Diabetic Muscular Atrophy: Molecular Mechanisms and Promising Therapies
Frontiers in Endocrinology, 2022 Diabetes mellitus (DM) is a typical chronic disease that can be divided into 2 types, dependent on insulin deficiency or insulin resistance. Incidences of diabetic complications gradually increase as the disease progresses.
Yuntian Shen +12 more
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Differential Gene Expression in Primary Cultured Sensory and Motor Nerve Fibroblasts
Frontiers in Neuroscience, 2019 Fibroblasts (Fbs) effectively promote Schwann cells (SCs) migration, proliferation, and neurite regeneration. Whether Fbs express different motor and sensory phenotypes that regulate the cell behavior and peripheral nerve function has not been elucidated.
Qianru He +6 more
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Nerve tissue engineering using blends of Polyhydroxyalkanoates [PDF]
, 2017 PHAs are a family of linear polyesters consisting of 3, 4, 5 and 6-hydroxyacids, synthesized by a variety of bacterial species. They can be produced from renewable carbon sources, they are biodegradable, biocompatible and exhibit thermoplastic and ...
Lizarraga Valderrama, L.
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Neuron-autonomous transcriptome changes upon ischemia/reperfusion injury
Scientific Reports, 2017 Ischemic stroke and the following reperfusion, an acute therapeutic intervention, can cause irreversible brain damages. However, the underlying pathological mechanisms are still under investigation.
Jinlong Shi +7 more
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Biodegradable materials for bone defect repair
Military Medical Research, 2020 Compared with non-degradable materials, biodegradable biomaterials play an increasingly important role in the repairing of severe bone defects, and have attracted extensive attention from researchers.
Shuai Wei +4 more
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Nerve endings with structural characteristics of mechanoreceptors in the human scleral spur [PDF]
, 1994 PURPOSE: The innervation of the scleral spur region was investigated to learn whether mechano-receptors are present in this region. METHODS: Serial tangential sections and whole-mount preparations of the scleral spur region of 18 human eyes of ...
Stefani, F. H. +3 more
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The properties of nerve cell precursors in hydra [PDF]
, 1986 Two signals, the head activator and an injury stimulus, control differentiation of nerve cells from uncommitted stem cells in hydra [Th. Holstein, H. C. Schaller, and C. N. David, (1986) Dev. Biol. 115, 9–17].
Holstein, Thomas W., David, Charles N.
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Near-Infrared Spectral Similarity between Ex Vivo Porcine and In Vivo Human Tissue
Life, 2023 Background: In vivo diffuse reflectance spectroscopy provides additional contrast in discriminating nerves embedded in adipose tissue during surgery. However, large datasets are required to achieve clinically acceptable classification levels.
Eva de Vries +6 more
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Putative intermediates in the nerve cell differentiation pathway in hydra have properties of multipotent stem cells [PDF]
, 1990 We have investigated the properties of nerve cell precursors in hydra by analyzing the differentiation and proliferation capacity of interstitial cells in the peduncle of Hydra oligactis, which is a region of active nerve cell differentiation.
Charles +4 more
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Willin, an upstream component of the Hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblasts [PDF]
, 2013 Willin/FRMD6 was first identified in the rat sciatic nerve, which is composed of neurons, Schwann cells, and fibroblasts. Willin is an upstream component of the Hippo signaling pathway, which results in the inactivation of the transcriptional coactivator
Tilston-Lünel, A.M. +45 more
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