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ACS Biomaterials Science & Engineering, 2019
Peripheral nerve regeneration and functional recovery remain a significant clinical challenge. Biomaterials that can regulate biological behavior of Schwann cell (SC) and promote neural cell differentiation are beneficial for nerve regeneration and ...
Juan Wang +7 more
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Peripheral nerve regeneration and functional recovery remain a significant clinical challenge. Biomaterials that can regulate biological behavior of Schwann cell (SC) and promote neural cell differentiation are beneficial for nerve regeneration and ...
Juan Wang +7 more
semanticscholar +1 more source
Optic nerve regeneration by peripheral nerve transplant
Neuroscience Research Supplements, 1990We studied the morphology of regenerated retinal ganglion cells and their axons in adult rodents after axotomy and autologous transplantation of the sciatic nerve. Regenerated ganglion cells, backlabeled with rhodamine dextran, were of similar size to or larger than those of intact cells in control animals.
Y, Fukuda +4 more
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Peripheral nerve regeneration through optic nerve grafts
Acta Neuropathologica, 1989Grafts of optic nerve were placed end-to-end with the proximal stumps of severed common peroneal nerves in inbred mice. It was found that fraying the proximal end of adult optic nerve grafts to disrupt the glia limitans increased their chances of being penetrated by regenerating peripheral nerve fibres.
P N, Anderson, P, Woodham, M, Turmaine
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Challenges to nerve regeneration
Seminars in Surgical Oncology, 2000Peripheral nerve injuries can result from mechanical, thermal, chemical, congenital, or pathological etiologies. Failure to restore these damaged nerves can lead to the loss of muscle function, impaired sensation, and painful neuropathies. Current surgical strategies for the repair of critical nerves involve the transfer of normal donor nerve from an ...
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Peripheral nerve regeneration using acellular nerve grafts
Journal of Biomedical Materials Research Part A, 2003AbstractLong gap peripheral nerve injuries usually require a graft to facilitate axonal regeneration into the distal nerve stump. The use of autografts is often limited because of graft availability and donor‐site morbidity. We investigated whether acellular nerve allografts would provide an appropriate channel for the promotion and induction of ...
Byung-Soo, Kim +2 more
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Cavernous nerve regeneration using acellular nerve grafts
World Journal of Urology, 2008The restoration of erectile function following complete transection of nerve tissue during surgery remains challenging. Recently, graft procedures using sural nerve grafts during radical prostatectomy have had favorable outcomes, and this has rekindled interest in the applications of neural repair in a urologic setting.
Stephen S, Connolly +5 more
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Diabetic Medicine, 1996
A cut peripheral nerve can be repaired by either suturing the two nerve stumps together directly or by interposing a nerve graft between the two stumps. Several factors such as the patient's age, type of injury, and proximity of the lesion will influence the functional results.
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A cut peripheral nerve can be repaired by either suturing the two nerve stumps together directly or by interposing a nerve graft between the two stumps. Several factors such as the patient's age, type of injury, and proximity of the lesion will influence the functional results.
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Peripheral Nerve Regeneration by Artificial Nerve Guides
2009It is more than 20 years since artificial nerve guides (or conduits) were introduced into clinical practice as a reliable alternative to autograft. They are basically cylindrical conduits inside which a regenerating nerve stump may find protection and guidance.
Merolli A., Rocchi L.
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