Results 11 to 20 of about 2,663,952 (341)
NLRP3 inflammasome in neuroinflammation and central nervous system diseases. [PDF]
Cell Mol ImmunolNeuroinflammation plays an important role in the pathogenesis of various central nervous system (CNS) diseases. The NLRP3 inflammasome is an important intracellular multiprotein complex composed of the innate immune receptor NLRP3, the adaptor protein ...
Xu W, Huang Y, Zhou R.
europepmc +2 more sources
The blood-brain barriers: novel nanocarriers for central nervous system diseases. [PDF]
J NanobiotechnologyThe central nervous system (CNS) diseases are major contributors to death and disability worldwide. However, the blood–brain barrier (BBB) often prevents drugs intended for CNS diseases from effectively crossing into the brain parenchyma to deliver their
Liu J, Wang T, Dong J, Lu Y.
europepmc +2 more sources
Copper homeostasis and cuproptosis in central nervous system diseases. [PDF]
Cell Death DisCopper (Cu), an indispensable micronutrient for the sustenance of living organisms, contributes significantly to a vast array of fundamental metabolic processes.
Zhu Z +5 more
europepmc +2 more sources
Astrocytes in human central nervous system diseases: a frontier for new therapies
Signal Transduction and Targeted Therapy, 2023 Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis and defence of the central nervous system (CNS). Astroglia contribute to the pathophysiology of all neurological and neuropsychiatric disorders in ways that can ...
Alexei Verkhratsky +7 more
semanticscholar +1 more source
ACSL4-Mediated Ferroptosis and Its Potential Role in Central Nervous System Diseases and Injuries
International Journal of Molecular Sciences, 2023 As an iron-dependent regulated form of cell death, ferroptosis is characterized by iron-dependent lipid peroxidation and has been implicated in the occurrence and development of various diseases, including nervous system diseases and injuries ...
Bowen Jia +3 more
semanticscholar +1 more source
Aging and Disease, 2023 The metabolism of L-tryptophan (TRP) regulates homeostasis, immunity, and neuronal function. Altered TRP metabolism has been implicated in the pathophysiology of various diseases of the central nervous system. TRP is metabolized through two main pathways,
Yinrou Huang +12 more
semanticscholar +1 more source
Role of exosomes in the pathogenesis, diagnosis, and treatment of central nervous system diseases
Journal of Translational Medicine, 2022 Central nervous system (CNS) diseases, such as multiple sclerosis, Alzheimer's disease (AD), and Parkinson’s disease (PD), affect millions of people around the world.
Yishu Fan, Zhuohui Chen, Mengqi Zhang
semanticscholar +1 more source
The role of gamma oscillations in central nervous system diseases: Mechanism and treatment
Frontiers in Cellular Neuroscience, 2022 Gamma oscillation is the synchronization with a frequency of 30–90 Hz of neural oscillations, which are rhythmic electric processes of neuron groups in the brain.
Ao Guan +8 more
semanticscholar +1 more source
CNS Neuroscience & Therapeutics, 2023 Mitochondria is one of the important organelles involved in cell energy metabolism and regulation and also play a key regulatory role in abnormal cell processes such as cell stress, cell damage, and cell canceration.
Ziang Geng +6 more
semanticscholar +1 more source
The Pharmacological Action of Kaempferol in Central Nervous System Diseases: A Review
Frontiers in Pharmacology, 2021 Kaempferol (KPF) is a flavonoid antioxidant found in fruits and vegetables. Many studies have described the beneficial effects of dietary KPF in reducing the risk of chronic diseases, especially cancer.
Jéssica Silva dos Santos +3 more
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