Results 21 to 30 of about 871,938 (336)

Mechanistic Role of Reactive Oxygen Species and Therapeutic Potential of Antioxidants in Denervation- or Fasting-Induced Skeletal Muscle Atrophy

open access: yesFrontiers in Physiology, 2018
Skeletal muscle atrophy occurs under various conditions, such as disuse, denervation, fasting, aging, and various diseases. Although the underlying molecular mechanisms are still not fully understood, skeletal muscle atrophy is closely associated with ...
Jiaying Qiu   +10 more
doaj   +1 more source

Astrocyte Pannexin 1 Suppresses LPS-Induced Inflammatory Responses to Protect Neuronal SH-SY5Y Cells

open access: yesFrontiers in Cellular Neuroscience, 2021
Reactive astrogliosis is a key hallmark of inflammatory responses in the pathogenesis of brain injury, including Parkinson’s disease (PD), but its role and regulatory mechanisms are not fully understood.
Zhuo-Min Ling   +8 more
doaj   +1 more source

Quantitative analysis of cell types during growth and morphogenesis in Hydra [PDF]

open access: yes, 1973
Tissue maceration was used to determine the absolute number and the distribution of cell types in Hydra. It was shown that the total number of cells per animal as well as the distribution of cells vary depending on temperature, feeding conditions, and ...
A. Gierer   +16 more
core   +1 more source

Characterising cellular and molecular features of human peripheral nerve degeneration

open access: yesActa Neuropathologica Communications, 2020
Nerve regeneration is a key biological process in those recovering from neural trauma. From animal models it is known that the regenerative capacity of the peripheral nervous system (PNS) relies heavily on the remarkable ability of Schwann cells to ...
Matthew B. Wilcox   +6 more
doaj   +1 more source

HAT- and HDAC-Targeted Protein Acetylation in the Occurrence and Treatment of Epilepsy

open access: yesBiomedicines, 2022
Epilepsy is a common and severe chronic neurological disorder. Recently, post-translational modification (PTM) mechanisms, especially protein acetylation modifications, have been widely studied in various epilepsy models or patients.
Jie Wang   +5 more
doaj   +1 more source

Changes of Gene Expression Patterns of Muscle Pathophysiology-Related Transcription Factors During Denervated Muscle Atrophy

open access: yesFrontiers in Physiology, 2022
Peripheral nerve injury is common, and can lead to skeletal muscle atrophy and dysfunction. However, the underlying molecular mechanisms are not fully understood. The transcription factors have been proved to play a key role in denervated muscle atrophy.
Xiaoming Yang   +11 more
doaj   +1 more source

Potential Therapeutic Strategies for Skeletal Muscle Atrophy

open access: yesAntioxidants, 2022
The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy not only seriously reduces people’s quality of life and increases morbidity and mortality, but also causes a huge socioeconomic burden.
Li Huang   +11 more
doaj   +1 more source

Role of the cellular environment in interstitial stem cell proliferation in Hydra [PDF]

open access: yes, 1991
The role of the cellular environment on hydra stem cell proliferation and differentiation was investigated by introduction of interstitial cells into host tissue of defined cellular composition.
Bosch, Thomas C. G.   +3 more
core   +1 more source

Developmental Temporal Patterns and Molecular Network Features in the Transcriptome of Rat Spinal Cord

open access: yesEngineering, 2021
The molecular network features of spinal cord development that are integral to tissue engineering remain poorly understood in placental mammals, especially in terms of their relationships with vital biological processes such as regeneration.
Jian Yang   +15 more
doaj   +1 more source

Nerve commitment in Hydra. I. Role of morphogenetic signals [PDF]

open access: yes, 1981
The kinetics of nerve commitment during head regeneration in Hydra were investigated using a newly developed assay for committed cells. Committed nerve precursors were assayed by their ability to continue nerve differentiation following explanation of ...
Berking   +25 more
core   +1 more source

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