Results 311 to 320 of about 286,784 (355)
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Nerve Growth Factor Receptors in Human Neuroblastoma Cells
Journal of Neurochemistry, 1987AbstractReceptors for the nerve growth factor protein (NGFR) present in the human neuroblastoma cell line LAN‐1 were characterized. LAN‐1 cells display high‐affinity (type I, with KD value of 5.9 × 10‐11M) and low‐affinity (type II, with KD value of 9.2 × 10‐9M) binding to NGF.
D, Marchetti, J R, Perez-Polo
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Characteristics of Partially Purified Nerve Growth Factor Receptor
Journal of Neurochemistry, 1987Abstract: Receptors for the nerve growth factor protein (NGF) have been isolated from three cell types [embryonic chicken sensory neurons (dorsal root sensory ganglia; DRG), rat pheochromocytoma (PC 12) and human neuroblastoma (LAN‐1) cells] and have been shown to be similar with respect to equilibrium dissociation constants.
R W, Stach, C R, Lyons, J R, Perez-Polo
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Journal of Neuroscience Research, 1992
AbstractGlucocorticoids and nerve growth factor (NGF) have been shown to have antagonistic effects on chromaffin cells in vivo. Here we determined the effect of the synthetic glucocorticoid, dexamethasone, on levels of mRNA for the nerve growth factor receptor (NGFR) in rat PC12 pheochromocytoma cells.
P J, Foreman +3 more
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AbstractGlucocorticoids and nerve growth factor (NGF) have been shown to have antagonistic effects on chromaffin cells in vivo. Here we determined the effect of the synthetic glucocorticoid, dexamethasone, on levels of mRNA for the nerve growth factor receptor (NGFR) in rat PC12 pheochromocytoma cells.
P J, Foreman +3 more
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Tissue Localization of Nerve Growth Factor and Nerve Growth Factor Receptors
1991The pioneering investigations of Levi-Montalcini and coworkers established that nerve growth factor (NGF) is an important physiological regulator of neurons of the peripheral nervous system. No doubt in part because of the dramatic and specific effects on the sympathetic and sensory nervous system resulting from immunochemically depriving rodents of ...
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Expression of nerve growth factor receptor during human peripheral nerve development
Developmental Biology, 1988The expression of NGF receptors on human Schwann cells during development and myelination and in culture was analyzed using a murine monoclonal antibody to human NGF receptor. Nonmyelinated femoral nerves from 13- to 14-week fetuses stained strongly for NGF receptor, whereas tissues from later stages of development showed a decrease in the staining ...
E, Scarpini +6 more
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Journal of Neurochemistry, 1987
Abstract: We have used biologically active derivatives of β‐nerve growth factor (NGF), modified by biotinylation via carboxyl groups, to target the specific binding of liposomes to cultured rat and human tumor cells bearing NGF receptors. Liposomes, to be used for targeting, were prepared by conjugating streptavidin to phospholipid amino groups on ...
M B, Rosenberg +2 more
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Abstract: We have used biologically active derivatives of β‐nerve growth factor (NGF), modified by biotinylation via carboxyl groups, to target the specific binding of liposomes to cultured rat and human tumor cells bearing NGF receptors. Liposomes, to be used for targeting, were prepared by conjugating streptavidin to phospholipid amino groups on ...
M B, Rosenberg +2 more
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European Journal of Oral Sciences, 2012
Nerve growth factor (NGF) is a pluripotent mediator that is present in a range of human tissues. Nerve growth factor was originally considered important only in neuronal homeostasis and pathophysiology, but later it was also implicated in the pathophysiology of inflammation, epithelial differentiation, and wound healing. In this study, the distribution
Elsebeth P, Naesse +4 more
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Nerve growth factor (NGF) is a pluripotent mediator that is present in a range of human tissues. Nerve growth factor was originally considered important only in neuronal homeostasis and pathophysiology, but later it was also implicated in the pathophysiology of inflammation, epithelial differentiation, and wound healing. In this study, the distribution
Elsebeth P, Naesse +4 more
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Nerve growth factor receptor role on rabbit sperm storage
Theriogenology, 2020The influence of NGF in male reproduction in some animal species and humans has already been assessed. Many of these effects are mediated by the distribution and abundance of tropomyosin receptor kinase A (TrKA) and p75 neurotrophin (p75NTR) receptors on sperm cells.
Cesare, Castellini +7 more
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The Membrane Receptor for Nerve Growth Factor
1991Receptors for mammalian growth factors are integral membrane proteins designed to have multiple functions for communicating with other cells and for intracellular signal transduction. These cell surface proteins have binding sites for the ligand that face the external environment and also an effector site that generates a biological signal within the ...
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European Journal of Neuroscience, 1990
AbstractSensory neurons of the adult rat dorsal root ganglion (DRG) can be maintained in culture in the absence of nerve growth factor (NGF). We have thus used dissociated cultures of these neurons to study effects of NGF on the regulation of expression of mRNA encoding the nerve growth factor receptor (NGF‐R).
R. M., Lindsay +6 more
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AbstractSensory neurons of the adult rat dorsal root ganglion (DRG) can be maintained in culture in the absence of nerve growth factor (NGF). We have thus used dissociated cultures of these neurons to study effects of NGF on the regulation of expression of mRNA encoding the nerve growth factor receptor (NGF‐R).
R. M., Lindsay +6 more
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