Results 31 to 40 of about 869,390 (314)

Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]

open access: yes, 2018
BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila   +6 more
core   +2 more sources

Differential Gene Expression in Primary Cultured Sensory and Motor Nerve Fibroblasts

open access: yesFrontiers in Neuroscience, 2019
Fibroblasts (Fbs) effectively promote Schwann cells (SCs) migration, proliferation, and neurite regeneration. Whether Fbs express different motor and sensory phenotypes that regulate the cell behavior and peripheral nerve function has not been elucidated.
Qianru He   +6 more
doaj   +1 more source

Biodegradable materials for bone defect repair

open access: yesMilitary Medical Research, 2020
Compared with non-degradable materials, biodegradable biomaterials play an increasingly important role in the repairing of severe bone defects, and have attracted extensive attention from researchers.
Shuai Wei   +4 more
doaj   +1 more source

Neuron-autonomous transcriptome changes upon ischemia/reperfusion injury

open access: yesScientific Reports, 2017
Ischemic stroke and the following reperfusion, an acute therapeutic intervention, can cause irreversible brain damages. However, the underlying pathological mechanisms are still under investigation.
Jinlong Shi   +7 more
doaj   +1 more source

Tissue‐Engineered Peripheral Nerve Interfaces

open access: yesAdvanced Functional Materials, 2017
AbstractResearch on neural interfaces has historically concentrated on development of systems for the brain; however, there is increasing interest in peripheral nerve interfaces (PNIs) that could provide benefit when peripheral nerve function is compromised, such as for amputees.
Benjamin S, Spearman   +7 more
openaire   +3 more sources

Skeletal Muscle Atrophy Was Alleviated by Salidroside Through Suppressing Oxidative Stress and Inflammation During Denervation

open access: yesFrontiers in Pharmacology, 2019
Skeletal muscle atrophy is a common and debilitating condition that lacks an effective therapy. Oxidative stress and inflammation are two main molecular mechanisms involved in muscle atrophy.
Ziwei Huang   +8 more
doaj   +1 more source

Near-Infrared Spectral Similarity between Ex Vivo Porcine and In Vivo Human Tissue

open access: yesLife, 2023
Background: In vivo diffuse reflectance spectroscopy provides additional contrast in discriminating nerves embedded in adipose tissue during surgery. However, large datasets are required to achieve clinically acceptable classification levels.
Eva de Vries   +6 more
doaj   +1 more source

Recent advances in NIR-II fluorescence based theranostic approaches for glioma

open access: yesFrontiers in Chemistry, 2022
Gliomas are among the most common malignant tumors in the central nervous system and lead to poor life expectancy. However, the effective treatment of gliomas remains a considerable challenge.
Jiaying Li   +3 more
doaj   +1 more source

Neural tissue-engineered prevascularization in vivo enhances peripheral neuroregeneration via rapid vascular inosculation

open access: yesMaterials Today Bio, 2023
Neural tissue engineering techniques typically face a significant challenge, simulating complex natural vascular systems that hinder the clinical application of tissue-engineered nerve grafts (TENGs).
Hongkui Wang   +11 more
doaj   +1 more source

Immunomodulation stimulates the innervation of engineered tooth organ [PDF]

open access: yes, 2014
The sensory innervation of the dental mesenchyme is essential for tooth function and protection. Sensory innervation of the dental pulp is mediated by axons originating from the trigeminal ganglia and is strictly regulated in time. Teeth can develop from
Bécavin, Thibault   +5 more
core   +5 more sources

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