Results 61 to 70 of about 3,192,615 (314)

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

The Femoral Nerve Block Setting the Agenda for Nursing Care of Older Patients With hip Fractures—A Qualitative Study

SAGE Open Nursing, 2023
Introduction Hip fractures among older people are common worldwide, and it is often associated with preoperative pain. Due to increased comorbidity and high age, traditional pain relief can be a challenge.
Anna Unneby RN, PhD, Birgitta Olofsson RN, PhD, Britt-Marie Lindgren RN, PhD   +2 more
doaj   +1 more source

Dexamethasone as Adjuvant to Bupivacaine Prolongs the Duration of Thermal Antinociception and Prevents Bupivacaine-Induced Rebound Hyperalgesia via Regional Mechanism in a Mouse Sciatic Nerve Block Model

PLoS ONE, 2015
Background Dexamethasone has been studied as an effective adjuvant to prolong the analgesia duration of local anesthetics in peripheral nerve block. However, the route of action for dexamethasone and its potential neurotoxicity are still unclear. Methods
K. An, N. Elkassabany, Jiabin Liu
semanticscholar   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

A cadaveric study comparing the three approaches for ulnar nerve block at wrist

Saudi Journal of Anaesthesia, 2014
Background: Ulnar nerve blockade as a component of wrist block is a promising technique for adequate anesthesia and analgesia for different surgeries of the hand. Due to anatomical variations in the location of ulnar nerve under the flexor carpi ulnaris (
Rohit Varshney, Nidhi Sharma, Shraddha Malik, Sunny Malik   +3 more
doaj   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Tetra-block: ultrasound femoral, lateral femoral-cutaneous, obturator, and sciatic nerve blocks in lower limb anesthesia: a case series

Journal of Medical Case Reports, 2023
Background The gold standard anesthesiologic procedure for urgent femur fracture surgery is Spinal Anesthesia. It is not always feasible because of patients' severe comorbidities and difficulties in optimizing drug therapy in the appropriate time frame ...
Antonio Coviello, Carmine Iacovazzo, Dario Cirillo, Pasquale Diglio, Alessio Bernasconi, Andrea Cozzolino, Antonio Izzo, Annachiara Marra, Giuseppe Servillo, Maria Vargas   +9 more
doaj   +1 more source

Retracted: Effect of Ropivacaine‐Loaded Magnetic Nanoparticles on Ankle Nerve Block in Rats [PDF]

, 2023
Computational and Mathematical Methods in Medicine
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

The use of local anesthesia and nerve blocks for scrotal and penile surgery: Local anaesthesia for scrotal and penile surgery [PDF]

Serbian Journal of Anesthesia and Intensive Therapy
Local anaesthetics are widely used for penile and genital surgery, with techniques tailored to the specific nerve supply and dermatomal distribution of the genitalia.
Lađević Nikola, Petrović Nataša, Jovičić Jelena, Jovanović Vesna, Lazić Miloš, Dimić Nemanja   +5 more
doaj   +1 more source