Results 101 to 110 of about 1,154,997 (309)

Quality of Life and the Degree of Disease Acceptance In Patients with Spinocerebellar Ataxia

open access: yesPielęgniarstwo Neurologiczne i Neurochirurgiczne, 2018
Introduction. Spinocerebellar ataxias (SCA) belong to a group of rare genetic diseases. They are characterized by the multiplicity of symptoms, of which the most characteristic is limb ataxia and dysarthria.
Magdalena Kazimierska-Zając   +2 more
doaj   +1 more source

Diseases of the Nervous System [PDF]

open access: yesAnnual Review of Medicine, 1957
R A, FISHMAN, H H, MERRITT
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Neurologopedic Correlates of Cognitive Ageing and Dementia

open access: yesPielęgniarstwo Neurologiczne i Neurochirurgiczne, 2016
Introduction. Aging is the subject of interest of many fields of science. Equal place of neurologopedic studies do not raise doubts today — patients followed for deterioration not only of elementary cognitive functions as memory, perception and attention,
Joanna Rosińczuk   +2 more
doaj   +1 more source

Role of Nuclear Receptors in Central Nervous System Development and Associated Diseases [PDF]

open access: yes, 2016
The nuclear hormone receptor (NHR) superfamily is composed of a wide range of receptors involved in a myriad of important biological processes, including development, growth, metabolism, and maintenance.
Oscar Andrés Moreno-Ramos   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Biological markers of Alzheimer's disease in cerebrospinal fluid: clinical and laboratory comparisons

open access: yesНеврология, нейропсихиатрия, психосоматика
Diagnostic hypothesis of Alzheimer's disease (AD) is based on the typical clinical picture of the disease and the exclusion of other diseases manifesting by cognitive and behavioural disorders by MRI scans of the brain and laboratory tests.
K. V. Shevtsova   +12 more
doaj   +1 more source

Early Therapeutic Intervention in a Child with Beckwith–Wiedemann Syndrome in Inpatient and Outpatient Conditions — Case Report

open access: yesPielęgniarstwo Neurologiczne i Neurochirurgiczne, 2019
Introduction. The Beckwith–Wiedemann syndrome (BWS) is a rare disorder characterized by a wide spectrum of symptoms i.a. umbilical hernia or omphalocele, macroglossia and above-average pre/postnatal growth (macrosomia). Aim. To present a case report of a
Teresa Kaczan   +4 more
doaj   +1 more source

Microglia lactylation in relation to central nervous system diseases [PDF]

open access: yes
The development of neurodegenerative diseases is closely related to the disruption of central nervous system homeostasis. Microglia, as innate immune cells, play important roles in the maintenance of central nervous system homeostasis, injury response ...
Mo, Nan   +15 more
core   +1 more source

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