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Breast cancer represents the most common type of cancer and is the leading cause of death due to cancer among women. Thus, the prevention and early diagnosis of breast cancer is of primary urgency, as well as the development of new treatments able to ...
Francesco Bruno +5 more
doaj +1 more source
Signalling mechanisms of long term facilitation of breathing with intermittent hypoxia. [PDF]
Intermittent hypoxia causes long-term facilitation (LTF) of respiratory motor nerve activity and ventilation, which manifests as a persistent increase over the normoxic baseline for an hour or more after the acute hypoxic ventilatory response.
Pamenter, Matthew E, Powell, Frank L
core +1 more source
The chemoattractant receptor–homologous molecule expressed on T-helper type 2 cells (CRTH2) is the most recently identified prostaglandin (PG) receptor for both PGD2 and 15-deoxy-Δ12,14-PGJ2 (15d-PGJ2).
Michiyoshi Hatanaka +6 more
doaj +1 more source
Nerve growth factor and its receptor in schizophrenia
Promising studies suggest that defects in synaptic plasticity detected in schizophrenia may be linked to neurodevelopmental and neurodegenerative abnormalities and contribute to disease-associated cognitive impairment. We aimed to clarify the role of the synaptic plasticity regulatory proteins, nerve growth factor (NGF) and its receptor (NGFR) in the ...
Zakharyan, Roksana +3 more
openaire +2 more sources
The heartbreak of depression: 'Psycho-cardiac' coupling in myocardial infarction [PDF]
Ample evidence identifies strong links between major depressive disorder (MDD) and both risk of ischemic or coronary heart disease (CHD) and resultant morbidity and mortality. The molecular mechanistic bases of these linkages are poorly defined. Systemic
Budiono, Boris P +5 more
core +1 more source
Introduction Material and methods Results ...
Susan Afshari-Stasiak +5 more
doaj +1 more source
Role of nerve growth factor and its TRKA receptor in normal ovarian and epithelial ovarian cancer angiogenesis [PDF]
In normal ovarian function a controlled angiogenesis is essential. Several growth factors are involved in this process, such as the vascular endothelial growth factor (VEGF) and nerve growth factor (NGF). The angiogenesis process in the normal ovary is a
Carmen Romero +3 more
core +1 more source
Phenotypic switching of nonpeptidergic cutaneous sensory neurons following peripheral nerve injury. [PDF]
In adult mammals, the phenotype of half of all pain-sensing (nociceptive) sensory neurons is tonically modulated by growth factors in the glial cell line-derived neurotrophic factor (GDNF) family that includes GDNF, artemin (ARTN) and neurturin (NRTN ...
Ting Wang +7 more
doaj +1 more source
Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence [PDF]
Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently ...
Berrocoso Domínguez, Esther María +4 more
core +4 more sources
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis +13 more
wiley +1 more source

