Results 21 to 30 of about 537,672 (265)
Frontiers in Physiology, 2022 Peripheral nerve injury is common, and can lead to skeletal muscle atrophy and dysfunction. However, the underlying molecular mechanisms are not fully understood. The transcription factors have been proved to play a key role in denervated muscle atrophy.
Xiaoming Yang +11 more
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Potential Therapeutic Strategies for Skeletal Muscle Atrophy
Antioxidants, 2022 The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy not only seriously reduces people’s quality of life and increases morbidity and mortality, but also causes a huge socioeconomic burden.
Li Huang +11 more
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Engineering, 2021 The molecular network features of spinal cord development that are integral to tissue engineering remain poorly understood in placental mammals, especially in terms of their relationships with vital biological processes such as regeneration.
Jian Yang +15 more
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Diabetic Muscular Atrophy: Molecular Mechanisms and Promising Therapies
Frontiers in Endocrinology, 2022 Diabetes mellitus (DM) is a typical chronic disease that can be divided into 2 types, dependent on insulin deficiency or insulin resistance. Incidences of diabetic complications gradually increase as the disease progresses.
Yuntian Shen +12 more
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Differential Gene Expression in Primary Cultured Sensory and Motor Nerve Fibroblasts
Frontiers in Neuroscience, 2019 Fibroblasts (Fbs) effectively promote Schwann cells (SCs) migration, proliferation, and neurite regeneration. Whether Fbs express different motor and sensory phenotypes that regulate the cell behavior and peripheral nerve function has not been elucidated.
Qianru He +6 more
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Biodegradable materials for bone defect repair
Military Medical Research, 2020 Compared with non-degradable materials, biodegradable biomaterials play an increasingly important role in the repairing of severe bone defects, and have attracted extensive attention from researchers.
Shuai Wei +4 more
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Neuron-autonomous transcriptome changes upon ischemia/reperfusion injury
Scientific Reports, 2017 Ischemic stroke and the following reperfusion, an acute therapeutic intervention, can cause irreversible brain damages. However, the underlying pathological mechanisms are still under investigation.
Jinlong Shi +7 more
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Materials Today Bio, 2023 Neural tissue engineering techniques typically face a significant challenge, simulating complex natural vascular systems that hinder the clinical application of tissue-engineered nerve grafts (TENGs).
Hongkui Wang +11 more
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Tissue‐Engineered Peripheral Nerve Interfaces
Advanced Functional Materials, 2017 AbstractResearch on neural interfaces has historically concentrated on development of systems for the brain; however, there is increasing interest in peripheral nerve interfaces (PNIs) that could provide benefit when peripheral nerve function is compromised, such as for amputees.
Benjamin S, Spearman +7 more
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Frontiers in Pharmacology, 2019 Skeletal muscle atrophy is a common and debilitating condition that lacks an effective therapy. Oxidative stress and inflammation are two main molecular mechanisms involved in muscle atrophy.
Ziwei Huang +8 more
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