Results 311 to 320 of about 1,563,345 (405)

Neuroprotective effects of Pycnogenol on nerve regeneration and functional recovery after sciatic nerve crush injury in rodents. [PDF]

Sci Rep
Nayak BR, Acharya N, Punja D, Tomar A, Acharya AM, Punja R, Maripini N, Jayprakash RB.   +7 more
europepmc   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Advances in sciatic nerve regeneration: A review of contemporary techniques. [PDF]

Regen Ther
Ali S, Sun M, Khan MN, Qiang F.
europepmc   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source

Bioresorbable, wireless dual stimulator for peripheral nerve regeneration. [PDF]

Nat Commun
Ahn HY, Walters JB, Avila R, Oh S, Seo SG, Kim JU, Park J, Yoo S, Choi YS, Kim TY, Liu J, Yoo JY, Weissleder OR, D'Andrea D, Park C, Lee G, Cho D, Maeng WY, Yoon HJ, Wickerson G, Bouricha Y, Tian J, Chung TC, Jordan SW, Li S, Huang Y, Franz CK, Rogers JA.   +27 more
europepmc   +1 more source

Polydopamine Coupled Nt3 Derived Oriented Conductive Scaffolds with Immunomodulatory Properties Accelerates Peripheral Nerve Regeneration

Ziyuan Yang, Xiaokun Chen, Jihai Xu, Jiahua Zhou, Feng Qin, Xueyuan Li, Miao Yu, Ming Li, Yanhua Wang, Xin Wang   +9 more
openalex   +1 more source

Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder

Advanced Science, EarlyView.
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai, Mengyao Wu, Anbiao Wu, Zhaofei Jing, Zhenjie Ye, Jiayan Jin, Yaolin Zhang, Min Zhao, Genyu Liu, Xu Wang, Xiqin Yang, Jie Dong, Yunlu Xu, Jiyan Zhang   +13 more
wiley   +1 more source

Multifunctional nanoplatforms for optic nerve regeneration integrating anti-inflammatory, epigenetic, and ionic mechanisms with emerging artificial intelligence technologies. [PDF]

Cell Biol Toxicol
Wang T, Huang S, Wu J, Shi W.
europepmc   +1 more source

Reviewer #2 (Public review): Coordinated stimulation of axon regenerative and neurodegenerative transcriptional programs by ATF4 following optic nerve injury

Preethi Somasundaram, Madeline M Farley, Melissa A Rudy, Katya Sigal, Andoni I Asencor, David G Stefanoff, Malay Shah, Puneetha Goli, Jenny Heo, Shufang Wang, Nicholas M Tran, Trent A Watkins   +11 more
openalex   +1 more source