Results 261 to 270 of about 44,817 (303)

Nerve Crush???A Possible Treatment of Peripheral Neuralgia

Survey of Anesthesiology, 1987
Twenty-three patients with neuralgic pain (mean duration 3 years) were treated with crushing instead of sectioning the peripheral nerve. There was immediate relief of pain in 19 patients (83%). With the return of skin sensation the pain recurred after 3-4 months in 4 patients and within 2.5 years in another 3 patients. Twelve (52%) of the patients felt
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Effects of nerve growth factor on crushed sciatic nerve regeneration in rats

Microsurgery, 1995
AbstractThe effects of nerve growth factor (NGF) on crushed sciatic nerve regeneration were studied in 30 rats, with 60 bilateral nerves. The nerves were crushed at a site 6 mm distal to the sciatic notch by the standard technique and 3 mm wide crush injuries were created.
Z W, Chen, M S, Wang
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Peripheral Nerve Crush inDrosophilaLarvae

Cold Spring Harbor Protocols
The long length of axons makes them vulnerable to damage; hence, it is logical that nervous systems have evolved adaptive mechanisms for responding to axon damage. Studies inDrosophila melanogasterhave identified evolutionarily conserved molecular pathways that enable axonal degeneration and regeneration of damaged axons and/or dendrites. This protocol
Thomas J, Waller, Laura J, Smithson, Catherine A, Collins   +2 more
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Protective effect of paeoniflorin against optic nerve crush

Journal of Huazhong University of Science and Technology [Medical Sciences], 2007
In order to evaluate the efficacy of traditional paeonia extract paeoniflorin against optic nerve crush, 16 Brown Norway rats were divided into two groups at random, with 8 rats in each group. In paeoniaflorin-treated group, 2 mg paeoniaflorin (total volume: 1 mL) was injected into rat's peritoneum one time a day for a period of 8 days.
Jing, Li, Xinchun, Xiong, Yunhai, Liu
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Delivery of an Adenoviral Vector to the Crushed Recurrent Laryngeal Nerve

The Laryngoscope, 2003
AbstractObjectives Objectives were to create a model of recurrent laryngeal nerve injury for testing the efficacy of potential therapeutic viral gene therapy vectors and to demonstrate that remote injection of a viral vector does not cause significant additional neuronal injury.Study Design Animal model.Methods Rats were randomly assigned to three ...
Adam, Rubin, Bret, Mobley, Norman, Hogikyan, Kimberly, Bell, Kelli, Sullivan, Nicholas, Boulis, Eva, Feldman   +6 more
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Reactive Fibroblasts in Response to Optic Nerve Crush Injury

Molecular Neurobiology, 2020
Traumatic optic neuropathy leads to bidirectional degeneration of retinal ganglion cells and axons and results in optic nerve scaring, which inhibits the regeneration of damaged axons. Compared with its glial counterpart, the fibrotic response causing nerve scar tissue is poorly permissive to axonal regeneration. Using collagen1α1-GFP reporter mice, we
Xiangxiang Liu, Yuan Liu, Huiyi Jin, Mohamed M. Khodeiry, Weizheng Kong, Ningli Wang, Jae K. Lee, Richard K. Lee   +7 more
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Reinnervation of cat pacinian corpuscles after nerve crush

Acta Neuropathologica, 1997
The reinnervation pattern of crural pacinian corpuscles was examined by light and electron microscopy in eight adult cats of both sexes 3-18 months after sciatic nerve crush. Normal pacinian corpuscles are each supplied with a single myelinated axon and a single cylindrical axon terminal which may branch in the distal part of the inner core ...
J, Zelená, G, Zacharová
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A Rat Model for Intracranial Facial Nerve Crush Injuries

Otolaryngology–Head and Neck Surgery, 2011
Objective(1) Explain the need for an animal model to study intracranial injuries to the facial nerve. (2) Describe various techniques attempted to identify and crush the intracranial segment of the facial nerve in a rat model. (3) Describe in detail a successful rat model of intracranial facial nerve crush injury.Study DesignRandomized controlled ...
Ryan C, Burgette, Brent J, Benscoter, Gina N, Monaco, Matthew L, Kircher, Avinash V, Mantravadi, Sam J, Marzo, Kathy J, Jones, Eileen M, Foecking   +7 more
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Chronic Nerve Compression Model for the Double Crush Hypothesis

Annals of Plastic Surgery, 1991
"Double crush hypothesis" is a phrase that has entered clinical use based on a hypothesis presented by Upton and McComas in 1973. Although clinical examples of the double crush are appearing more frequently, there has been no experimental proof of this hypothesis as it relates to chronic nerve compression.
A L, Dellon, S E, Mackinnon
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Single vs multiple somatic nerve crushes in the rat

Brain Research, 1987
Nerve lesions modify regenerative responses to subsequent lesions. Some of the modifications might be useful. To increase our understanding of these modifications, the present study determines myelinated and unmyelinated axon numbers in the distal part of rat sciatic nerve and in 2 smaller branches, the nerve to the medial gastrocnemius muscle and the ...
C B, Jenq, R E, Coggeshall
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