Acta Dermato-Venereologica, 2019 Prurigo nodularis is a highly pruritic and hyperplastic chronic dermatosis with unknown pathogenesis. Many pruritogenic mediators, including nerve growth factor, interleukin (IL)-31, thymic stromal lymphopoietin, and endothelin-1, are implicated in ...
Weilong Zhong +9 more
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Production of a Monoclonal Antibody Directed against the High-Affinity Nerve Growth Factor Receptor
The International Journal of Biological Markers, 1999 The high-affinity nerve growth factor receptor corresponds to the tyrosine protein kinase encoded by the proto-oncogene trkA. Different findings suggest that nerve growth factor (NGF) can be operative in the growth modulation of tumor cell lines ...
E. Tagliabue +8 more
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Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways. [PDF]
, 2016 Tissue injury, whether by trauma, surgical intervention, metabolic dysfunction, ischemia, or infection, evokes a complex cellular response (inflammation) that is associated with painful hyperalgesic states.
Guan, Zhonghui +2 more
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Biodegradable magnesium wire promotes regeneration of compressed sciatic nerves
Neural Regeneration Research, 2016 Magnesium (Mg) wire has been shown to be biodegradable and have anti-inflammatory properties. It can induce Schwann cells to secrete nerve growth factor and promote the regeneration of nerve axons after central nervous system injury. We hypothesized that
Bo-han Li, Ke Yang, Xiao Wang
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ProNGF-p75NTR axis plays a proinflammatory role in inflamed joints. A novel pathogenic mechanism in chronic arthritis [PDF]
, 2017 To identify the role of mature nerve growth factor (mNGF), its immature form proNGF and their receptors in arthritis ...
Benedetti, Fabrizio De +9 more
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Neural Regeneration Research, 2016 Delayed ischemic neurologic deficit after subarachnoid hemorrhage results from loss of neural cells. Nerve growth factor and its receptor TrkA may promote regeneration of neural cells, but their expression after subarachnoid hemorrhage remains unclear ...
Jin-ning Song +6 more
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Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A). [PDF]
PLoS Pathogens, 2013 Botulinum neurotoxin serotype A (BoNT/A) causes transient muscle paralysis by entering motor nerve terminals (MNTs) where it cleaves the SNARE protein Synaptosomal-associated protein 25 (SNAP25206) to yield SNAP25197.
Birgitte P S Jacky +12 more
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Nerve Growth Factor Receptor-Mediated Gene Transfer
Molecular Therapy, 2004 One obstacle to effective gene therapies for neurological disorders lies in the cell-type diversity of the nervous system, making it difficult to direct gene delivery vectors to specific types of cells. To meet this challenge, we have developed a recombinant peptide-based gene delivery vector that targets nerve growth factor (NGF) receptors.
Ma, N. +7 more
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Both P140TRK and P75NGFR nerve growth factor receptors mediate nerve growth factor-stimulated calcium uptake [PDF]
Neuroscience Letters, 1997 Human p140(trk) and p75(NGFR) were transfected separately into 3T3 cells. Nerve growth factor stimulates calcium uptake into both transfectants but not into untransfected 3T3 cells. p140(trk) cells were stimulated maximally by 25 ng/ml; 100 ng/ml was submaximal for p75(NGFR) cells.
H, Jiang +6 more
openaire +2 more sources
Nerve growth factor, brain-derived neurotrophic factor, and the chronobiology of mood: a new insight into the "neurotrophic hypothesis" [PDF]
, 2015 The light information pathways and their relationship with the body rhythms have generated a new insight into the neurobiology and the neurobehavioral sciences, as well as into the clinical approaches to human diseases associated with disruption of ...
IANNITELLI, ANGELA +2 more
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