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Advanced Functional Materials, 2021
Peripheral nerve injuries are one of the most common types of traumatic damage to the nervous system. Treatment of peripheral nerve injuries aims to promote axon regrowth by imitating and improving the microenvironment for sciatic nerve regeneration.
Ying Li +9 more
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Peripheral nerve injuries are one of the most common types of traumatic damage to the nervous system. Treatment of peripheral nerve injuries aims to promote axon regrowth by imitating and improving the microenvironment for sciatic nerve regeneration.
Ying Li +9 more
semanticscholar +1 more source
Electrically Conductive Hydrogel Nerve Guidance Conduits for Peripheral Nerve Regeneration
Advanced Functional Materials, 2020Peripheral nerve injuries are serious conditions, and surgical treatment has critical limitations. Therefore, nerve guidance conduits (NGCs) are proposed as an alternative.
Junggeon Park +9 more
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Nerve regeneration and nerve repair
Neurological Research, 2008(2008). Nerve regeneration and nerve repair. Neurological Research: Vol. 30, Nerve Regeneration and Nerve Repair, pp. 997-998.
Eric L. Zager, Rajiv Midha
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Advanced Functional Materials, 2020
Peripheral nerve injury is a common clinical problem bringing heavy burden to patients, due to its high incidence and unsatisfactory treatment. Nerve guidance conduit (NGC) is a promising scaffold for peripheral nerve repair, and bioactive agents are ...
Xuan Chen +7 more
semanticscholar +1 more source
Peripheral nerve injury is a common clinical problem bringing heavy burden to patients, due to its high incidence and unsatisfactory treatment. Nerve guidance conduit (NGC) is a promising scaffold for peripheral nerve repair, and bioactive agents are ...
Xuan Chen +7 more
semanticscholar +1 more source
Neurosurgery Clinics of North America, 1991
The success of peripheral nerve regeneration is dependent on the survival of axotomized neurons, the efficacy of axonal outgrowth from those neurons, and the specificity of reinnervation of peripheral targets by those neurons. Experimental evidence indicates that following peripheral injury, primary sensory (DRG) neurons and in some cases, motoneurons ...
Bruce Tedeschi, Francis J. Liuzzi
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The success of peripheral nerve regeneration is dependent on the survival of axotomized neurons, the efficacy of axonal outgrowth from those neurons, and the specificity of reinnervation of peripheral targets by those neurons. Experimental evidence indicates that following peripheral injury, primary sensory (DRG) neurons and in some cases, motoneurons ...
Bruce Tedeschi, Francis J. Liuzzi
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Macrophages and nerve regeneration
Current Opinion in Neurobiology, 1992Macrophages are not only phagocytic cells but also secrete a plethora of growth factors that are potentially important for regeneration. This review will examine the emerging evidence of a likely contribution by macrophages to axonal regeneration.
Perry, V. Hugh, Brown, Michael C.
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Functional Polymer‐Based Nerve Guide Conduits to Promote Peripheral Nerve Regeneration
Advanced Materials Interfaces, 2020Bridging critical‐sized defects in peripheral nerves to achieve functional recovery is a challenge for orthopedic and hand surgeons. Inadequate regeneration of peripheral nerve axons often results in long‐term partial or total sensory and/or motor ...
Xi Zhang +8 more
semanticscholar +1 more source
Current Opinion in Neurology, 1995
The regeneration of nerve is a brilliant example of plasticity within the nervous system. Axonal sprouts form within a few hours of nerve injury and grow vigorously over long distances. Nonetheless, recovery from nerve injury, such as that seen after laceration of distal motor-sensory nerve, is often incomplete.
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The regeneration of nerve is a brilliant example of plasticity within the nervous system. Axonal sprouts form within a few hours of nerve injury and grow vigorously over long distances. Nonetheless, recovery from nerve injury, such as that seen after laceration of distal motor-sensory nerve, is often incomplete.
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Neuroscience Research, 1996
Peripheral nerve regeneration comprises the formation of axonal sprouts, their outgrowth as regenerating axons and the reinnervation of original targets. This review focuses on the morphological features of axonal sprouts at the node of Ranvier and their subsequent outgrowth guided by Schwann cells or by Schwann cell basal laminae.
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Peripheral nerve regeneration comprises the formation of axonal sprouts, their outgrowth as regenerating axons and the reinnervation of original targets. This review focuses on the morphological features of axonal sprouts at the node of Ranvier and their subsequent outgrowth guided by Schwann cells or by Schwann cell basal laminae.
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Challenges to nerve regeneration
Seminars in Surgical Oncology, 2000Peripheral nerve injuries can result from mechanical, thermal, chemical, congenital, or pathological etiologies. Failure to restore these damaged nerves can lead to the loss of muscle function, impaired sensation, and painful neuropathies. Current surgical strategies for the repair of critical nerves involve the transfer of normal donor nerve from an ...
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