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SYMPATHETIC NERVOUS SYSTEM [PDF]
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W. Langdon Brown
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“The Nervous System and the Mind” [PDF]
WILL you allow me to account for one or two of the discrepancies in my book which your very able reviewer points out in the current issue of NATURE?
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Background Glioblastoma (GBM) is a brain tumor with the highest level of malignancy and the worst prognosis in the central nervous system. Mitochondrial metabolism plays a vital role in the occurrence and development of cancer, which provides critical ...
Tongxuan Guo+10 more
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Temozolomide (TMZ) is a conventional chemotherapeutic drug for glioma, however, its clinical application and efficacy is severely restricted by its drug resistance properties.
Haoyue Xu+9 more
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YAP promotes autophagy and progression of gliomas via upregulating HMGB1
Background Due to the hypoxia and nutrient deficiency microenvironment, glioblastoma (GBM) exhibits high autophagy activity and autophagy plays an important role in the progression of GBM.
Min Zhao+8 more
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Dual blockade of EGFR and PI3K signaling pathways offers a therapeutic strategy for glioblastoma
Background Glioblastoma multiforme (GBM) is a devastating disease that lacks effective drugs for targeted therapy. Previously, we found that the third-generation epidermal growth factor receptor (EGFR) inhibitor AZD-9291 persistently blocked the ...
Tongxuan Guo+8 more
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GRP78 blockade overcomes intrinsic resistance to UBA1 inhibitor TAK-243 in glioblastoma
Glioblastoma multiforme (GBM) is the most aggressive malignant primary brain tumor of the central nervous system. Despite continuous progression in treatment options for GBM like surgery, radiotherapy, and chemotherapy, this disease still has a high rate
Xu Zhang+10 more
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Background After diagnosis, glioblastoma (GBM) patients undertake tremendous psychological problems such as anxiety and depression, which may contribute to GBM progression.
Yan Wang+10 more
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Background The postoperative recurrence of malignant gliomas has presented a clinical conundrum currently. Worse, there is no standard treatment for these recurrent tumours.
Yufu Zhu+10 more
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Birth weight and heart rate autonomic recovery following exercise in healthy term-born adults
The impact of birth weight (BW) on adult health has been studied, related to the autonomic nervous system, and implicated in cardiovascular risk. We investigated cardiorespiratory and heart rate (HR) autonomic recovery after moderate effort in healthy ...
Giovanna de Paula Vidigal+3 more
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