Results 41 to 50 of about 2,702,172 (365)
BMC Chemistry, 2023 As an essential marker of cancer treatment, PARP-1 inhibitors could effectively kill tumor cells through a mechanism known as synthetic lethality and are used to treat a variety of cancers.
Ling Yu +6 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2023 Background: Intervertebral disc degeneration (IDD) is the leading cause of lower back pain, and an overall understanding of the molecular mechanisms related to IDD is still lacking. The purpose of this study was to explore gene signatures and immune cell
Tao Tang +17 more
doaj +1 more source
Unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury [PDF]
arXiv, 2022 Background: Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered as a barrier for regeneration in central nervous system (CNS), while the intrinsic mechanism of scar-forming after spinal cord injury has not been completed deciphered ...
arxiv
Neural Regeneration Research, 2019 In recent years, the use of Schwann cell transplantation to repair peripheral nerve injury has attracted much attention. Animal-based studies show that the transplantation of Schwann cells in combination with nerve scaffolds promotes the repair of ...
Gonghai Han +6 more
semanticscholar +1 more source
Lumbosacral Plexogram: An Aid to Reconstructive Nerve Possibilities in the Lower Extremity
Plastic and Reconstructive Surgery, Global OpenSummary:. The lumbosacral plexus is the network of nerves responsible for the motor and sensory function of the pelvis and lower limb. Our observation is that the anatomy of this plexus is less familiar to surgeons than that of the brachial plexus ...
Sami Ramadan, FRCS(Plast) +5 more
doaj +1 more source
Myelin sheath structure and regeneration in peripheral nerve injury repair
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Afferent and efferent nerve fibers cannot be distinguished based on the axonal diameter or the presence of the Remark bundle. The compaction of the myelin sheath involves 2 steps: 1) The distance between the 2 layers of cell membranes in the
B. Liu +15 more
semanticscholar +1 more source
Medical Clinics of North America, 1994 Sports medicine physicians should be able to recognize and manage peripheral nerve injuries in athletes. Most often, the injury is a result of repetitive microtrauma, linking peripheral nerve injury to other musculoskeletal injuries in athletes. As with other musculoskeletal injuries, rest and a modification of the athlete's regimen often lead to ...
openaire +2 more sources
Differential Gene Expression in Primary Cultured Sensory and Motor Nerve Fibroblasts
Frontiers in Neuroscience, 2019 Fibroblasts (Fbs) effectively promote Schwann cells (SCs) migration, proliferation, and neurite regeneration. Whether Fbs express different motor and sensory phenotypes that regulate the cell behavior and peripheral nerve function has not been elucidated.
Qianru He +6 more
doaj +1 more source
Biodegradable materials for bone defect repair
Military Medical Research, 2020 Compared with non-degradable materials, biodegradable biomaterials play an increasingly important role in the repairing of severe bone defects, and have attracted extensive attention from researchers.
Shuai Wei +4 more
doaj +1 more source
Update on the multimodal pathophysiological dataset of gradual cerebral ischemia in a cohort of juvenile pigs: auditory, sensory and high-frequency sensory evoked potentials [PDF]
, 2021 We expand from a spontaneous to an evoked potentials (EP) data set of brain electrical activities as electrocorticogram (ECoG) and electrothalamogram (EThG) in juvenile pig under various sedation, ischemia and recovery states. This EP data set includes three stimulation paradigms: auditory (AEP, 40 and 2000 Hz), sensory (SEP, left and right maxillary ...
arxiv +1 more source