Results 21 to 30 of about 871,938 (336)
Skeletal muscle atrophy occurs under various conditions, such as disuse, denervation, fasting, aging, and various diseases. Although the underlying molecular mechanisms are still not fully understood, skeletal muscle atrophy is closely associated with ...
Jiaying Qiu +10 more
doaj +1 more source
Astrocyte Pannexin 1 Suppresses LPS-Induced Inflammatory Responses to Protect Neuronal SH-SY5Y Cells
Reactive astrogliosis is a key hallmark of inflammatory responses in the pathogenesis of brain injury, including Parkinson’s disease (PD), but its role and regulatory mechanisms are not fully understood.
Zhuo-Min Ling +8 more
doaj +1 more source
Quantitative analysis of cell types during growth and morphogenesis in Hydra [PDF]
Tissue maceration was used to determine the absolute number and the distribution of cell types in Hydra. It was shown that the total number of cells per animal as well as the distribution of cells vary depending on temperature, feeding conditions, and ...
A. Gierer +16 more
core +1 more source
Characterising cellular and molecular features of human peripheral nerve degeneration
Nerve regeneration is a key biological process in those recovering from neural trauma. From animal models it is known that the regenerative capacity of the peripheral nervous system (PNS) relies heavily on the remarkable ability of Schwann cells to ...
Matthew B. Wilcox +6 more
doaj +1 more source
HAT- and HDAC-Targeted Protein Acetylation in the Occurrence and Treatment of Epilepsy
Epilepsy is a common and severe chronic neurological disorder. Recently, post-translational modification (PTM) mechanisms, especially protein acetylation modifications, have been widely studied in various epilepsy models or patients.
Jie Wang +5 more
doaj +1 more source
Peripheral nerve injury is common, and can lead to skeletal muscle atrophy and dysfunction. However, the underlying molecular mechanisms are not fully understood. The transcription factors have been proved to play a key role in denervated muscle atrophy.
Xiaoming Yang +11 more
doaj +1 more source
Potential Therapeutic Strategies for Skeletal Muscle Atrophy
The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy not only seriously reduces people’s quality of life and increases morbidity and mortality, but also causes a huge socioeconomic burden.
Li Huang +11 more
doaj +1 more source
Role of the cellular environment in interstitial stem cell proliferation in Hydra [PDF]
The role of the cellular environment on hydra stem cell proliferation and differentiation was investigated by introduction of interstitial cells into host tissue of defined cellular composition.
Bosch, Thomas C. G. +3 more
core +1 more source
The molecular network features of spinal cord development that are integral to tissue engineering remain poorly understood in placental mammals, especially in terms of their relationships with vital biological processes such as regeneration.
Jian Yang +15 more
doaj +1 more source
Nerve commitment in Hydra. I. Role of morphogenetic signals [PDF]
The kinetics of nerve commitment during head regeneration in Hydra were investigated using a newly developed assay for committed cells. Committed nerve precursors were assayed by their ability to continue nerve differentiation following explanation of ...
Berking +25 more
core +1 more source

