Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Despite the many benefits of mesenchymal stem cell (MSC) transplantation for tissue regeneration, there are some limitations to using them, including the high costs, applying invasive procedures, the possibility of transplant rejection, and
Mitra Ghasemi +8 more
doaj +1 more source
Adipose-derived stem cells stimulate regeneration of peripheral nerves: BDNF secreted by these cells promotes nerve healing and axon growth de novo. [PDF]
PLoS ONE, 2011 Transplantation of adipose-derived mesenchymal stem cells (ASCs) induces tissue regeneration by accelerating the growth of blood vessels and nerve. However, mechanisms by which they accelerate the growth of nerve fibers are only partially understood.
Tatiana Lopatina +8 more
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Nerve cell differentiation in hydra requires two signals [PDF]
, 1986 Endogenous signals controlling nerve cell commitment in hydra were investigated using an assay for committed nerve precursors. Extracts of hydra tissue were prepared and tested for their ability to induce nerve cell commitment.
Schaller, Chica H. +2 more
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Peripheral nerve tissue engineering
, 2021 Peripheral nerve injury is a frequent clinical problem and causes loss of motor and sensory functions for patients. Though some inherent regeneration capacity exists, this is often very limited in the cases of nerve tissue gaps.
Vijay Kumar Kuna +3 more
core +1 more source
Quantitative mass spectrometry analysis of the injured proximal and distal human digital nerve ends
Frontiers in Molecular NeuroscienceIntroductionProteomic analysis of injured human peripheral nerves, particularly focusing on events occurring in the proximal and distal nerve ends, remains relatively underexplored.
Drifa Frostadottir +7 more
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Bio-Protocol, 2015 After stroke and brain contusion, serum proteins extravasate into nerve tissue through disrupted blood-brain barrier (BBB). Because extravasations of serum proteins result in vasogenic brain edema, serum albumin level in the brain is an indicator of BBB
Shotaro Michinaga, Yutaka Koyama
doaj +1 more source
Activation of neurotrophins in lumbar dorsal root probably contributes to neuropathic pain after spinal nerve ligation [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Objective(s): Neurotrophins (NTs) exert various effects on neuronal system. Growing evidence indicates that NTs are involved in the pathophysiology of neuropathic pain.
Abdolreza Kazemi +3 more
doaj +1 more source
Relationship between the tissue-specificity of mouse gene expression and the evolutionary origin and function of the proteins. [PDF]
, 2005 BACKGROUND: The combination of complete genome sequence information with expression data enables us to characterize the relationship between a protein's evolutionary origin or functional category and its expression pattern.
Thornton, Janet M +6 more
core +6 more sources
Molecular Pain, 2008 Neuropathic pain may arise following peripheral nerve injury though the molecular mechanisms associated with this are unclear. We used proteomic profiling to examine changes in protein expression associated with the formation of hyper-excitable neuromas ...
Timms John F +6 more
doaj +1 more source
Neural Regeneration Research, 2019 Wallerian degeneration and nerve regeneration after injury are complex processes involving many genes, proteins and cytokines. After different peripheral nerve injuries the regeneration rate can differ.
Yao-Fa Lin +4 more
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