Results 61 to 70 of about 1,158,334 (373)

Neurofilaments and Neurofilament Proteins in Health and Disease.

Cold Spring Harbor Perspectives in Biology, 2017
SUMMARYNeurofilaments (NFs) are unique among tissue-specific classes of intermediate filaments (IFs) in being heteropolymers composed of four subunits (NF-L [neurofilament light]; NF-M [neurofilament middle]; NF-H [neurofilament heavy]; and α-internexin ...
A. Yuan, M. Rao, Veeranna, R. Nixon
semanticscholar   +1 more source

Histological markers in nasal mucosa of patients with Alzheimer's disease [PDF]

, 1998
Neuropathological changes such as dystrophic neurites and the presence of abnormal tau protein in the olfactory system, including primary sensory cells and nerve fibres have previously been demonstrated in nasal mucosa tissue of patients with Alzheimer's
Golombowski, Sidonie, Hock, Christoph, Mandelkow, Eva-Maria, Müller-Spahn, Franz, Peschel, Oliver, Probst, Alphonse, Riederer, Andreas, Unger, Jürgen   +7 more
core   +1 more source

Time course analysis of sensory axon regeneration in vivo by directly tracing regenerating axons

Neural Regeneration Research, 2020
Most current studies quantify axon regeneration by immunostaining regeneration-associated proteins, representing indirect measurement of axon lengths from both sensory neurons in the dorsal root ganglia and motor neurons in the spinal cord.
Yan Gao, Yi-Wen Hu, Run-Shan Duan, Shu-Guang Yang, Feng-Quan Zhou, Rui-Ying Wang   +5 more
doaj   +1 more source

Advances in stem cell therapy for sensory nerve injury

Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Sensory nerves belong to the afferent nerve part of the peripheral nervous system. Their role is to accept the stimuli inside and outside the body and transmit them to the center nerve system to form sensations or reflexes.
CHEN Huidong, ZHANG Yunlong, ZHANG Zhijian, HUA Qingquan   +3 more
doaj   +1 more source

Integrating diverse datasets improves developmental enhancer prediction [PDF]

, 2013
Gene-regulatory enhancers have been identified by many lines of evidence, including evolutionary conservation, regulatory protein binding, chromatin modifications, and DNA sequence motifs. To integrate these different approaches, we developed EnhancerFinder, a novel method for predicting developmental enhancers and their tissue specificity ...
arxiv   +1 more source

The agrin gene codes for a family of basal lamina proteins that differ in function and distribution [PDF]

, 1992
We isolated two cDNAs that encode isoforms of agrin, the basal lamina protein that mediates the motor neuron-induced aggregation of acetylcholine receptors on muscle fibers at the neuromuscular junction.
Escher, G., Gensch, E. M., Horton, S. E., Kroger, S., McMahan, U. J., Ruegg, M. A., Tsim, K. W.   +6 more
core   +2 more sources

Differential gene and protein expression between rat tibial nerve and common peroneal nerve during Wallerian degeneration

Neural Regeneration Research, 2019
Wallerian degeneration and nerve regeneration after injury are complex processes involving many genes, proteins and cytokines. After different peripheral nerve injuries the regeneration rate can differ.
Yao-Fa Lin, Zheng Xie, Jun Zhou, Gang Yin, Hao-Dong Lin   +4 more
doaj   +1 more source

The injured sciatic nerve atlas (iSNAT), insights into the cellular and molecular basis of neural tissue degeneration and regeneration

eLife, 2022
Upon trauma, the adult murine peripheral nervous system (PNS) displays a remarkable degree of spontaneous anatomical and functional regeneration. To explore extrinsic mechanisms of neural repair, we carried out single-cell analysis of naïve mouse sciatic
Xiao-Feng Zhao, Lucas D Huffman, Hannah Hafner, Mitre Athaiya, Matthew C Finneran, Ashley L Kalinski, Rafi Kohen, Corey Flynn, Ryan Passino, Craig N Johnson, David Kohrman, Riki Kawaguchi, Lynda JS Yang, Jeffery L Twiss, Daniel H Geschwind, Gabriel Corfas, Roman J Giger   +16 more
doaj   +1 more source

Electrothermal equivalent three-dimensional Finite Element Model of a single neuron [PDF]

IEEE Transactions on Biomedical Engineering, 65 (2018) 1373-1381, 2020
Objective: We propose a novel approach for modelling the inter-dependence of electrical and mechanical phenomena in nervous cells, by using electro-thermal equivalences in finite element (FE) analysis so that existing thermo-mechanical tools can be applied. Methods: First, the equivalence between electrical and thermal properties of the nerve materials
arxiv   +1 more source

Therapeutic Potential of Extracellular Vesicles for the Treatment of Nerve Disorders

Frontiers in Neuroscience, 2019
The use of extracellular vesicles (EVs) as cell free therapy is a promising approach to stimulate tissue regeneration including that of the nervous system.
L. R. Galieva, V. James, Y. Mukhamedshina, A. Rizvanov   +3 more
semanticscholar   +1 more source