Results 21 to 30 of about 1,154,997 (309)
Plumbagin inhibits growth of gliomas in vivo via suppression of FOXM1 expression
Journal of Pharmacological Sciences, 2015 Plumbagin is a natural compound that is isolated from the root of the medicinal plant Plumbago zeylanica L. Based on a previous in vitro study performed by our group, which demonstrated the effectiveness of plumbagin against glioma cells, we further ...
Mingshan Niu +9 more
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Cancer Cell International, 2020 Background Activation of nuclear factor-kappa B (NF-κΒ) through DNA damage is one of the causes of tumor cell resistance to radiotherapy. Chromosome region 1 (CRM1) regulates tumor cell proliferation, drug resistance, and radiation resistance by ...
Xuejiao Liu +12 more
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Scientific Reports, 2021 Molluscs are one of the sources of biologically active substances, which are now intensively studied, especially for their anti-cancer properties. Malignant melanoma originates from melanocytes, develops very quickly and is associated with poor prognosis.
Leśków Anna +3 more
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The functional diversity of Aurora kinases: a comprehensive review
Cell Division, 2018 Aurora kinases are serine/threonine kinases essential for the onset and progression of mitosis. Aurora members share a similar protein structure and kinase activity, but exhibit distinct cellular and subcellular localization.
Estelle Willems +5 more
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EARLY DIAGNOSIS AND PREVENTION OF NERVOUS SYSTEM DISEASES [PDF]
, 2023 Early diagnosis and prevention of nervous system diseases have gained paramount significance in contemporary medical research and healthcare. The nervous system plays a pivotal role in coordinating and regulating bodily functions, and any dysfunction can
Muxamedova Nigora, Arifbaeva Dilnoza, Mukhiddinova Iroda, Akhmatov Diorbek
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Journal of Experimental & Clinical Cancer Research, 2019 Background Glioblastoma (GBM) is a fatal brain tumor, lacking effective treatment. Epidermal growth factor receptor (EGFR) is recognized as an attractive target for GBM treatment. However, GBMs have very poor responses to the first- and second-generation
Xuejiao Liu +11 more
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Translational Psychiatry, 2023 Cognitive impairment is a core feature of schizophrenia and is poorly addressed by currently available medication. This is partly because the underlying circuits are insufficiently understood, and available animal models for brain dysfunction do not ...
Oana-Daniela Dormann +2 more
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The Sympathetic Nervous System in Disease [PDF]
The Journal of Nervous and Mental Disease, 1922 n ...
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Crossing the blood-brain barrier: a review on drug delivery strategies for treatment of the central nervous system diseases [PDF]
, 2019 Many drugs have been designed to treat diseases of the central nervous system (CNS), especially neurodegenerative diseases. However, the presence of tight junctions at the blood-brain barrier has often compromised the efficiency of drug delivery to ...
Ling, King Hwa +6 more
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