Results 121 to 130 of about 113,844 (214)

A quantitative evaluation of gross versus histologic neuroma formation in a rabbit forelimb amputation model: potential implications for the operative treatment and study of neuromas

open access: yesJournal of Brachial Plexus and Peripheral Nerve Injury, 2011
Background Surgical treatment of neuromas involves excision of neuromas proximally to the level of grossly "normal" fascicles; however, proximal changes at the axonal level may have both functional and therapeutic implications with regard to amputated ...
Kuiken Todd A   +5 more
doaj   +1 more source

Intrinsic dynamical fluctuations of PNS myelin [PDF]

open access: yesarXiv, 2017
The ultrastructure fluctuations and complex dynamics of the multi-layered membrane structure of myelin are fundamental for understanding and control its formation process and its degeneration and repair in neurological diseases such as multiple sclerosis (MS).
arxiv  

Tumor microenvironment (Part I): Tissue integrity in a rat model of peripheral neural cancer [PDF]

open access: yesHeliyon, Volume 10, Issue 13, e33932, July 15, 2024
ICAM-1 (intercellular adhesion molecule 1) and MPZ (myelin protein zero) are thought to be a factor in the integrity of nerve tissues. In this report, we attempted to trace the expression of ICAM-1, responsible for cell-to-cell adhesion, and of MPZ, the main constituent of myelin sheath, in malignant tissues of the sciatic nerve (SN) in inbred male ...
arxiv   +1 more source

Quantitative T1 is sensitive to cortical remyelination in multiple sclerosis: A postmortem MRI study

open access: yesBrain Pathology, EarlyView.
In a post‐mortem study using multiparametric qMRI of whole fixed human brains from people with multiple sclerosis (pwMS), we found evidence that quantitative T1 (qT1) is sensitive to remyelination in the cortex. In contrast, QSM and radial diffusivity were affected by cortical pathology independently of remyelination. Our data suggest that qT1 could be
Riccardo Galbusera   +14 more
wiley   +1 more source

Cell vibron polariton in the myelin sheath of nerve [PDF]

open access: yesarXiv, 2019
Polaritons are arousing tremendous interests in physics and material sciences for their unique and amazing properties, especially including the condensation, lasing without inversion and even room-temperature superfluidity. Herein, we propose a cell vibron polariton (cell-VP): a collectively coherent mode of a photon and all phospholipid molecules in a
arxiv  

Regenerating Locus Coeruleus‐Norepinephrine (LC‐NE) Function: A Novel Approach for Neurodegenerative Diseases

open access: yesCell Proliferation, EarlyView.
The regeneration of LC‐NE from pluripotent stem cells (PSCs) could significantly mitigate the progression of Neurodegenerative diseases and alleviate associated psychiatric disease symptoms, providing a new approach to the treatment of neurological diseases.
Yana Yang, Yunlong Tao
wiley   +1 more source

Quantitative Ultrasound and B-mode Image Texture Features Correlate with Collagen and Myelin Content in Human Ulnar Nerve Fascicles [PDF]

open access: yesarXiv, 2019
We investigate the usefulness of quantitative ultrasound (QUS) and B-mode texture features for characterization of ulnar nerve fascicles. Ultrasound data were acquired from cadaveric specimens using a nominal 30 MHz probe. Next, the nerves were extracted to prepare histology sections.
arxiv  

Exercise Delays Brain Ageing Through Muscle‐Brain Crosstalk

open access: yesCell Proliferation, EarlyView.
This graphical abstract illustrates the reciprocal crosstalk between the brain and peripheral organs, highlighting the profound impact of exercise on brain health through systemic interactions. It underscores how exercise influences the brain via signals from various organs and, conversely, how the brain modulates functions of peripheral organs.
Shirin Pourteymour   +3 more
wiley   +1 more source

THE EFFECTS OF NERVE GROWTH FACTOR ON MYELINATION OF REGENERATED FIBERS IN RAT [PDF]

open access: yesActa Medica Iranica, 2003
The effect of nerve growth factor (NGF) on regeneration of rat sciatic nerves in adult rat was studied. The sciatic nerve was cut out across a 6‑mm gap, then the proximal and distal stumps were inserted into the silicone tube chamber.
M. Firouzi
doaj   +1 more source

Specific Iron Binding to Natural Sphingomyelin Membrane Induced by Non-Specific Co-Solutes [PDF]

open access: yes
Hypothesis: Sphingomyelin (SPM), a crucial phospholipid in the myelin sheath, is vital in insulating nerve fibers. We hypothesize that iron ions selectively bind to the phosphatidylcholine (PC) template within the SPM membrane under near-physiological conditions, disrupting membrane organization.
arxiv   +1 more source

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