Results 131 to 140 of about 39,698 (257)
Combinatorial targeting of MYC/BCL2‐associated vulnerabilities in high‐grade B‐cell lymphoma
British Journal of Haematology, EarlyView.
Giulio Donati +6 more
wiley +1 more source
Women in space: A review of known physiological adaptations and health perspectives
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford +4 more
wiley +1 more source
Glial cells in the heart: Implications for their roles in health and disease
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya +2 more
wiley +1 more source
Automated Quantitative Analysis of Nerve Fiber Conduction Velocity [PDF]
poster abstractThe baroreflex (BRX) is essential for reliable autonomic control of arterial blood pressure. Central to BRX function is a rapid, negative feedback control of heart rate.
Haas, Kyle D. +2 more
core
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil +11 more
wiley +1 more source
CDC42‐Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity
CDC42‐effector proteins 1/2 are present in CNS myelin. They facilitate the higher order structure of myelin septin filaments. Their loss impairs septin‐dependent scaffolding of myelin. Myelin outfoldings do not cause secondary neuropathology per se. ABSTRACT The regular structure of CNS myelin requires specialized structural proteins, including septin ...
Sophie Hümmert +14 more
wiley +1 more source
ABSTRACT Purpose The IEC 60601‐2‐33 standard provides consensus‐based safety provisions for MRI equipment. Protection of patients against cardiac stimulation (CS) is based on limiting the maximum E‐field induced by MRI gradient coils. In practice, this is achieved by imposing a conservative dB/dt threshold on any gradient waveform.
Valerie Klein +9 more
wiley +1 more source
ABSTRACT Background and Aims In individuals with hereditary transthyretin amyloidosis (ATTRv) polyneuropathy, monitoring of disease progression and treatment response is crucial. The objective is to determine if serum neurofilament light chain (sNfL) and serum glial fibrillary acidic protein (sGFAP) are reliable biomarkers of ATTRv polyneuropathy ...
Valentin Loser +9 more
wiley +1 more source
Various sodium channel isoforms and their scaffolding proteins are found in four different microdomains in vestibular calyx‐bearing afferents. These microdomains serve different purposes, analogous to the heminode, axon initial segment, and synaptic domains of other types of sensory afferents.
Anna Lysakowski +8 more
wiley +1 more source

