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Challenges to nerve regeneration
Seminars in Surgical Oncology, 2000Peripheral nerve injuries can result from mechanical, thermal, chemical, congenital, or pathological etiologies. Failure to restore these damaged nerves can lead to the loss of muscle function, impaired sensation, and painful neuropathies. Current surgical strategies for the repair of critical nerves involve the transfer of normal donor nerve from an ...
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JAMA: The Journal of the American Medical Association, 1972
To the Editor— Rix's letter (217:480, 1971) recommending primary nerve repair in combined nerve and tendon lacerations, and the subsequent letters of Raskind et al (217:1864, 1971) and Cramer (219:1213, 1972) presented interesting discussions of the management of peripheral nerve injuries.
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To the Editor— Rix's letter (217:480, 1971) recommending primary nerve repair in combined nerve and tendon lacerations, and the subsequent letters of Raskind et al (217:1864, 1971) and Cramer (219:1213, 1972) presented interesting discussions of the management of peripheral nerve injuries.
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Nerve regeneration in diabetic rats [PDF]
Microsurgery, 1998 This study evaluated the capacity of diabetic rats to recover the ability to walk after nerve repair or nerve graft of the posterior tibial nerve at thigh level. Functional recovery of the posterior tibial nerve was evaluated by walking track analysis during regeneration in streptozotocin-induced diabetic rats.
Michael J. Im +5 more
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Diabetic Medicine, 1996
A cut peripheral nerve can be repaired by either suturing the two nerve stumps together directly or by interposing a nerve graft between the two stumps. Several factors such as the patient's age, type of injury, and proximity of the lesion will influence the functional results.
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A cut peripheral nerve can be repaired by either suturing the two nerve stumps together directly or by interposing a nerve graft between the two stumps. Several factors such as the patient's age, type of injury, and proximity of the lesion will influence the functional results.
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Spontaneous Regeneration of the Seventh Nerve
Archives of Surgery, 1960Spontaneous recovery of facial function has been reported to occur following radical parotid gland surgery, which includes resection of the facial nerve. One author 1 in a series of 28 such cases, described spontaneous recovery in over 25%. He proposed that this reinnervation occurred by the establishment of new motor pathways through the fifth cranial
Arthur G. James +3 more
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Experimental Nerve Regeneration
Otolaryngologic Clinics of North America, 1991The aim of peripheral nerve repair is to restore motor and sensory function, which requires more than just 10-0 sutures and a good microscope. The past decade has seen an explosion in the understanding of how nerves grow, and this information is being used to develop better treatments for nerve injuries.
Brian J. F. Wong, Douglas E. Mattox
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Nerve cuffs for nerve repair and regeneration
2000In the nerve regeneration field, a 'nerve cuff' is commonly understood to mean a tubular conduit that is surgically installed around the proximal and distal stumps of a severed nerve. Such tubulization cuffs are commonly used to contain the regenerating axonal sprouts and orient and guide their elongation toward the distal stump (Fig. 1, 'T-cuff').
Joaquin Andres Hoffer, Klaus Kallesøe
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Materials for Peripheral Nerve Regeneration
Macromolecular Bioscience, 2005AbstractSummary: Recent efforts in scientific research in the field of peripheral nerve regeneration have been directed towards the development of artificial nerve guides. We have studied various materials with the aim of obtaining a biocompatible and biodegradable two layer guide for nerve repair.
Gianluca Ciardelli +2 more
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Nerve Regeneration: Tissue Engineering Strategies
2006The nervous system of the adult mammal is divided into two main components: the peripheral nervous system (PNS) and central nervous system (CNS). The PNS, consisting of cranial and spinal nerves and their associated ganglia, has the intrinsic ability for repair and regeneration.
Jennifer B. Recknor +1 more
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