Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs
Advanced Healthcare Materials, EarlyView.This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani +4 more
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The Role and Mechanism of Metformin in the Treatment of Nervous System Diseases. [PDF]
BiomoleculesLi H, Liu R, Liu J, Qu Y.
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The Outlines of Insanity. A Course of Lectures Delivered at the Albany Medical College during January and February, 1891.By Henry Hun, M. D., Professor of Diseases of the Chest and Nervous System. Reprinted from theAlbany Medical Annals,July-October, 1891 [PDF]
, 1892 J. M. M.
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Advanced Healthcare Materials, EarlyView.A new oxaliplatin‐based Pt(IV) prodrug bearing a Mn(II) superoxide dismutase mimic is synthesized and studied, in vitro and in vivo, in the context of colorectal cancer. Encapsulation of this prodrug in an easy‐to‐implement PEGylated micelle formulation demonstrated the highest in vivo anticancer activity among all the tested conditions, supporting the
Alvaro Lopez‐Sanchez +14 more
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Targeting Neuroinflammation in Central Nervous System Diseases by Oral Delivery of Lipid Nanoparticles. [PDF]
PharmaceuticsZou Y +5 more
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Advanced Healthcare Materials, EarlyView.This study introduces a wireless and miniaturized concentric‐electrode tDCS (CE‐tDCS) system tailored for freely moving mice. The device enables focal and multi‐site cortical stimulation via a lightweight, Bluetooth‐controlled platform. By integrating local neuromodulation with real‐time behavioral analysis, the system provides a robust tool for ...
Minseok Kim +5 more
wiley +1 more source
Intranasal Drug Delivery Technology in the Treatment of Central Nervous System Diseases: Challenges, Advances, and Future Research Directions. [PDF]
PharmaceuticsWu X +8 more
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A review on recent advances on nobiletin in central and peripheral nervous system diseases. [PDF]
Eur J Med Res, 2023 Pang Y, Xiong J, Wu Y, Ding W.
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ILLUSTRATIONS OF IMPAIRMENT OF THE POWER OF INTEL LIGENT LANGUAGE, IN CONNEXION WITH DISEASE OF THE NERVOUS SYSTEM. [PDF]
, 1870 J OGLE
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