Results 21 to 30 of about 233,776 (264)

Induction of ectopic retina-like tissue by transgenic expression of neurogenin.

PLoS ONE, 2015
Degeneration of retinal neurons is an underlying cause of several major types of blinding diseases, and effective therapies remain to be developed. The suppositive strategy of repopulating a degenerative retina with new cells generated onsite faces ...
Run-Tao Yan, Li He, Wenjie Zhan, Shu-Zhen Wang   +3 more
doaj   +1 more source

Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Despite the many benefits of mesenchymal stem cell (MSC) transplantation for tissue regeneration, there are some limitations to using them, including the high costs, applying invasive procedures, the possibility of transplant rejection, and
Mitra Ghasemi, Athar Talebi, Ali Ghanbari, Parisa Hayat, Behpour Yousefi, Moslem Mohammadi, Mahmood Abedinzade, Nooshin Ahmadirad, Sam Zarbakhsh   +8 more
doaj   +1 more source

Adipose-derived stem cells stimulate regeneration of peripheral nerves: BDNF secreted by these cells promotes nerve healing and axon growth de novo. [PDF]

PLoS ONE, 2011
Transplantation of adipose-derived mesenchymal stem cells (ASCs) induces tissue regeneration by accelerating the growth of blood vessels and nerve. However, mechanisms by which they accelerate the growth of nerve fibers are only partially understood.
Tatiana Lopatina, Natalia Kalinina, Maxim Karagyaur, Dmitry Stambolsky, Kseniya Rubina, Alexander Revischin, Galina Pavlova, Yelena Parfyonova, Vsevolod Tkachuk   +8 more
doaj   +1 more source

Nerve tissue growth factors as markers of evaluation of neuro-genesis processes in traumatic spinal cord disease [PDF]

Саратовский научно-медицинский журнал, 2014
Objective: immunological differentiation effects regeneration of nerve tissue in the acute and early periods of traumatic spinal cord disease on the basis of assessment of the dynamics of content neurospecific proteins in serum affected.
Uljanov V.Yu., Norkin I.A., Drozdova G.A., Konjuchenko E.A.   +3 more
doaj  

ELISA Detection of Endogenous Serum Albumin in the Mouse Brain: A Measure of Extravasation Following Brain Injury

Bio-Protocol, 2015
After stroke and brain contusion, serum proteins extravasate into nerve tissue through disrupted blood-brain barrier (BBB). Because extravasations of serum proteins result in vasogenic brain edema, serum albumin level in the brain is an indicator of BBB
Shotaro Michinaga, Yutaka Koyama
doaj   +1 more source

Activation of neurotrophins in lumbar dorsal root probably contributes to neuropathic pain after spinal nerve ligation [PDF]

Iranian Journal of Basic Medical Sciences, 2017
Objective(s): Neurotrophins (NTs) exert various effects on neuronal system. Growing evidence indicates that NTs are involved in the pathophysiology of neuropathic pain.
Abdolreza Kazemi, Masoud Rahmati, Rasoul Eslami, Vahid Sheibani   +3 more
doaj   +1 more source

Quantitative mass spectrometry analysis of the injured proximal and distal human digital nerve ends

Frontiers in Molecular Neuroscience
IntroductionProteomic analysis of injured human peripheral nerves, particularly focusing on events occurring in the proximal and distal nerve ends, remains relatively underexplored.
Drifa Frostadottir, Drifa Frostadottir, Charlotte Welinder, Raquel Perez, Raquel Perez, Lars B. Dahlin, Lars B. Dahlin, Lars B. Dahlin   +7 more
doaj   +1 more source

Proteomic profiling of neuromas reveals alterations in protein composition and local protein synthesis in hyper-excitable nerves

Molecular Pain, 2008
Neuropathic pain may arise following peripheral nerve injury though the molecular mechanisms associated with this are unclear. We used proteomic profiling to examine changes in protein expression associated with the formation of hyper-excitable neuromas ...
Timms John F, Cramer Rainer, Okuse Kenji, Roza Carolina, Cendan Cruz-Miguel, Huang Hong-Lei, Wood John N   +6 more
doaj   +1 more source

Peripheral Nerve Regeneration–Adipose-Tissue-Derived Stem Cells Differentiated by a Three-Step Protocol Promote Neurite Elongation via NGF Secretion

Cells, 2022
The lack of supportive Schwann cells in segmental nerve lesions seems to be one cornerstone for the problem of insufficient nerve regeneration. Lately, adipose-tissue-derived stem cells (ASCs) differentiated towards SC (Schwann cell)-like cells seem to ...
Silvan Klein, Andreas Siegmund, Andreas Eigenberger, Valerie Hartmann, Felix Langewost, Nicolas Hammer, Alexandra Anker, Konstantin Klein, Christian Morsczeck, Lukas Prantl, Oliver Felthaus   +10 more
doaj   +1 more source

Differential gene and protein expression between rat tibial nerve and common peroneal nerve during Wallerian degeneration

Neural Regeneration Research, 2019
Wallerian degeneration and nerve regeneration after injury are complex processes involving many genes, proteins and cytokines. After different peripheral nerve injuries the regeneration rate can differ.
Yao-Fa Lin, Zheng Xie, Jun Zhou, Gang Yin, Hao-Dong Lin   +4 more
doaj   +1 more source