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Inhalational exposure to nerve agents
Respiratory Care Clinics, 2004The respiratory system plays a major role in the pathogenesis of nerve agent toxicity. It is the major route of entry and absorption of nerve agent vapor, and respiratory failure is the most common cause of death follow-ing exposure. Respiratory symptoms are mediated by chemical irritation,muscarinic and nicotinic receptor overstimulation, and central ...
Alexander S, Niven, Stuart A, Roop
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After Salisbury Nerve Agents Revisited
Molecular Informatics, 2018AbstractIn March 2018 the term Novichok (Hoвичoκ) became publically known following an attempted murder of a former Russian spy in Salisbury, UK. Novichok is the name of a group of nerve agents secretly produced by Russia in the later stages of the Cold War.
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Therapy for Nerve Agent Poisoning
Archives of Neurology, 2004Neurologists need to familiarize themselves with nerve agents, the most toxic of the chemical warfare agents. Their mode of action lies within the nervous system, and nonneurologists will look to neurologists for expert advice on therapy. These agents cause rapid-onset cholinergic crisis amenable to prompt treatment with specific antidotes.
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Toxicokinetics of Nerve Agents
2007This chapter presents the subjects as in the second edition, updated with the latest results on the toxicokinetics of VX, mainly obtained after improvement of the analytical methodology. Toxicokinetic studies, together with toxicodynamic studies of nerve agents, provide a quantitative basis for the design of new strategies against intoxication with ...
Marcel J. van der Schans +2 more
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The gut metabolite indole-3 propionate promotes nerve regeneration and repair
Nature, 2022, Guiping Kong, Luming Zhou
exaly