Results 161 to 170 of about 3,683,030 (295)

All‐Amyloid Functional Coacervates

Advanced Materials, EarlyView.
This study introduces an all‐amyloid interfacial complex coacervate technique that employs charge‐mediated or functionalization‐assisted complexation of oppositely charged food protein‐derived amyloid nanofibrils to engineer functional soft constructs across multiple length scales.
Seyyed Alireza Hashemi, Mohammad Peydayesh, Laura Baraldi, Mohammad Arjmand, Raffaele Mezzenga   +4 more
wiley   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio-Interactive Materials. [PDF]

Adv Sci (Weinh)
Fan Q, Cao F, Mao J, Yin P, Zhang L, Wang J, Tang P.   +6 more
europepmc   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

A deep-learning framework reveals whole-body perturbations at cell level. [PDF]

Nature
Kaltenecker D, Horvath I, Al-Maskari R, Chen Y, Kolabas ZI, Hoeher L, Todorov M, Minde DP, Kapoor S, Turhan SG, Kuemmerle LB, Steinke H, Wohlgemuth T, Ali M, Kofler F, Morigny P, Geppert J, Jeridi D, Wittmann B, Luo J, Shit S, Cigankova C, Kolenic VM, Gür N, Aydeniz E, Yücecan A, Ertürk M, Simons LHA, Pan C, Piraud M, Rueckert D, Rohm M, Hellal F, Elsner M, Bhatia HS, Bechmann I, Menze BH, Herzig S, Paetzold JC, Diaz MB, Ertürk A.   +40 more
europepmc   +1 more source

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Schwann cell derived extracellular vesicles are multifunctional nanotherapeutic mediators for diabetic oral mucosal wound healing. [PDF]

Discov Nano
Xu Z, Qi H, Zhang X, Qu F, Wu Y, Xu C.
europepmc   +1 more source

Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated Excitability

Advanced Materials, EarlyView.
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn, Min‐seop Kim, Ju‐Hee Kim, Seok‐Hyeon Kang, Dain Lee, Hui‐Wen Liu, Seung‐cheol Shin, Kyuhwan Na, Yesl Jun, Oak‐Kee Hong, Ji Hun Yang, Jin‐A Kim, Hwanseok Jang, Hong Nam Kim, Roger D. Kamm, Ji‐Hoon Kim, Jang‐Won Son, Seok Chung   +17 more
wiley   +1 more source

Peripheral Nerve Injury and Denervation-Induced Sarcopenia with a Focus on Pharmacological Dual-Target Strategies. [PDF]

Biomol Ther (Seoul)
Yun C, Won JH, Lee SY, Kim TH, Kim GH, Lee JI.   +5 more
europepmc   +1 more source

Morphological Characterization of Spherulites in Silk‐Polycaprolactone Mixtures: Implications for Textured Materials

Advanced Materials Interfaces, EarlyView.
Blending silk fibroin with polycaprolactone alters crystalline organization and surface morphology. Low fibroin levels promote ring‐banded spherulites, while higher contents generate porous, pit‐like textures, though overall crystallinity remains unchanged. Solvent evaporation further modulates surface patterns.
Karolína Kocourková, David Jaška, Miroslav Mrlík, Markéta Kadlečková, Filip Mikulka, Roman Čermák, Lucie Kubíčková, Marek Joukal, Petr Smolka, Martin Humenik, Antonín Minařík   +10 more
wiley   +1 more source