Results 151 to 160 of about 380,937 (310)

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

Advanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang, Myungji Kim, Hwanyong Choi, Jinseon Park, Minji Kim, Donghwan Kim, Bo Ram Lee, Jinah Jang   +7 more
wiley   +1 more source

CXCL12 Promotes Peripheral Nerve Injury Repair by Inhibiting the Ferroptosis-Inflammation Axis via the ERK/Nrf2 Pathway. [PDF]

Inflammation
Yuan Y, Jiang Y, Du S, Yuan G, Yang Z, Wang P.   +5 more
europepmc   +1 more source

Understanding the Effects of Conductive Polymer Electrode Coating on Recorded Neural Signals

Advanced Healthcare Materials, EarlyView.
Conductive polymer coatings are widely explored to improve the quality of signals recorded with chronically implanted neural electrodes, offering enhanced biocompatibility along with reduced electrode impedance. Combining computational modelling and data from PEDOT:PTS coated and PtIr electrodes in rats, we show that improvements in signal quality with
Karthik Sridhar, Judith Evers, Alexandre Trotier, Manus Biggs, Madeleine M. Lowery   +4 more
wiley   +1 more source

Bilateral optic neuritis and multiple nerve sheath tumors in a patient with genetically characterized Ehlers-Danlos syndrome: A rare co-occurrence. [PDF]

Radiol Case Rep
Larios A BR, Mendoza Blandón MS, Barahona Vargas S, Romero Ríos CK.   +3 more
europepmc   +1 more source

SALMFamide salmagundi: The biology of a neuropeptide family in echinoderms [PDF]

, 2014
Ajayi, Aloyz, Beer, Bremaeker, Burke, Burns, Byrne, Byrne, Cisternas, Clarke, Cobb, Cobb, Conzelmann, Conzelmann, De Bremaeker, De Bremaeker, De Bremaeker, Du, Dupont, Díaz-Miranda, Díaz-Miranda, Díaz-Miranda, Elphick, Elphick, Elphick, Elphick, Elphick, Elphick, Elphick, Elphick, Elphick, Fujisawa, García-Arrarás, García-Arrarás, Ghyoot, Heinzeller, Heinzeller, Hewes, Hirokawa, Hoekstra, Jekely, Jorgensen, Lange, Mallefet, Maurice R. Elphick, Melarange, Melarange, Mirabeau, Mita, Mita, Moore, Moss, Nakano, Newman, Newman, Ohtani, Otara, Pentreath, Pisani, Price, Price, Primeaux, Rowe, Rowe, Semmens, Sodergren, Thorndyke, Tsutsui, Ubuka, Wegener, Yun, Yun   +71 more
core   +1 more source

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

33 | Identification of mtorc1-dependent muscle-specific factors involved in nmj maintenance

European Journal of Translational Myology
Neuromuscular junction (NMJ) dysfunction contributes to muscle wasting in numerous neuromuscular diseases such as ALS and age-related sarcopenia. Interestingly, in the last few years it has become clear that skeletal muscle fibers play a critical role to
Interuniversity Institute of Myology
doaj  

Peptide-Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries. [PDF]

Adv Sci (Weinh)
Zhao Z, Liu J, Li J, Li D, Ding J, Liu B.   +5 more
europepmc   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source