Results 21 to 30 of about 869,390 (314)

Characterising cellular and molecular features of human peripheral nerve degeneration

open access: yesActa Neuropathologica Communications, 2020
Nerve regeneration is a key biological process in those recovering from neural trauma. From animal models it is known that the regenerative capacity of the peripheral nervous system (PNS) relies heavily on the remarkable ability of Schwann cells to ...
Matthew B. Wilcox   +6 more
doaj   +1 more source

HAT- and HDAC-Targeted Protein Acetylation in the Occurrence and Treatment of Epilepsy

open access: yesBiomedicines, 2022
Epilepsy is a common and severe chronic neurological disorder. Recently, post-translational modification (PTM) mechanisms, especially protein acetylation modifications, have been widely studied in various epilepsy models or patients.
Jie Wang   +5 more
doaj   +1 more source

Nerve cell differentiation in hydra requires two signals [PDF]

open access: yes, 1986
Endogenous signals controlling nerve cell commitment in hydra were investigated using an assay for committed nerve precursors. Extracts of hydra tissue were prepared and tested for their ability to induce nerve cell commitment.
Berking   +28 more
core   +1 more source

Changes of Gene Expression Patterns of Muscle Pathophysiology-Related Transcription Factors During Denervated Muscle Atrophy

open access: yesFrontiers in Physiology, 2022
Peripheral nerve injury is common, and can lead to skeletal muscle atrophy and dysfunction. However, the underlying molecular mechanisms are not fully understood. The transcription factors have been proved to play a key role in denervated muscle atrophy.
Xiaoming Yang   +11 more
doaj   +1 more source

Histological markers in nasal mucosa of patients with Alzheimer's disease [PDF]

open access: yes, 1998
Neuropathological changes such as dystrophic neurites and the presence of abnormal tau protein in the olfactory system, including primary sensory cells and nerve fibres have previously been demonstrated in nasal mucosa tissue of patients with Alzheimer's
Golombowski, Sidonie   +7 more
core   +1 more source

Potential Therapeutic Strategies for Skeletal Muscle Atrophy

open access: yesAntioxidants, 2022
The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy not only seriously reduces people’s quality of life and increases morbidity and mortality, but also causes a huge socioeconomic burden.
Li Huang   +11 more
doaj   +1 more source

Developmental Temporal Patterns and Molecular Network Features in the Transcriptome of Rat Spinal Cord

open access: yesEngineering, 2021
The molecular network features of spinal cord development that are integral to tissue engineering remain poorly understood in placental mammals, especially in terms of their relationships with vital biological processes such as regeneration.
Jian Yang   +15 more
doaj   +1 more source

Activity of Cyclic AMP Phosphodiesterases and Adenylyl Cyclase in Peripheral Nerve after Crush and Permanent Transection Injuries [PDF]

open access: yes, 1998
Recent studies demonstrate that cAMP levels are tightly controlled during demyelination and remyelination in Schwann cells as cAMP decreases to 8–10% of normal following both sciatic nerve crush or permanent transection injury and only begins to increase
Poduslo, Joseph F.   +1 more
core   +1 more source

Transplantation stimulates interstitial cell migration in hydra [PDF]

open access: yes, 1990
Migration of interstitial cells and nerve cell precursors was analyzed in Hydra magnipapillata and Hydra vulgaris (formerly Hydra attenuata). Axial grafts were made between [3H]thymidine-labeled donor and unlabeled host tissue. Migration of labeled cells
Bosch   +10 more
core   +1 more source

Diabetic Muscular Atrophy: Molecular Mechanisms and Promising Therapies

open access: yesFrontiers in Endocrinology, 2022
Diabetes mellitus (DM) is a typical chronic disease that can be divided into 2 types, dependent on insulin deficiency or insulin resistance. Incidences of diabetic complications gradually increase as the disease progresses.
Yuntian Shen   +12 more
doaj   +1 more source

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