Results 301 to 310 of about 1,720,901 (357)

Peripheral Nerve Regeneration

JAMA: The Journal of the American Medical Association, 1972
To the Editor— Rix's letter (217:480, 1971) recommending primary nerve repair in combined nerve and tendon lacerations, and the subsequent letters of Raskind et al (217:1864, 1971) and Cramer (219:1213, 1972) presented interesting discussions of the management of peripheral nerve injuries.
openaire   +2 more sources

3D structured self-powered PVDF/PCL scaffolds for peripheral nerve regeneration

, 2020
Piezoelectric materials providing in situ electrical stimulation (ES) without applying an external chemical or physical supporting open new frontiers for future bioelectric therapies.
Yuan Cheng, Yang Xu, Yun Qian, Xuan Chen, Y. Ouyang, Weien Yuan   +5 more
semanticscholar   +1 more source

Functional Polymer‐Based Nerve Guide Conduits to Promote Peripheral Nerve Regeneration

Advanced Materials Interfaces, 2020
Bridging critical‐sized defects in peripheral nerves to achieve functional recovery is a challenge for orthopedic and hand surgeons. Inadequate regeneration of peripheral nerve axons often results in long‐term partial or total sensory and/or motor ...
Xi Zhang, W. Qu, Di Li, K. Shi, Rui Li, Yanqiu Han, E. Jin, Jianxun Ding, Xuesi Chen   +8 more
semanticscholar   +1 more source

In vitro and in vivo studies of electroactive reduced graphene oxide-modified nanofiber scaffolds for peripheral nerve regeneration.

Acta Biomaterialia, 2019
Graphene, as a promising biomaterial, has received great attention in biomedical fields due to its intriguing properties, especially the conductivity and biocompatibility.
Juan Wang, Yuan Cheng, Liang Chen, T. Zhu, Kaiqiang Ye, Chao Jia, Hongjun Wang, Meifang Zhu, C. Fan, X. Mo   +9 more
semanticscholar   +1 more source

Nanofiber arrangement regulates peripheral nerve regeneration through differential modulation of macrophage phenotypes.

Acta Biomaterialia, 2019
Topographical cues presented by aligned nanofibers have been demonstrated to stimulate peripheral nerve regeneration across long gaps, but the underlying mechanisms remain incompletely elucidated.
Yachao Jia, Weichao Yang, Kuihua Zhang, Shuo Qiu, Jia Xu, Chunyang Wang, Y. Chai   +6 more
semanticscholar   +1 more source

Exosomes from human adipose‐derived stem cells promote sciatic nerve regeneration via optimizing Schwann cell function

Journal of Cellular Physiology, 2019
Human adipose‐derived stem cells (ASCs) have a potential for the treatment of peripheral nerve injury. Recent studies demonstrated that stem cells can mediate therapeutic effect by secreting exosomes.
Jing Chen, Sen Ren, D. Duscher, Yu Kang, Yutian Liu, Cheng Wang, Meng Yuan, Guojun Guo, Hewei Xiong, P. Zhan, Yang Wang, H. Machens, Zhenbing Chen   +12 more
semanticscholar   +1 more source

Transthyretin enhances nerve regeneration

Journal of Neurochemistry, 2007
AbstractMutations in transthyretin (TTR) are associated with familial amyloid polyneuropathy, a neurodegenerative disorder characterized by TTR deposition in the PNS. The aim of this study was to unravel whether TTR has a role in nerve physiology that could account for its preferential accumulation in the PNS, when mutated. The sensorimotor performance
Carolina E, Fleming, Maria J, Saraiva, Mónica M, Sousa   +2 more
openaire   +2 more sources

Macrophages and nerve regeneration

Current Opinion in Neurobiology, 1992
Macrophages are not only phagocytic cells but also secrete a plethora of growth factors that are potentially important for regeneration. This review will examine the emerging evidence of a likely contribution by macrophages to axonal regeneration.
Perry, V. Hugh, Brown, Michael C.
openaire   +3 more sources

Stem‐cell–based therapies to enhance peripheral nerve regeneration

Muscle and Nerve, 2019
Peripheral nerve injury remains a major cause of morbidity in trauma patients. Despite advances in microsurgical techniques and improved understanding of nerve regeneration, obtaining satisfactory outcomes after peripheral nerve injury remains a ...
Carrie A. Kubiak, J. Grochmal, Theodore A Kung, P. Cederna, R. Midha, Stephen W. P. Kemp   +5 more
semanticscholar   +1 more source

Promoting optic nerve regeneration

Progress in Retinal and Eye Research, 2012
Vision is the most important sense for humans and it is irreversibly impaired by axonal damage of retinal ganglion cells (RGCs) in the optic nerve due to the lack of axonal regeneration. The failure of regeneration is partially attributable to factors located in the inhibitory environment of the forming glial scar and myelin as well as an insufficient ...
Dietmar, Fischer, Marco, Leibinger
openaire   +2 more sources