Results 21 to 30 of about 24,153,656 (297)

In vivo performance of Al2O3-Ti bone implants in the rat femur

Journal of Orthopaedic Surgery and Research, 2021
Background Alumina-titanium (Al2O3-Ti) biocomposites have been recently developed with improved mechanical properties for use in heavily loaded orthopedic sites. Their biological performance, however, has not been investigated yet. Methods The aim of the
Marjan Bahraminasab, Samaneh Arab, Manouchehr Safari, Athar Talebi, Fatemeh Kavakebian, Nesa Doostmohammadi   +5 more
doaj   +1 more source

Lipid droplets in the nervous system

Journal of Cell Biology, 2021
Ralhan et al. review the emerging role of lipid droplets in the nervous system in development, aging, and disease.
Isha Ralhan, Chi-Lun Chang, J. Lippincott-Schwartz, Maria S. Ioannou   +3 more
semanticscholar   +1 more source

CRM1/XPO1 is associated with clinical outcome in glioma and represents a therapeutic target by perturbing multiple core pathways

Journal of Hematology & Oncology, 2016
Background Malignant gliomas are associated with a high mortality rate, and effective treatment options are limited. Thus, the development of novel targeted treatments to battle this deadly disease is imperative.
Xuejiao Liu, Yulong Chong, Yiming Tu, Ning Liu, Chenglong Yue, Zhenglei Qi, Huize Liu, Yao Yao, Hongmei Liu, Shangfeng Gao, Mingshan Niu, Rutong Yu   +11 more
doaj   +1 more source

Plumbagin inhibits growth of gliomas in vivo via suppression of FOXM1 expression

Journal of Pharmacological Sciences, 2015
Plumbagin is a natural compound that is isolated from the root of the medicinal plant Plumbago zeylanica L. Based on a previous in vitro study performed by our group, which demonstrated the effectiveness of plumbagin against glioma cells, we further ...
Mingshan Niu, Wei Cai, Huize Liu, Yulong Chong, Wenqiang Hu, Shangfeng Gao, Qiong Shi, Xiuping Zhou, Xuejiao Liu, Rutong Yu   +9 more
doaj   +1 more source

COVID‐19: A Global Threat to the Nervous System

Annals of Neurology, 2020
In less than 6 months, the severe acute respiratory syndrome‐coronavirus type 2 (SARS‐CoV‐2) has spread worldwide infecting nearly 6 million people and killing over 350,000.
I. Koralnik, K. Tyler
semanticscholar   +1 more source

The functional diversity of Aurora kinases: a comprehensive review

Cell Division, 2018
Aurora kinases are serine/threonine kinases essential for the onset and progression of mitosis. Aurora members share a similar protein structure and kinase activity, but exhibit distinct cellular and subcellular localization.
Estelle Willems, Matthias Dedobbeleer, Marina Digregorio, Arnaud Lombard, Paul Noel Lumapat, Bernard Rogister   +5 more
doaj   +1 more source

The third-generation EGFR inhibitor AZD9291 overcomes primary resistance by continuously blocking ERK signaling in glioblastoma

Journal of Experimental & Clinical Cancer Research, 2019
Background Glioblastoma (GBM) is a fatal brain tumor, lacking effective treatment. Epidermal growth factor receptor (EGFR) is recognized as an attractive target for GBM treatment. However, GBMs have very poor responses to the first- and second-generation
Xuejiao Liu, Xiangyu Chen, Lin Shi, Qianqian Shan, Qiyu Cao, Chenglong Yue, Huan Li, Shengsheng Li, Jie Wang, Shangfeng Gao, Mingshan Niu, Rutong Yu   +11 more
doaj   +1 more source

Anti-MOG associated myelitis

Неврология, нейропсихиатрия, психосоматика, 2020
There is now increasing evidence that demyelinating disease with anti-myelin oligodendrocyte glycoprotein (anti-MOG) antibodies is an independent nosological unit.
A. I. Isaykin, O. N. Voskresenskaya, T. I. Kuzminova, E. V. Ermilova, O. V. Stezhko   +4 more
doaj   +1 more source

Infections of the Central Nervous System

Annals of Internal Medicine, 1992
This chapter describes and illustrates the different lesions observed in central nervous system (CNS) infections. A wide variety of pathogenic infectious organisms may affect the CNS.
Mateusz Dobosz, Klaudia Arciszewska, Aleksandra Bogoń, Jakub Buczkowski, Jakub Maciej Pieniążek, Aleksandra Padkowska, Michał Paprocki, Anna Mataczyńska, Aleksandra Laskowska   +8 more
semanticscholar   +1 more source

Delayed diagnosis of the neuromyelitis optica spectrum disorder

Неврология, нейропсихиатрия, психосоматика, 2023
Neuromyelitis optica spectrum disorders (NMOSD) are a group of autoimmune inflammatory demyelinating diseases of the central nervous system. In 2015, International Expert Panel established diagnostic criteria for NMOSD.
S. A. Dzhukkaeva, E. V. Ermilova, Sh. R. Nabiev, O. N. Voskresenskaya   +3 more
doaj   +1 more source