Ultrasound-Guided Sural Nerve and Tibial Nerve Block Provides Comparable Analgesia to Popliteal Sciatic Nerve Block Following Calcaneal Surgery: A Single Center Randomized Controlled Double-Blind Study [PDF]
Jun Yao,1,2,* Jialin Cai,2,* Qingwang Lu,2 Xiaojing Huang3 1Department of Anesthesiology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, 200233, People’s Republic of China; 2Department of Anesthesiology, Jinjiang ...
Yao J, Huang X, Cai J, Lu Q
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FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
, 2009 BACKGROUND AND OBJECTIVES: Nerve blocks using local anesthetics are widely used. High volumes are usually injected, which may predispose patients to associated adverse events.
Willimann, P +17 more
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The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]
, 1993 Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Niedermeier, W. +2 more
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FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Asymmetric tripolar nerve cuff electrode designs for optimizing anodal block of myelinated fibers
BioMedical Engineering OnLinePurpose Anodal block is a common mechanism used to generate unidirectional activation of myelinated nerve fibers. However, nerve block is often inconsistent and difficult to achieve.
Daniel Tovbis +3 more
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
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The use of local anesthesia and nerve blocks for scrotal and penile surgery: Local anaesthesia for scrotal and penile surgery [PDF]
Serbian Journal of Anesthesia and Intensive TherapyLocal anaesthetics are widely used for penile and genital surgery, with techniques tailored to the specific nerve supply and dermatomal distribution of the genitalia.
Lađević Nikola +5 more
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Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Effects of median nerve block on radial artery diameter and peak velocity
, 2010 John J Badal, Annie Kiesau, Patrick BoyleUniversity of Arizona, Department of Anesthesiology, Tucson, AZ, USAAbstract: Peripheral artery cannulation is a common procedure but can sometimes be difficult.
Annie Kiesau +2 more
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