Results 31 to 40 of about 1,154,997 (309)

Comprehensive profiling of stem-like features in pediatric glioma cell cultures and their relation to the subventricular zone

open access: yesActa Neuropathologica Communications, 2023
Pediatric high-grade gliomas (pHGG) are brain tumors occurring in children and adolescents associated with a dismal prognosis despite existing treatments. Therapeutic failure in both adult and pHGG has been partially imputed to glioma stem cells (GSC), a
Marc-Antoine Da-Veiga   +5 more
doaj   +1 more source

NMDA receptors in nervous system diseases [PDF]

open access: yes, 2013
NMDA receptor (NMDAR) dysfunction has emerged as a common theme in several major nervous system disorders, including ischemic brain injury, chronic neurodegenerative diseases, pain, depression and schizophrenia.
Sheng, Morgan, Zhou, Qiang
core   +1 more source

RETRACTED ARTICLE: GRP78 determines glioblastoma sensitivity to UBA1 inhibition-induced UPR signaling and cell death

open access: yesCell Death and Disease, 2021
Glioblastoma multiforme (GBM) is an extremely aggressive brain tumor for which new therapeutic approaches are urgently required. Unfolded protein response (UPR) plays an important role in the progression of GBM and is a promising target for developing ...
Guanzheng Liu   +13 more
doaj   +1 more source

Identifying Common Genes, Cell Types and Brain Regions Between Diseases of the Nervous System [PDF]

open access: yes, 2019
Background: Diseases of the nervous system are widely considered to be caused by genetic mutations, and they have been shown to share pathogenic genes. Discovering the shared mechanisms of these diseases is useful for designing common treatments. Method:
Wang, Z   +12 more
core   +1 more source

Cognitive impairments in patients with prior ischemic stroke

open access: yesНеврология, нейропсихиатрия, психосоматика, 2014
The authors give the data available in the literature on and the results of their studies of the epidemiology, risk factors, pathogenesis, diagnosis, and treatment of poststroke cognitive impairment (PSCI).
V. A. Parfenov   +4 more
doaj   +1 more source

Hereditary neuropathy with liability to pressure palsies: a case report

open access: yesНеврология, нейропсихиатрия, психосоматика, 2021
Hereditary neuropathy with liability to pressure palsies (HNPP) is a rare hereditary disorder characterized by recurrent episodes of nerve compression. The first attack usually occurs in the second or third decade of life.
A. K. Polynnikova   +3 more
doaj   +1 more source

Charles West: a 19th century perspective on acquired childhood aphasia [PDF]

open access: yes, 2005
Dr Charles West was the founder (1852) of the first paediatric hospital in the English-speaking world. In a career spanning four decades, he devoted a great part of his energies to describing the nervous diseases of infants and children.
Lorch, Marjorie, Hellal, Paula
core   +1 more source

Central pontine myelinolysis in the presence of SARS-CoV-2 infection (clinical observations)

open access: yesНеврология, нейропсихиатрия, психосоматика, 2021
Osmotic demyelinating syndrome (ODS) is a severe complication that occurs due to rapid correction of hyponatremia. Central  pontine myelinolysis (CPM), in which a focus of demyelination  occurs in the pontine region, and extrapontine myelinolysis (EPM), 
O. N. Voskresenskaya   +5 more
doaj   +1 more source

Treatment update for autoimmune/immune-mediated central nervous system diseases [PDF]

open access: yes
Autoimmune/immune-mediated central nervous system (CNS) diseases are chronic, inflammatory, autoimmune diseases, such as multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and autoimmune encephalitis (AE).
Wan Fu   +5 more
core   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan   +1 more
wiley   +1 more source

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