Results 81 to 90 of about 488,279 (357)

Advances in sciatic nerve regeneration: A review of contemporary techniques

Regenerative Therapy
Sciatic nerve injury, affecting the longest and thickest nerve in the human body, often leads to severe pain, weakness, and impaired motor function in the lower extremities.
Sardar Ali, Ming Sun, Muhammad Nadeem Khan, Fang Qiang   +3 more
doaj   +1 more source

Influence of the complex drug Cocarnit on the sciatic nerve in the development of diabetic polyneuropathy in rats

Current Issues in Pharmacy and Medical Sciences, 2020
Ulcers and slow wound healing are common in diabetic polyneuropathy (DP), as well as shooting or burning pain, sensitivity to touch or lack of sensitivity, low oxygenation of nerve tissue, conductivity disorders and various vascular disorders.
Nikitina Nataliia, Berehoviy Serhii, Stepanova Ludmila, Savchuk Olexiy, Kuryk Olena, Ostapchenko Ludmila, Beregova Tetyana   +6 more
doaj   +1 more source

Drosophila Neurotrophins Reveal a Common Mechanism for Nervous System Formation [PDF]

, 2008
Neurotrophic interactions occur in Drosophila, but to date, no neurotrophic factor had been found. Neurotrophins are the main vertebrate secreted signalling molecules that link nervous system structure and function: they regulate neuronal survival ...
Aberle, Alcantara, Alicia Hidalgo, Altar, Arancio, Arenas, Arendt, Armstrong, Bangfu Zhu, Barde, Barres, Beck, Belluardo, Ben Sutcliffe, Benito-Gutierrez, Bergmann, Bergner, Blum, Booth, Bossing, Bothwell, Broihier, Buj-Bello, Burke, Campos, Cash, Chao, Chen, Chevrel, Chun-Jing Gu, Coen, Collette, Collins, Conover, Crowley, Davies, Dearborn, DeLotto, Denes, Dong, Enokido, Ernfors, Ernfors, Fischbach, Freudenthal, Gangloff, Geddes, Halfon, Halfon, Hallbö, Hashimoto, Hemmrich, Henderson, Hidalgo, Hofer, Hu, Huang, Hyman, Inamori, Jaaro, Jacob, Jacobs, Janine C Fenton, Jenny A Pennack, Keishishian, Keishishian, Kenji Mizuguchi, Kirstein, Klein, Landgraf, Landgraf, Landgraf, Landgraf, Landgraf, Learte, Lee, Levi-Montalcini, Ligoxigakis, Liu, Liu, Lu, Ma, Manjon, Manuel G Forero, Martinowich, Mattson, McCabe, Means, Memet, Michael Bate, Minichiello, Mizuguchi, Mizuguchi, Morisato, Moroz, Morris, Noordermeer, Odden, Oppenheim, Oppenheim, Ormond, Parker, Peter McQuilton, Pezet, Putnam, Rogulja-Ortmann, Rose, Roux, Rubin, Sali, Scarabelli, Schmidt, Schwartz, Schweigreiter, Sendtner, Shi, Silos-Santiago, Sink, Sink, Snider, Sofroniew, Sonnenfeld, Sossin, Stadelmann, Staniszewska, Stemerdink, Tauszig, van Kesteren, Venter, Wang, Weber, Weber, White, Wright, Xiong, Zhou, Zweifel   +136 more
core   +4 more sources

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

Review: Bioengineering approach for the repair and regeneration of peripheral nerve

Bioactive Materials, 2019
Complex craniofacial surgeries of damaged tissues have several limitations, which present complications and challenges when trying to replicate facial function and structure.
Joshua Moskow, Bryan Ferrigno, Nikhil Mistry, Devina Jaiswal, Ketan Bulsara, Swetha Rudraiah, Sangamesh G. Kumbar   +6 more
doaj   +1 more source

Gender dimorphism and age of onset in malignant peripheral nerve sheath tumor preclinical models and human patients. [PDF]

, 2014
BackgroundGender-based differences in disease onset in murine models of malignant peripheral nerve sheath tumor (MPNST) and in patients with Neurofibromatosis type-1-(NF-1)-associated or spontaneous MPNST has not been well studied.MethodsForty-three ...
Dry, Sarah M, Eilber, Fritz C, Federman, Noah, Li, Yunfeng, Nakashima, Jonathan, Shurell, Elizabeth, Smith, Kathleen B, Tam, Brenna M, Tap, William D, Tran, Linh M, Wu, Hong   +10 more
core   +2 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Unaltered low nerve growth factor and high brain-derived neurotrophic factor levels in plasma from patients with fibromyalgia after a 15-week progressive resistance exercise

Journal of Rehabilitation Medicine, 2019
Background: The pathophysiology of fibromyalgia includes central and peripheral factors. Neurotrophins, such as nerve growth factor and brain-derived neurotrophic factor, are involved in peripheral and central nervous system development of pain and ...
Anna Jablochkova, Emmanuel Bäckryd, Eva Kosek, Kaisa Mannerkorpi, Malin Ernberg, Björn Gerdle, Bijar Ghafouri   +6 more
doaj   +1 more source

Exenatide promotes regeneration of injured rat sciatic nerve

Neural Regeneration Research, 2017
Damage to peripheral nerves results in partial or complete dysfunction. After peripheral nerve injuries, a full functional recovery usually cannot be achieved despite the standard surgical repairs. Neurotrophic factors and growth factors stimulate axonal
Ersin Kuyucu, Bilal Gümüs, Oytun Erbas, Fatih Oltulu, Arslan Bora   +4 more
doaj   +1 more source

Viral Vector-based Improvement of Optic Nerve Regeneration: Characterization of Individual Axons\u27 Growth Patterns and Synaptogenesis in a Visual Target [PDF]

, 2015
Lack of axon growth ability in the central nervous system poses a major barrier to achieving functional connectivity after injury. Thus, a non-transgenic regenerative approach to reinnervating targets has important implications in clinical and research ...
Blackmore, Murray G., Luo, Xueting, Salgueiro, Yadira, Yungher, Benjamin J.   +3 more
core   +1 more source