF.

JACC. Heart failure, 2020
K. Docherty, M. Vaduganathan, S. Solomon, J. McMurray   +3 more
semanticscholar   +1 more source

Predicting right ventricular failure after left ventricular assist device implant: A novel approach

ESC Heart Failure, Volume 12, Issue 3, Page 1916-1931, June 2025.
Abstract Aims Right ventricular (RV) failure (RVF) after left ventricular assist device (LVAD) implant is an important cause of morbidity and mortality. Modern, data‐driven approaches for defining and predicting RVF have been under‐utilized. Methods Two hundred thirty‐two patients were identified with a mean age of 55 years; 40 (17%) were women, 132 ...
Carissa E. Livingston, Dale Kim, Lacey Serletti, Andrea Jin, Sriram Rao, Michael V. Genuardi, Eliot G. Peyster   +6 more
wiley   +1 more source

Poor communication impairs optimal care of patients with heart failure and erectile dysfunction

ESC Heart Failure, Volume 12, Issue 3, Page 1932-1941, June 2025.
Abstract Aims Heart failure (HF) and erectile dysfunction (ED) share numerous risk factors and pathogenetic mechanisms, resulting in a high prevalence of ED among male patients with HF. This questionnaire‐based study aimed to better understand the patient's journey from a patient perspective and that of healthcare professionals (HCPs) regarding ...
Lea Leist, Lenka Hausmann, Carla Pohlink
wiley   +1 more source