Results 51 to 60 of about 1,518,769 (304)

Spatial pattern of nerve differentiation in Hydra is due to a pattern of nerve commitment [PDF]

, 1981
The pattern of nerve differentiation along the body column of Hydra was investigated. Nerve precursors in late S phase were labeled with [3H]thymidine and their distribution compared with that of newly differentiated nerves.
G. Venugopal, Venugopal, G., Charles N. David, David, Charles N.   +3 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Research progress of rebound pain after nerve block in arthroscopic rotator cuff repair

Frontiers in Medicine
Arthroscopic rotator cuff repair (ARCR) is a commonly performed surgical intervention for rotator cuff injuries. The advent of ultrasound guidance has facilitated the widespread adoption of nerve blocks as an adjunct anesthetic and analgesic strategy in ...
Xue Yang, Yujiao Yang, Sulan Qin, Yunliang Chen   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comparison of Ilioinguinal/Iliohypogastric Nerve Block and Ilioinguinal/Iliohypogastric Nerve Block Plus Genitofemoral Nerve Block in Patients with Chronic Pelvic/Groin Pain: A Retrospective Quasi-experimental Study [PDF]

Journal of Kerman University of Medical Sciences
Background: Chronic pelvic/groin pain (CP/GP) is a debilitating condition with various treatment options, including nerve blocks. This study aimed to compare the effectiveness of ilioinguinal/iliohypogastric (II/IH) nerve block and the combination of ...
Payman Dadkhah, Mehrdad Taheri, Seyyed Masoud Hashemi, Cyrus Momenzadeh, Jafar Salehi, Keivan Bahrami   +5 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Tetra-block: ultrasound femoral, lateral femoral-cutaneous, obturator, and sciatic nerve blocks in lower limb anesthesia: a case series

Journal of Medical Case Reports, 2023
Background The gold standard anesthesiologic procedure for urgent femur fracture surgery is Spinal Anesthesia. It is not always feasible because of patients' severe comorbidities and difficulties in optimizing drug therapy in the appropriate time frame ...
Antonio Coviello, Carmine Iacovazzo, Dario Cirillo, Pasquale Diglio, Alessio Bernasconi, Andrea Cozzolino, Antonio Izzo, Annachiara Marra, Giuseppe Servillo, Maria Vargas   +9 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Glucose availability and sensitivity to anoxia of isolated rat peripheral nerve [PDF]

, 1991
The contrast between resistance to ischemia and ischemic lesions in peripheral nerves of diabetic patients was explored by in vitro experiments. Isolated and desheathed rat peroneal nerves were incubated in the following solutions with different glucose ...
R. Jund, U. Schneider, Schneider, Uwe, P. Grafe, Strupp, Michael, Jund, R., Grafe, Peter, M. Strupp   +7 more
core   +1 more source

Achilles hero or heel? A systematic review of popliteal nerve block for achilles repair

Foot & Ankle Surgery: Techniques, Reports & Cases
Achilles tendon rupture is an exceptionally common injury, particularly among athletes. Popliteal nerve block is often performed for pain relief during surgical Achilles repair; however, the evidence basis demonstrating its analgesic effectiveness is ...
Connor T.A. Brenna, MD, Shawn Khan, MD MEng, Faraj W. Abdallah, MD FRCPC, Richard Brull, MD FRCPC   +3 more
doaj   +1 more source