Results 351 to 360 of about 1,563,345 (405)

Electrospinning Multilayered Scaffolds Loaded with Melatonin and Fe3O4 Magnetic Nanoparticles for Peripheral Nerve Regeneration

Advanced Functional Materials, 2020
Peripheral nerve injury is a common clinical problem bringing heavy burden to patients, due to its high incidence and unsatisfactory treatment. Nerve guidance conduit (NGC) is a promising scaffold for peripheral nerve repair, and bioactive agents are ...
Xuan Chen, Xuemei Ge, Yun Qian, Haozheng Tang, Jialin Song, X. Qu, B. Yue, Weien Yuan   +7 more
semanticscholar   +1 more source

Peripheral Nerve Regeneration

JAMA: The Journal of the American Medical Association, 1972
To the Editor— Rix's letter (217:480, 1971) recommending primary nerve repair in combined nerve and tendon lacerations, and the subsequent letters of Raskind et al (217:1864, 1971) and Cramer (219:1213, 1972) presented interesting discussions of the management of peripheral nerve injuries.
openaire   +2 more sources

Functional Polymer‐Based Nerve Guide Conduits to Promote Peripheral Nerve Regeneration

Advanced Materials Interfaces, 2020
Bridging critical‐sized defects in peripheral nerves to achieve functional recovery is a challenge for orthopedic and hand surgeons. Inadequate regeneration of peripheral nerve axons often results in long‐term partial or total sensory and/or motor ...
Xi Zhang, W. Qu, Di Li, K. Shi, Rui Li, Yanqiu Han, E. Jin, Jianxun Ding, Xuesi Chen   +8 more
semanticscholar   +1 more source

Exosomes from human adipose‐derived stem cells promote sciatic nerve regeneration via optimizing Schwann cell function

Journal of Cellular Physiology, 2019
Human adipose‐derived stem cells (ASCs) have a potential for the treatment of peripheral nerve injury. Recent studies demonstrated that stem cells can mediate therapeutic effect by secreting exosomes.
Jing Chen, Sen Ren, D. Duscher, Yu Kang, Yutian Liu, Cheng Wang, Meng Yuan, Guojun Guo, Hewei Xiong, P. Zhan, Yang Wang, H. Machens, Zhenbing Chen   +12 more
semanticscholar   +1 more source

Transthyretin enhances nerve regeneration

Journal of Neurochemistry, 2007
AbstractMutations in transthyretin (TTR) are associated with familial amyloid polyneuropathy, a neurodegenerative disorder characterized by TTR deposition in the PNS. The aim of this study was to unravel whether TTR has a role in nerve physiology that could account for its preferential accumulation in the PNS, when mutated. The sensorimotor performance
Carolina E, Fleming, Maria J, Saraiva, Mónica M, Sousa   +2 more
openaire   +2 more sources

Macrophages and nerve regeneration

Current Opinion in Neurobiology, 1992
Macrophages are not only phagocytic cells but also secrete a plethora of growth factors that are potentially important for regeneration. This review will examine the emerging evidence of a likely contribution by macrophages to axonal regeneration.
Perry, V. Hugh, Brown, Michael C.
openaire   +3 more sources

Promoting optic nerve regeneration

Progress in Retinal and Eye Research, 2012
Vision is the most important sense for humans and it is irreversibly impaired by axonal damage of retinal ganglion cells (RGCs) in the optic nerve due to the lack of axonal regeneration. The failure of regeneration is partially attributable to factors located in the inhibitory environment of the forming glial scar and myelin as well as an insufficient ...
Dietmar, Fischer, Marco, Leibinger
openaire   +2 more sources

Stem‐cell–based therapies to enhance peripheral nerve regeneration

Muscle and Nerve, 2019
Peripheral nerve injury remains a major cause of morbidity in trauma patients. Despite advances in microsurgical techniques and improved understanding of nerve regeneration, obtaining satisfactory outcomes after peripheral nerve injury remains a ...
Carrie A. Kubiak, J. Grochmal, Theodore A Kung, P. Cederna, R. Midha, Stephen W. P. Kemp   +5 more
semanticscholar   +1 more source

Enhancement of Schwann Cells Function Using Graphene-Oxide-Modified Nanofiber Scaffolds for Peripheral Nerve Regeneration.

ACS Biomaterials Science & Engineering, 2019
Peripheral nerve regeneration and functional recovery remain a significant clinical challenge. Biomaterials that can regulate biological behavior of Schwann cell (SC) and promote neural cell differentiation are beneficial for nerve regeneration and ...
Juan Wang, Wei Zheng, Liang Chen, T. Zhu, W. Shen, C. Fan, Hongjun Wang, X. Mo   +7 more
semanticscholar   +1 more source

Optic nerve regeneration by peripheral nerve transplant

Neuroscience Research Supplements, 1990
We studied the morphology of regenerated retinal ganglion cells and their axons in adult rodents after axotomy and autologous transplantation of the sciatic nerve. Regenerated ganglion cells, backlabeled with rhodamine dextran, were of similar size to or larger than those of intact cells in control animals.
Y, Fukuda, H, Sasaki, E, Adachi, T, Inoue, K, Morigiwa   +4 more
openaire   +2 more sources