Results 31 to 40 of about 20,086,433 (308)

Stepwise-targeting and hypoxia-responsive liposome AMVY@NPs carrying siYAP and verteporfin for glioblastoma therapy

open access: yesJournal of Nanobiotechnology
Background The Hippo pathway is a conserved tumour suppressor signalling pathway, and its dysregulation is often associated with abnormal cell growth and tumorigenesis.
Ji Qi   +11 more
doaj   +1 more source

UBA1 inhibition contributes radiosensitization of glioblastoma cells via blocking DNA damage repair

open access: yesFrontiers in Pharmacology, 2023
Glioblastoma multiforme (GBM) is a brain tumor with high mortality and recurrence rate. Radiotherapy and chemotherapy after surgery are the main treatment options available for GBM. However, patients with glioblastoma have a grave prognosis.
Changyong Wu   +16 more
doaj   +1 more source

Trauma and Diseases of the Nervous System [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1904
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openaire   +1 more source

Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin   +11 more
wiley   +1 more source

SWAP-70 promotes glioblastoma cellular migration and invasion by regulating the expression of CD44s

open access: yesCancer Cell International, 2019
Background Switch-associated protein 70 (SWAP-70) is a guanine nucleotide exchange factor that is involved in cytoskeletal rearrangement and regulation of migration and invasion of malignant tumors.
Lin Shi   +12 more
doaj   +1 more source

Overview of neglected tropical diseases and conditions of the nervous system: past, present and perspectives.

open access: yes, 2014
Neglected tropical diseases consist of a group of infectious diseases with the unifying features of being poverty-related, prevalent in tropical and subtropical regions, and absent from the public health agenda in wealthy countries.
BENTIVOGLIO FALES, Marina   +7 more
core   +1 more source

Antibody-mediated central nervous system diseases. [PDF]

open access: yes, 2021
Antibody-mediated central nervous system diseases are a relatively new area of clinical neuroscience with growing impact. Their recognition has challenged the dogma of the blood-brain barrier preventing antibody access into the central nervous system ...

core   +2 more sources

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan   +3 more
wiley   +1 more source

Nervous System Lyme Disease

open access: yesInfectious Disease Clinics of North America, 1998
Lyme disease, the multi-system infection caused by the tick-borne spirochaete Borrelia burgdorferi, can involve the nervous system, most commonly causing, alone or in combination, lymphocytic meningitis or abnormalities of cranial or peripheral nerves, the latter most typically presenting as a painful radicular syndrome.
openaire   +9 more sources

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