Results 61 to 70 of about 446,801 (290)

Nerve sparing open radical retropubic prostatectomy--does it have an impact on urinary continence?

, 2006
PURPOSE: We prospectively assessed the role of nerve sparing surgery on urinary continence after open radical retropubic prostatectomy. MATERIALS AND METHODS: We evaluated a consecutive series of 536 patients who underwent open radical retropubic ...
Kessler, Thomas M, Schumacher, Martin, Fleischmann, Achim, Studer, Urs E, Burkhard, Fiona C, Thalmann, George N, Studer, Urs, Burkhard FC, Studer, Urs E., Fleischmann A, Kessler, Thomas M., Studer UE, Schumacher M, Burkhard, Fiona Christine, Thalmann GN, Thalmann, George N., Burkhard, Fiona C., Kessler TM, Thalmann, George   +18 more
core   +1 more source

Investigation of Complement Activation and Cytokine Signatures in AQP4+ NMOSD, MOGAD, and MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Aquaporin‐4‐IgG seropositive neuromyelitis optica spectrum disorder (AQP4+ NMOSD), myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), and multiple sclerosis (MS) are pathophysiologically distinct neuroinflammatory disorders. Complement activation is a major mechanism of injury in AQP4+ NMOSD, whereas its role in
Angeliki G. Filippatou, Susana Dominguez‐Penuela, David Acero‐Garces, Georgios Gakis, Matthew D. Smith, Yasmin Resto, Maria Reyes‐Mantilla, Haiwen Chen, Isabella Hernandez, Yana Said, Andrea Salazar‐Camelo, Christina Huynh, Alessia Tassoni, Ted Yednock, Rick Artis, Yaisa Andrews‐Zwilling, Scott D. Newsome, Shiv Saidha, Pavan Bhargava, Ellen M. Mowry, Kathryn C. Fitzgerald, Peter A. Calabresi, Carlos A. Pardo, Elias S. Sotirchos   +23 more
wiley   +1 more source

Nerve-sparing versus non-nerve-sparing radical hysterectomy: surgical and long-term oncological outcomes [PDF]

Oncotarget, 2019
There are controversies regarding the long-term oncological safety of preservation of pelvic innervation during radical hysterectomy (RH). This study aimed to analyze the feasibility and safety of nerve-sparing radical hysterectomy (NSRH) for cervical cancer compared with non-NSRH following 17 years of experience in a tertiary cancer referral center ...
Gil Moreno, Antonio, Carbonell Socias, Melchor, Salicrú Riera, Sabina, Bradbury Lobato, Melissa, García Jiménez, Angel, Vergés Capdevila, Ramona, Puig Puig, Oriol, Sánchez Iglesias, José Luis, Cabrera Diaz, Silvia, De la Torre Fdez de Vega, Fco Javier, Perez Benavente, Maria Asuncion, Rodriguez Gómez-Hidalgo, Natalia, Díaz-Feijoo, Berta   +12 more
openaire   +3 more sources

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Can We Predict the Surgical Margin Positivity in Patients Treated with Radical Prostatectomy? A Multicenter Cohort of Turkish Association of Uro-Oncology

Journal of Urological Surgery, 2015
Objective To analyze the parameters that predict the surgical margin positivity after radical prostatectomy for localized prostate cancer. Materials and Methods In this multicenter study, the data of 1607 consecutive patients undergoing radical ...
Deniz Bolat, Saadettin Eskiçorapcı, Erdem Karabulut, Sümer Baltacı, Asıf Yıldırım, Sinan Sözen, Ferhat Ateş, Çağrı Akın Şekerci, Fatih Kurtuluş, Ayhan Dirim, Talha Muezzioğlu, Cavit Can1, Murat Bozlu, Hakan Gemalmaz, Sinan Ekici1, Haluk Özen, Levent Turkeri   +16 more
doaj   +1 more source

NeuroVisio SyncPatch: A Skin‐Conformal Multimodal EMG–Motion Sensing Platform for Quantitative Neuromuscular Rehabilitation and Performance Monitoring

Advanced Healthcare Materials, EarlyView.
NeuroVisio SyncPatch integrates skin‐conformal electromyography (EMG) electrodes with camera‐tracked markers to jointly assess muscle activity and three‐dimensional knee kinematics during rehabilitation. Parallel feedback pathways provide real‐time kinematic guidance during movement and post‐trial neuromuscular feedback.
Bohyung Choi, Yoo‐Jin Jun, Heewon Choee, Kun‐Do Lee, Heesoo Kim, Yu Seok Hwang, Choong Yeon Kim, Seongok Chae, Juhyun Lee, Minkyu Je, Jae‐Woong Jeong, Hyung‐Soon Park   +11 more
wiley   +1 more source

The best candidates for nerve-sparing stripping surgery for facial nerve schwannoma

, 2014
OBJECTIVES/HYPOTHESIS: Clinical decision making for facial nerve schwannoma is particularly complicated in patients with good facial nerve function; however, an early nerve-sparing tumor resection stripping technique minimizes facial deficits associated ...
이원상, 문인석
core   +1 more source

Impact of mpMRI targeted biopsy on intraoperative nerve‐sparing (NeuroSAFE) during robot‐assisted laparoscopic radical prostatectomy

, 2022
Background The aim of our study was to evaluate the impact of prostate biopsy technique (transrectal ultrasound (US)—prostate biopsy (PBx) versus multiparametric magnetic resonance imaging (mpMRI) targeted prostate biopsy (MRI‐PBx) on intraoperative ...
Trojan, Lutz, Uhlig, Annemarie, Mut, Tuna Till, Leitsmann, Marianne, Popeneciu, Ionel‐Valentin, Ahyai, Sascha, Reichert, Mathias, Bremmer, Felix, Leitsmann, Conrad, Ahyai, Sascha; 1 Department of Urology University Medical Center Goettingen Goettingen Germany, Bremmer, Felix; 2 Department of Pathology University Medical Center Goettingen Goettingen Germany, Leitsmann, Marianne; 1 Department of Urology University Medical Center Goettingen Goettingen Germany, Trojan, Lutz; 1 Department of Urology University Medical Center Goettingen Goettingen Germany, Reichert, Mathias; 1 Department of Urology University Medical Center Goettingen Goettingen Germany, Popeneciu, Ionel‐Valentin; 1 Department of Urology University Medical Center Goettingen Goettingen Germany, Uhlig, Annemarie; 1 Department of Urology University Medical Center Goettingen Goettingen Germany, Mut, Tuna Till; 1 Department of Urology University Medical Center Goettingen Goettingen Germany   +16 more
core   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source