Results 171 to 180 of about 113,844 (214)

The Fragile X Messenger Ribonucleoprotein 1 Regulates the Morphology and Maturation of Human and Rat Oligodendrocytes

Glia, Volume 73, Issue 6, Page 1203-1220, June 2025.
Main Points Loss of FMRP impairs human and rat oligodendrocyte (OL) morphology in vitro. FMRP‐deficient OLs show impaired maturation when engrafted in hypomyelinated mice. Rat Fmr1 knockout OLs show a delay in myelin sheath formation in vivo. ABSTRACT The Fragile X Messenger Ribonucleoprotein (FMRP) is an RNA binding protein that regulates the ...
Vidya Ramesh, Eleni Tsoukala, Ioanna Kougianou, Zrinko Kozic, Karen Burr, Biju Viswanath, David Hampton, David Story, Bharath Kumar Reddy, Rakhi Pal, Owen Dando, Peter C. Kind, Sumantra Chattarji, Bhuvaneish T. Selvaraj, Siddharthan Chandran, Lida Zoupi   +15 more
wiley   +1 more source

The Role of Proton Magnetic Resonance Spectroscopy in Neonatal and Fetal Brain Research

Journal of Magnetic Resonance Imaging, Volume 61, Issue 6, Page 2404-2424, June 2025.
The biochemical composition and structure of the brain are in a rapid change during the exuberant stage of fetal and neonatal development. 1H‐MRS is a noninvasive tool that can evaluate brain metabolites in healthy fetuses and infants as well as those with neurological diseases.
Steve C.N. Hui, Nickie Andescavage, Catherine Limperopoulos   +2 more
wiley   +1 more source

Considerations and recommendations from the ISMRM diffusion study group for preclinical diffusion MRI: Part 1: In vivo small‐animal imaging

Magnetic Resonance in Medicine, Volume 93, Issue 6, Page 2507-2534, June 2025.
Abstract Small‐animal diffusion MRI (dMRI) has been used for methodological development and validation, characterizing the biological basis of diffusion phenomena, and comparative anatomy. The steps from animal setup and monitoring, to acquisition, analysis, and interpretation are complex, with many decisions that may ultimately affect what questions ...
Ileana O. Jelescu, Francesco Grussu, Andrada Ianus, Brian Hansen, Rachel L. C. Barrett, Manisha Aggarwal, Stijn Michielse, Fatima Nasrallah, Warda Syeda, Nian Wang, Jelle Veraart, Alard Roebroeck, Andrew F. Bagdasarian, Cornelius Eichner, Farshid Sepehrband, Jan Zimmermann, Lucas Soustelle, Christien Bowman, Benjamin C. Tendler, Andreea Hertanu, Ben Jeurissen, Marleen Verhoye, Lucio Frydman, Yohan van de Looij, David Hike, Jeff F. Dunn, Karla Miller, Bennett A. Landman, Noam Shemesh, Adam Anderson, Emilie McKinnon, Shawna Farquharson, Flavio Dell'Acqua, Carlo Pierpaoli, Ivana Drobnjak, Alexander Leemans, Kevin D. Harkins, Maxime Descoteaux, Duan Xu, Hao Huang, Mathieu D. Santin, Samuel C. Grant, Andre Obenaus, Gene S. Kim, Dan Wu, Denis Le Bihan, Stephen J. Blackband, Luisa Ciobanu, Els Fieremans, Ruiliang Bai, Trygve B. Leergaard, Jiangyang Zhang, Tim B. Dyrby, G. Allan Johnson, Julien Cohen‐Adad, Matthew D. Budde, Kurt G. Schilling   +56 more
wiley   +1 more source

Diffusion tensor subspace imaging of double diffusion–encoded MRI delineates small fibers and gray‐matter microstructure not visible with single encoding techniques

Magnetic Resonance in Medicine, Volume 93, Issue 6, Page 2370-2385, June 2025.
Abstract Purpose Double diffusion encoding (DDE) acquisition strategies promise specificity for small‐dimensional structures inaccessible to single diffusion encoding (SDE). For DDE‐weighted MRI scans to become relevant for whole brain imaging, signal reconstruction frameworks must accurately report microstructural features of interest—especially ...
Elizabeth B. Hutchinson, Jean‐Philippe Galons, Courtney J. Comrie, Thomas G. Beach, Geidy E. Serrano, Mark W. Bondi, Seraphina K. Solders, Vitaly L. Galinsky, Lawrence R. Frank   +8 more
wiley   +1 more source

Sensory Nerve Action Potential Analysis in a Cohort of Patients With Spinal Muscular Atrophy Aged 12 Years and Older

Muscle &Nerve, Volume 71, Issue 6, Page 1016-1024, June 2025.
ABSTRACT Introduction/Aims Survival Motor Neuron 1 (SMN1)‐related spinal muscular atrophy (SMA) is characterized by α‐motor neuron degeneration, with sensory function assumed to be clinically preserved. However, recent studies in severely affected patients and animal models have challenged this view.
Leandra A. A. Ros, Boudewijn T. H. M. Sleutjes, H. Stephan Goedee, Fay‐Lynn Asselman, Inge Cuppen, Ruben P. A. van Eijk, W. Ludo van der Pol, Renske I. Wadman   +7 more
wiley   +1 more source

New Approaches Based on Serial‐Block Face Electron Microscopy to Investigate the Peripheral Nervous System

Journal of the Peripheral Nervous System, Volume 30, Issue 2, June 2025.
ABSTRACT Background and Aims Serial block face scanning electron microscopy (SBF‐SEM) enables automated 3D imaging of specimens with ultrastructural resolution. However, its application is often restricted due to the complex and labor‐intensive nature of the processes involved.
Vitalijs Borisovs, Mario Bossi, Laura Matino, Paola Marmiroli, Guido Cavaletti   +4 more
wiley   +1 more source

Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination [PDF]

, 2017
et al.,, Mogha, Amit, Monk, Kelly
core   +1 more source

GPR56/ADGRG1 regulates development and maintenance of peripheral myelin [PDF]

, 2018
Ackerman, Sarah D, D\u27Rozario, Mitchell, et al,, Gamble, Paul, Harty, Breanne L, MacEwan, Matthew R, Mogha, Amit, Monk, Kelly R, Ray, Wilson Zachary, Sanchez, Nicholas E   +9 more
core   +1 more source

Differential regulation of bladder pain and voiding function by sensory afferent populations revealed by selective optogenetic activation [PDF]

, 2010
DeBerry, Jennifer J, Samineni, Vijay K, Copits, Bryan A, Sullivan, Christopher J, Vogt, Sherri K, Albers, Kathryn M, Davis, Brian M, Gereau, Robert W, IV   +7 more
core   +1 more source

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Differential involvement of myelinated and unmyelinated nerve fibers in painful diabetic polyneuropathy

Muscle and Nerve, 2020
We aimed at evaluating the differential involvement of large myelinated Aβ‐, small myelinated Aδ‐, and unmyelinated C‐fibers in patients with diabetic polyneuropathy and how they contribute to neuropathic pain.
E. Galosi, G. di Pietro, S. La Cesa, G. Di Stefano, C. Leone, A. Fasolino, A. Di Lionardo, F. Leonetti, R. Buzzetti, C. Mollica, G. Cruccu, A. Truini   +11 more
semanticscholar   +1 more source