Results 41 to 50 of about 2,724,357 (343)

Nerve injuries

open access: yesMedical Clinics of North America, 1994
Sports medicine physicians should be able to recognize and manage peripheral nerve injuries in athletes. Most often, the injury is a result of repetitive microtrauma, linking peripheral nerve injury to other musculoskeletal injuries in athletes. As with other musculoskeletal injuries, rest and a modification of the athlete's regimen often lead to ...
openaire   +2 more sources

Differential Gene Expression in Primary Cultured Sensory and Motor Nerve Fibroblasts

open access: yesFrontiers in Neuroscience, 2019
Fibroblasts (Fbs) effectively promote Schwann cells (SCs) migration, proliferation, and neurite regeneration. Whether Fbs express different motor and sensory phenotypes that regulate the cell behavior and peripheral nerve function has not been elucidated.
Qianru He   +6 more
doaj   +1 more source

Biodegradable materials for bone defect repair

open access: yesMilitary Medical Research, 2020
Compared with non-degradable materials, biodegradable biomaterials play an increasingly important role in the repairing of severe bone defects, and have attracted extensive attention from researchers.
Shuai Wei   +4 more
doaj   +1 more source

Therapeutic strategies for peripheral nerve injury: decellularized nerve conduits and Schwann cell transplantation

open access: yesNeural Regeneration Research, 2019
In recent years, the use of Schwann cell transplantation to repair peripheral nerve injury has attracted much attention. Animal-based studies show that the transplantation of Schwann cells in combination with nerve scaffolds promotes the repair of ...
Gonghai Han   +6 more
semanticscholar   +1 more source

Neuron-autonomous transcriptome changes upon ischemia/reperfusion injury

open access: yesScientific Reports, 2017
Ischemic stroke and the following reperfusion, an acute therapeutic intervention, can cause irreversible brain damages. However, the underlying pathological mechanisms are still under investigation.
Jinlong Shi   +7 more
doaj   +1 more source

Discovery of novel 2,3,4,5-tetrahydrospiro[benzo[c]azepine-1,1’-cyclohexan]-5-ol derivatives as PARP-1 inhibitors

open access: yesBMC Chemistry, 2023
As an essential marker of cancer treatment, PARP-1 inhibitors could effectively kill tumor cells through a mechanism known as synthetic lethality and are used to treat a variety of cancers.
Ling Yu   +6 more
doaj   +1 more source

Myelin sheath structure and regeneration in peripheral nerve injury repair

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Afferent and efferent nerve fibers cannot be distinguished based on the axonal diameter or the presence of the Remark bundle. The compaction of the myelin sheath involves 2 steps: 1) The distance between the 2 layers of cell membranes in the
B. Liu   +15 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Identification of hub genes related to the innate immune response activated during spinal cord injury

open access: yesFEBS Open Bio, 2022
Spinal cord injury (SCI) often leads to sensory and motor dysfunction. Two major factors that hinder spinal cord repair are local inflammation and glial scar formation after SCI, and thus appropriate immunotherapy may alleviate damage.
Jianfeng Li   +10 more
doaj   +1 more source

Surgery for nerve injury: current and future perspectives.

open access: yesJournal of Neurosurgery, 2019
In this review article, the authors offer their perspective on nerve surgery for nerve injury, with a focus on recent evolution of management and the current surgical management.
R. Midha, J. Grochmal
semanticscholar   +1 more source

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