Results 101 to 110 of about 446,801 (290)

Case Report: Partial neurectomy and limb-sparing treatment for SOX-10 expressing epithelioid malignant nerve sheath tumour of the tibial nerve

Frontiers in Veterinary Science
IntroductionEpithelioid-variant malignant peripheral nerve sheath tumours (EMPNST) are rare in veterinary medicine and typically have poor outcomes. Limb-sparing partial neurectomy is used for distal peripheral nerve sheath tumours but has not previously
Alexander Spencer-Taylor, Dylan Yaffy, Juan Marti, Maria Miguel-Garcés, Francesca Raimondi   +4 more
doaj   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

Advanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan, Haoming Shu, Rui Gao, Yilong Ren, Wu Ye, Xuhui Ge, Yao Gu, Yufeng Zhu, Xiaokun Wang, Honglin Teng, Xuhui Zhou, Wei Liu, Yang Gao, Jianquan Zhao, Weihua Cai   +14 more
wiley   +1 more source

Synthesis of Ladder and Flexible Polysulfonimides Directly From Anionic Monomers: Investigating Structure–Property Convergence in Succinonitrile–Polymer Electrolyte Blends

Angewandte Chemie, EarlyView.
Direct synthesis of sulfonimide‐based polymers of intrinsic microporosity enables comparison with compositionally similar flexible analogs. Incorporation of a common pore‐filling transport medium drives these fundamentally different polymer architectures toward similar bulk conductivity and mechanical properties while revealing distinct microscopic ion‐
Abraham Herzog‐Arbeitman, Pablo Leon, Benedikt S. Schreib, KyuJung Jun, Jurgis Ruza, Vanesa Munoz Perales, Yang Shao‐Horn, Rafael Gomez‐Bombarelli, Jeremiah A. Johnson   +8 more
wiley   +2 more sources

Comparative Evaluation of Chelator‐Conjugated Peptides for Lead‐Labeled SSTR2‐Targeted Theranostics: Integrated Computational Modeling and Preclinical Validation

Advanced Science, EarlyView.
The study integrates density functional theory with radiochemical and biological validation to compare DOTA‐, PSC‐, and DOTAM‐based chelator‐conjugates for 203Pb/212Pb theranostic applications. Distinct differences in metal coordination, electrostatic properties, conformational flexibility, cellular uptake, biodistribution, and dosimetry are identified
Jeongyun Kim, Na Yeon Han, Ayman Muzammal, Jae Hun Ahn, Changkeun Im, Sujin Kim, Sairan Eom, Choong Mo Kang, Ku Kang, Yong Jin Lee, Kyo Chul Lee, Michael K. Schultz, Dongyoul Lee   +12 more
wiley   +1 more source

Combinatorial Survey of Structural Phase Distribution and Magnetism in Fe‐Ge‐Te Composition‐Spread Thin Film Libraries

Advanced Electronic Materials, EarlyView.
ABSTRACT Magnetic 2‐dimensional (2D) van der Waals (vdW) materials have garnered tremendous attention. The vdW ferromagnet Fe5Ge1Te2 has a Curie temperature Tc of ≈ 270 K, which is tailorable by tuning the stoichiometry and the Fe deficiency to reach room temperature.
Chih‐Yu Lee, Takahiro Yamazaki, Peng Yan, Ryan Kim, Masato Kotsugi, Efrain E. Rodriguez, Joseph W. Bennett, Ichiro Takeuchi   +7 more
wiley   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Nerve-sparing Technique in Rectal Cancer

, 2013
Attention to nerve identification in rectal cancer surgery began in Japan in the 1970s, but it was an American surgeon [1, 2] between the 1970s and 1980s who proposed a combination of the nerve-sparing principle with the TME technique. The result was the
Nicolò de Manzini, PALMISANO, SILVIA, Simonetta Masaro, Piera Leon, MASARO, SIMONETTA, de Manzini, Nicolo', Silvia Palmisano, LEON, PIERA   +7 more
core   +1 more source

Multiple approaches on a high fidelity surgical model for robot-assisted nerve-sparing radical prostatectomy training

Urology Video Journal
Introduction: Robot-assisted radical prostatectomy (RARP) with nerve-sparing is technically demanding and requires mastery of different surgical approaches to preserve functional outcomes while maintaining oncological control. This video demonstrates the
Ringa Maximiliano, Diaz Zorita Victoria, Villamil Wenceslao, Juan Manuel Alvarez, Vitagliano Gonzalo   +4 more
doaj   +1 more source

Nerve-sparing versus non-nerve-sparing radical hysterectomy

There are controversies regarding the long-term oncological safety of preservation of pelvic innervation during radical hysterectomy (RH). This study aimed to analyze the feasibility and safety of nerve-sparing radical hysterectomy (NSRH) for cervical cancer compared with non-NSRH following 17 years of experience in a tertiary cancer referral center ...
Gil-Moreno, Antonio||, Carbonell-Socias, Melchor||, Salicrú, Sabina, Bradbury, Melissa||, García, Ángel, Vergés, Ramona, Puig, Oriol Puig, Sánchez-Iglesias, José Luís, Cabrera Díaz, Silvia||, de la Torre, Javier||, Gómez-Hidalgo, Natalia R., Pérez-Benavente, Assumpció||, Díaz-Feijoo, Berta||   +12 more
openaire   +1 more source

Internet use and adolescent development: A conceptual model integrating behavioral and contextual theories

American Journal of Community Psychology, EarlyView.
Abstract In the digital era, adolescent development is deeply embedded in the cyber environment. Despite ongoing debate on the benefits and/or risks that Internet use brings to adolescents in empirical studies, conceptual and theoretical discussion on the influences of the intensity and modalities of Internet use is peripheral.
Linxiao Zhang, Lin Fang, Faye Mishna, Liangqi Shen   +3 more
wiley   +1 more source