Results 61 to 70 of about 436,772 (306)

Local anesthesia for transurethral manipulations: is a transrectal periprostatic nerve block effective? [PDF]

, 2018
Periprostatic nerve block has been reported to be an effective form of anesthesia for prostatic surgery. Recent studies have shown the simplicity and the efficacy of a transrectal approach for periprostatic nerve block.
Fatzer, Markus, John, Hubert, Müntener, Michael, Praz, Valentin, Straumann, Urs, Strebel, Räto   +5 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Ultrasound-Guided Femoral and Sciatic Nerve Blocks for Repair of Tibia and Fibula Fractures in a Bennett's Wallaby (Macropus rufogriseus) [PDF]

, 2016
Locoregional anesthetic techniques may be a very useful tool for the anesthetic management of wallabies with injuries of the pelvic limbs and may help to prevent capture myopathies resulting from stress and systemic opioids’ administration.
Adami, C, Campoy, L, Monticelli, P
core   +5 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Achilles hero or heel? A systematic review of popliteal nerve block for achilles repair

Foot & Ankle Surgery: Techniques, Reports & Cases
Achilles tendon rupture is an exceptionally common injury, particularly among athletes. Popliteal nerve block is often performed for pain relief during surgical Achilles repair; however, the evidence basis demonstrating its analgesic effectiveness is ...
Connor T.A. Brenna, MD, Shawn Khan, MD MEng, Faraj W. Abdallah, MD FRCPC, Richard Brull, MD FRCPC   +3 more
doaj   +1 more source

The Femoral Nerve Block Setting the Agenda for Nursing Care of Older Patients With hip Fractures—A Qualitative Study

SAGE Open Nursing, 2023
Introduction Hip fractures among older people are common worldwide, and it is often associated with preoperative pain. Due to increased comorbidity and high age, traditional pain relief can be a challenge.
Anna Unneby RN, PhD, Birgitta Olofsson RN, PhD, Britt-Marie Lindgren RN, PhD   +2 more
doaj   +1 more source

Conduction block in acute motor axonal neuropathy [PDF]

, 2017
Guillain-Barré syndrome is divided into two major subtypes, acute inflammatory demyelinating polyneuropathy and acute motor axonal neuropathy. The characteristic electrophysiological features of acute motor axonal neuropathy are reduced amplitude or ...
Hirata, Koichi, Kokubun, Norito, Nishibayashi, Momoka, Odaka, Masaaki, Uncini, Antonino, Yuki, Nobuhiro   +5 more
core  

A pragmatic randomised controlled trial comparing the efficacy of a femoral nerve block and periarticular infiltration for early pain relief following total knee arthroplasty [PDF]

, 2017
Aims The aim of this study was to compare the effectiveness of a femoral nerve block and a periarticular infiltration in the management of early post-operative pain after total knee arthroplasty (TKA).
Achten, Juul, Balasubramanian, S., Costa, Matthew L., Parsons, Helen, Parsons, Nicholas R., Sprowson, A. P., Thompson, P., Wall, Peter D. H.   +7 more
core   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

A cadaveric study comparing the three approaches for ulnar nerve block at wrist

Saudi Journal of Anaesthesia, 2014
Background: Ulnar nerve blockade as a component of wrist block is a promising technique for adequate anesthesia and analgesia for different surgeries of the hand. Due to anatomical variations in the location of ulnar nerve under the flexor carpi ulnaris (
Rohit Varshney, Nidhi Sharma, Shraddha Malik, Sunny Malik   +3 more
doaj   +1 more source