The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Case report and literature review: Novel compound heterozygous FIG4 variants causing both of peripheral and central nervous system defects. [PDF]
Yu Y +6 more
europepmc +1 more source
Interactions between Type III receptor tyrosine phosphatases and growth factor receptor tyrosine kinases regulate tracheal tube formation in Drosophila [PDF]
The respiratory (tracheal) system of the Drosophila melanogaster larva is an intricate branched network of air-filled tubes. Its developmental logic is similar in some ways to that of the vertebrate vascular system.
Jeon, Mili, Scott, Matthew P., Zinn, Kai
core +3 more sources
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo +6 more
wiley +1 more source
Mechanisms of prickle1a function in zebrafish epilepsy and retinal neurogenesis
SUMMARY Epilepsy is a complex neurological disorder characterized by unprovoked seizures. The etiology is heterogeneous with both genetic and environmental causes.
Xue Mei +3 more
doaj +1 more source
The Assessment of the Usefulness of Prenatal Magnetic Resonance Imaging in the Diagnosis of Central Nervous System Defects. [PDF]
Kołak M +5 more
europepmc +1 more source
Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami +4 more
wiley +1 more source
Prenatal Diagnosis and Management of Congenital Abnormalities of Central Nervous System
Among the congenital anomalies, central nervous system malformations are the most commonly seen ones whose antenatal sonographic diagnosis is very important.
Ülkü Bayar +4 more
doaj
Investigating the Interactions Between Protocadherin-19 and Ryk and its Effect on Neurogenesis [PDF]
Protocadherins are a large, diverse family of neural cell adhesion proteins, but their functions are not understood. Mutations or in several protocadherins have been associated with neurological disorders.
Liebau, Brandon
core
The PSI-U1 snRNP interaction regulates male mating behavior in Drosophila
Alternative pre-mRNA splicing (AS) is a critical regulatory mechanism that operates extensively in the nervous system to produce diverse protein isoforms.
Hilgers, V. +5 more
core +1 more source

