Results 81 to 90 of about 3,905,054 (299)
Nerve tissue engineering using blends of Polyhydroxyalkanoates [PDF]
, 2017 PHAs are a family of linear polyesters consisting of 3, 4, 5 and 6-hydroxyacids, synthesized by a variety of bacterial species. They can be produced from renewable carbon sources, they are biodegradable, biocompatible and exhibit thermoplastic and ...
Lizarraga Valderrama, L.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Peripheral nerve tissue engineering
, 2014 The chapter summarises the pathophysiological response to peripheral nerve injury and subsequent regeneration reactions, with a particular focus on nerve gap injuries.
M.K. Kolar +3 more
core +1 more source
Not more than three tissue kallikreins identified from organs of the guinea pig [PDF]
, 1999 The large and varied multigene families of tissue kallikreins of rat and mouse are considered to selectively release as many bioactive peptides. In order to determine whether a similar family of enzymes is expressed in the organs of the guinea pig ...
Fiedler, F. +5 more
core +1 more source
Experimental GerontologyObjective: Ferroptosis represents a form of regulated cellular death dependent upon iron and lipid peroxidation derivatives, holding considerable implications for cerebral and neurologic pathologies.
Ying-jun Zhong +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Putative intermediates in the nerve cell differentiation pathway in hydra have properties of multipotent stem cells [PDF]
, 1990 We have investigated the properties of nerve cell precursors in hydra by analyzing the differentiation and proliferation capacity of interstitial cells in the peduncle of Hydra oligactis, which is a region of active nerve cell differentiation.
Charles +4 more
core +1 more source
Structural and dynamical properties of central nervous system proteins with pharmaceutical and biotechnological potential. [PDF]
, 2010 Neurodegenerative diseases are widespread pathologies of large social impact that include: prion, Alzheimer and Parkinson disease, Huntington chorea and amyotrophic lateral sclerosis.
Stanzione, Francesca
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source