Systematic genomic Mendelian randomization profiling of early molecular markers of optic atrophy. [PDF]
Yang JZ +6 more
europepmc +1 more source
Temporal Neuromuscular Adaptations and Proteomic Signatures Following Botulinum Neurotoxin A Injection in Spastic Hemiplegia Rats. [PDF]
Zhong M +10 more
europepmc +1 more source
Using an integrated omics approach to uncover the mechanisms underlying chemotherapy-induced peripheral neuropathy (CIPN). [PDF]
Piga I +5 more
europepmc +1 more source
Hypoxia-preconditioned mitochondrial transplantation multidirectionally modulates Schwann cell functions to repair peripheral nerve injury in rats. [PDF]
Dong J +12 more
europepmc +1 more source
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Whole intact tissue electrophoresis of nerve proteins
Journal of Neuroscience Methods, 1993We describe a rapid and simple method for analyzing proteins along the length of a nerve tissue using sodium dodecylsulfate-polyacrylamide gel electrophoresis (SDS-PAGE). A long length of nerve tissue is placed on a slab gel, layered with SDS-buffer, and electrophoresed.
George Bittner
exaly +3 more sources
Changes of cytoskeletal proteins in nerve tissues and serum of rats treated with 2,5-hexanedione
Toxicology, 2008To investigate the mechanisms and biomarker of the neuropathy induced by 2,5-hexanedione (HD), male Wistar rats were administrated HD at dosage of 200 or 400mg/kg for 8 weeks (five-times per week). All rats were sacrificed after 8 weeks of treatment and the cerebrum cortex (CC), spinal cord (SC) and sciatic nerves (SN) were dissected, homogenized and ...
Qing-Shan, Wang +4 more
openaire +2 more sources
Human PRUNE is thought to enhance the metastasis of tumor cells. We found that a hypothetical paralog of PRUNE, PRUNE2, binds to 8-oxo-GTP, an oxidized form of GTP. Hypothetical PRUNE2 gene consists of C9orf65 and BMCC1/BNIPXL, both of which are malignant tumor-associated genes.
Eiji, Iwama +7 more
openaire +2 more sources
Aim: To determine the effect of laser irradiation of different spectrum on the expression of neuronal proteins (GFAP, S100, NSE and NF-L) in the sciatic nerve during its regeneration after crossing and surgical suturing. Materials and methods: The experiment was performed on 60 laboratory rats of the Wistar line (200-250 g) with crossing of the left ...
Zinovii M, Yashchyshyn +6 more
openaire +2 more sources
Allyl chloride (AC) is widely used in industries as raw material and has been reported to produce occupational peripheral neuropathies in man chronically exposure to it. Although many studies have been done addressing to it, the mechanisms still remain unclear.
Qing-Shan, Wang +4 more
openaire +2 more sources
[Autoantibodies against nerve tissue proteins long after cranio-cerebral injury].
Voprosy meditsinskoi khimii, 199720 samples of serum of patients with remote consequences of brain trauma were tested to detect autoantibodies (a-AB) against brain proteins S-100 and NKP. Essential pathology was not found out by standard solid-phase immunoassay. The original method was used to detect a-AB to the whole complex of antigen determinants. Using this method the elevation of
S G, Morozov +4 more
openaire +2 more sources

