Results 11 to 20 of about 20,086,433 (308)

Delayed diagnosis of the neuromyelitis optica spectrum disorder

Неврология, нейропсихиатрия, психосоматика, 2023
Neuromyelitis optica spectrum disorders (NMOSD) are a group of autoimmune inflammatory demyelinating diseases of the central nervous system. In 2015, International Expert Panel established diagnostic criteria for NMOSD.
S. A. Dzhukkaeva, E. V. Ermilova, Sh. R. Nabiev, O. N. Voskresenskaya   +3 more
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Diseases of the Peripheral Nervous System [PDF]

, 2022
With the rapid development of information technology in the world today, many new symptoms of many diseases are being identified. Especially in this regard, much higher results are being achieved in diseases of the nervous system.
Khodjaeva Gulnora Abdubannonovna, assistant
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Anti-MOG associated myelitis

Неврология, нейропсихиатрия, психосоматика, 2020
There is now increasing evidence that demyelinating disease with anti-myelin oligodendrocyte glycoprotein (anti-MOG) antibodies is an independent nosological unit.
A. I. Isaykin, O. N. Voskresenskaya, T. I. Kuzminova, E. V. Ermilova, O. V. Stezhko   +4 more
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CRM1/XPO1 is associated with clinical outcome in glioma and represents a therapeutic target by perturbing multiple core pathways

Journal of Hematology & Oncology, 2016
Background Malignant gliomas are associated with a high mortality rate, and effective treatment options are limited. Thus, the development of novel targeted treatments to battle this deadly disease is imperative.
Xuejiao Liu, Yulong Chong, Yiming Tu, Ning Liu, Chenglong Yue, Zhenglei Qi, Huize Liu, Yao Yao, Hongmei Liu, Shangfeng Gao, Mingshan Niu, Rutong Yu   +11 more
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Plumbagin inhibits growth of gliomas in vivo via suppression of FOXM1 expression

Journal of Pharmacological Sciences, 2015
Plumbagin is a natural compound that is isolated from the root of the medicinal plant Plumbago zeylanica L. Based on a previous in vitro study performed by our group, which demonstrated the effectiveness of plumbagin against glioma cells, we further ...
Mingshan Niu, Wei Cai, Huize Liu, Yulong Chong, Wenqiang Hu, Shangfeng Gao, Qiong Shi, Xiuping Zhou, Xuejiao Liu, Rutong Yu   +9 more
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Reversible inhibitor of CRM1 sensitizes glioblastoma cells to radiation by blocking the NF-κB signaling pathway

Cancer Cell International, 2020
Background Activation of nuclear factor-kappa B (NF-κΒ) through DNA damage is one of the causes of tumor cell resistance to radiotherapy. Chromosome region 1 (CRM1) regulates tumor cell proliferation, drug resistance, and radiation resistance by ...
Xuejiao Liu, Yiming Tu, Yifeng Wang, Di Zhou, Yulong Chong, Lin Shi, Guanzheng Liu, Xu Zhang, Sijin Wu, Huan Li, Shangfeng Gao, Mingshan Niu, Rutong Yu   +12 more
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Hydrotherapy in nervous system diseases [PDF]

, 2019
SUMMARY Hydrotherapy is one method used in the rehabilitation treatment of various diseases, including diseases of the nervous system with a positive result. It is used in many exercise programs.
Joanna Iłżecka, Iłżecka, Joanna
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The effect of biologically active compounds in the mucus of slugs Limax maximus and Arion rufus on human skin cells

Scientific Reports, 2021
Molluscs are one of the sources of biologically active substances, which are now intensively studied, especially for their anti-cancer properties. Malignant melanoma originates from melanocytes, develops very quickly and is associated with poor prognosis.
Leśków Anna, Tarnowska Małgorzata, Szczuka Izabela, Diakowska Dorota   +3 more
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The functional diversity of Aurora kinases: a comprehensive review

Cell Division, 2018
Aurora kinases are serine/threonine kinases essential for the onset and progression of mitosis. Aurora members share a similar protein structure and kinase activity, but exhibit distinct cellular and subcellular localization.
Estelle Willems, Matthias Dedobbeleer, Marina Digregorio, Arnaud Lombard, Paul Noel Lumapat, Bernard Rogister   +5 more
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The third-generation EGFR inhibitor AZD9291 overcomes primary resistance by continuously blocking ERK signaling in glioblastoma

Journal of Experimental & Clinical Cancer Research, 2019
Background Glioblastoma (GBM) is a fatal brain tumor, lacking effective treatment. Epidermal growth factor receptor (EGFR) is recognized as an attractive target for GBM treatment. However, GBMs have very poor responses to the first- and second-generation
Xuejiao Liu, Xiangyu Chen, Lin Shi, Qianqian Shan, Qiyu Cao, Chenglong Yue, Huan Li, Shengsheng Li, Jie Wang, Shangfeng Gao, Mingshan Niu, Rutong Yu   +11 more
doaj   +1 more source