Results 71 to 80 of about 12,848,873 (295)
The nuclear events guiding successful nerve regeneration
Frontiers in Molecular Neuroscience, 2011 Peripheral nervous system (PNS) neurons survive and regenerate after nerve injury, whereas central nervous system (CNS) neurons lack the capacity to do so.
Sumiko eKiryu-Seo, Hiroshi eKiyama
doaj +1 more source
Development of a nerve stretcher for in vivo stretching of nerve fibres [PDF]
, 2019 Axons in vitro respond to mechanical stimulus and can be stretched mechanically to increase their rate of growth. This type of accelerated growth under the influence of tensile forces alone appears independent of chemical cues and growth cones.
Barton, Matthew +2 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Current Issues in Pharmacy and Medical Sciences, 2020 Ulcers and slow wound healing are common in diabetic polyneuropathy (DP), as well as shooting or burning pain, sensitivity to touch or lack of sensitivity, low oxygenation of nerve tissue, conductivity disorders and various vascular disorders.
Nikitina Nataliia +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Neural Regeneration ResearchDorsal root ganglia neurons gradually lose their axonal regeneration ability during development and aging. To explore molecules that enhance axonal regeneration, we screened growth factors with differential gene expression patterns in the dorsal root ...
Yinying Shen +4 more
doaj +1 more source
Review: Bioengineering approach for the repair and regeneration of peripheral nerve
Bioactive Materials, 2019 Complex craniofacial surgeries of damaged tissues have several limitations, which present complications and challenges when trying to replicate facial function and structure.
Joshua Moskow +6 more
doaj +1 more source
Nerve Growth Factor and Pain Mechanisms
Annual Review of Neuroscience, 2017 Nerve growth factor (NGF) antagonism is on the verge of becoming a powerful analgesic treatment for numerous conditions, including osteoarthritis and lower back pain. This review summarizes the historical research, both fundamental and clinical, that led to our current understanding of NGF biology.
Denk, Franziska +2 more
openaire +4 more sources
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Journal of Rehabilitation Medicine, 2019 Background: The pathophysiology of fibromyalgia includes central and peripheral factors. Neurotrophins, such as nerve growth factor and brain-derived neurotrophic factor, are involved in peripheral and central nervous system development of pain and ...
Anna Jablochkova +6 more
doaj +1 more source