Results 161 to 170 of about 784,496 (306)

Editorial: Peripheral Nerve Regeneration [PDF]

Frontiers in Cellular Neuroscience, 2019
Giovanna Gambarotta, Stefania Raimondo, Stefania Raimondo, Esther Udina, James B. Phillips, James B. Phillips, Kirsten Haastert-Talini, Kirsten Haastert-Talini   +7 more
openaire   +5 more sources

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

TRPC3-Driven Calcium Microdomains Instruct Peripheral Nerve Regeneration With Protective Implications for Central Neurons. [PDF]

Adv Sci (Weinh)
Lu Y, Zhao J, Xie Z, Wang Y, Wang R, Wang B, Shen C, Chen Y, Yao J, Li Z, Xu H, Chai Z, Zhang Z, Wang C, Huang R.   +14 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

An axon-intrinsic loop restricts nerve regeneration through axonal protein synthesis. [PDF]

Sci Adv
Buchanan CN, Lee J, Matoo S, Headen JA, Honoree MC, Conway M, Thompson LF, Smith TP, McKay A, Tosadori C, Dalla Costa I, Lopez De Leon M, Thames E, Perrone-Bizzozero N, Kalinski AL, Welshhans K, Vaughn LS, Twiss JL.   +17 more
europepmc   +1 more source

Extracellular matrix components in peripheral nerve repair: how to affect neural cellular response and nerve regeneration?

Peripheral nerve injury is a serious problem affecting significantly patients' life. Autografts are the "gold standard" used to repair the injury gap, however, only 50% of patients fully recover from the trauma.
Di Summa, Pietro G., De Luca, Alba C., Lacour, Stephanie P., Raffoul, Wassim   +3 more
core   +1 more source

Retina‐Inspired Bi‐Based Terahertz Photonic Neuromorphic Devices

Advanced Science, EarlyView.
Combined with effective band alignment and substrate engineering, bismuth materials are introduced to form terahertz photonic bio‐inspired devices with picosecond short‐term plasticity to enable multi‐scene visual perception. Thus obtained hardware through the terahertz optical neural network (THz‐ONN) demonstrates high recognition accuracy, providing ...
Pujing Zhang, Donggang Xie, Longyu Shi, Mengyuan Wang, Huiwen Shi, Yu Wu, Menglei Li, Guangwei She, Peijie Wang, Wensheng Shi, Cunlin Zhang, Kuijuan Jin, Guozhen Yang, Qingli Zhou, Chen Ge   +14 more
wiley   +1 more source

Fuel-maintenance coupling reprograms mitochondrial homeostasis to enable peripheral nerve regeneration. [PDF]

Mater Today Bio
Shan JK, Fang JQ, Jin XH, Xu B, Nan LP, Weng ZJ, Liu SH, Wu XH, Wu Z, Liu JJ.   +9 more
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Source-Dependent Mitochondrial Transplantation Drives Schwann Cell Bioenergetic Reprogramming and Peripheral Nerve Regeneration. [PDF]

Adv Healthc Mater
Li X, Huang Y, Cao X, Luo H, Zou Y, Aldali F, Chen S, Li Y, Zhou Q, Chen H.   +9 more
europepmc   +1 more source