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An Unusual Two‐Step Hydrolysis of Nerve Agents by a Nanozyme
ChemCatChem, 2018Organophosphate‐based nerve agents irreversibly inhibit acetylcholinesterase enzyme, leading to respiratory failure, paralysis and death. Several organophosphorus hydrolases are capable of degrading nerve agents including pesticides and insecticides ...
Kritika Khulbe +3 more
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Therapy for Nerve Agent Poisoning
Archives of Neurology, 2004Neurologists need to familiarize themselves with nerve agents, the most toxic of the chemical warfare agents. Their mode of action lies within the nervous system, and nonneurologists will look to neurologists for expert advice on therapy. These agents cause rapid-onset cholinergic crisis amenable to prompt treatment with specific antidotes.
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Toxicokinetics of Nerve Agents
2007This chapter presents the subjects as in the second edition, updated with the latest results on the toxicokinetics of VX, mainly obtained after improvement of the analytical methodology. Toxicokinetic studies, together with toxicodynamic studies of nerve agents, provide a quantitative basis for the design of new strategies against intoxication with ...
Marcel J. van der Schans +2 more
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Toxicokinetic aspects of nerve agents and vesicants
Handbook of Toxicology of Chemical Warfare Agents, 2020H. John +5 more
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